ASSESSMENT OF PRIMARY HEMOSTASIS 1.BLEEDING TIME Bleeding time is used to measure the duration of bleeding after a measured skin incision. Bleeding time may be measured by one of three methods: template‚ Ivy‚ or Duke. The template method is the most commonly used and the most accurate because the incision size is standardized. Bleeding time depends on the elasticity of the blood vessel wall and on the number and functional capacity of platelets. Although this test is usually performed on
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compound. Part 2: The aim of separation technique by Thin Layer Chromatography is to separate the mixture of individual compounds from the spinach leaf sample used. Material and apparatus: Part 1 : Analysis of Analgesic Drugs Material: Aspirin Acetaminophen Caffeine Unknown A Unknown B TLC plates Ethyl acetate Hexane Acetic acid Iodine Apparatus: UV Lamp Capillary tube 250mL beaker Filter paper
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Measles According to the CDC (Centers for Disease Control)‚ measles is an airborne disease that is spread through respiration (contact with fluids from an infected person’s nose and mouth‚ either directly or through aerosol transmission (coughing or sneezing)‚ and is highly contagious. Measles is caused by the measles virus‚ a single-stranded‚ negative-sense‚ enveloped RNA virus of the genus Morbillivirus within the family Paramyxoviridae. The classic signs and symptoms of of measles include four-days
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appear to cause ulcer disease. * The incidence of duodenal ulcer disease has been declining dramatically for the last 30 years‚ but the incidence of gastric ulcers appears to be increasing as a result of the widespread use of NSAIDs and low-dose aspirin. Reason for the Development/ Occcurence of the Disease Three major causes of peptic ulcer disease are now reorganized: NSAIDs‚ chronic H pylori infection‚ and acid hypersecretory staes such as Zollinger-Ellison syndrome. Evidence of H pylori infection
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to visit and finds him struggling to breathe‚ and was grasping at his chest. He dials 911 and then having remembered a commercial for Bayer aspirin that mentioned taking an aspirin during a heart attack can help‚ she goes into her purse and gets an aspirin to give to her friend while they are awaiting the arrival of rescue crews. After giving him the aspirin‚ his symptoms worsen and by the time paramedics arrive‚ the man was dead. After autopsy‚ information was revealed that the man died from an
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It is suggested that direct oral anticoagulant users monitor therapy if using combined with p-gp and/or CYP3A4 inducers/inhibitors.4 Also use of aspirin with direct oral anticoagulants is prohibited unless benefits clearly outweigh risk.4 E.P. is currently on aspirin‚ if he is placed on a direct oral anticoagulant‚ we suggest discontinuation of the aspirin. According to a guidance article published in Journal of Thrombosis and Thrombolysis‚ when switching from
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. Update Article NSAIDs and Kidney P Ejaz‚ K Bhojani‚ VR Joshi* Abstract NSAIDs are commonly used drugs. Even with the advent of selective COX-2 inhibitors‚ nephrotoxicity still remains a concern. The adverse effects of NSAIDs are mediated via inhibition of prostaglandin synthesis from arachidonic acid by non-specific blocking of the enzyme cyclooxygenase leading to vasoconstriction and reversible mild renal impairment in volume contracted states. When unopposed‚ this may lead to acute tubular
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TLC is used because it is “sensitive‚ fast‚ simple and inexpensive analytical technique”2 (Mohrig 151). The unknown solid (unknown #3 in this case) used in the experiment was obtained and added to a 2.5ml of Ethanol/dichloromethane in a test tube. This was the solvent used in the experiment because Dichloromethane volatility and ability to dissolve a wide range of organic compounds makes it a useful solvent for many chemical processes. The solid was already in powder form therefore we did not have
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Thrombosis Research Institute used human umbilical vein endothelial cells and treated it with Panax Notoginseng Saponin‚ Aspirin‚ or no drug before exposing it to low-density lipoprotein for 16 hours. The results were that Panax Notoginseng Saponin had a similar effect on platelet activation to Aspirin‚ but a bigger impact than Aspirin. What they found was that Panax Notoginseng Saponin could control as well as regulate COX-2 expression which is cyclooxygenase tissue that is
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Determining Acids and Bases With Homemade pH Indicator Strips Made With Red Cabbage Juice Period 0 IB Chemisty Annie Truong Ms. Tran Purpose: The purpose of this lab is to make homemade pH indicator strips using red cabbage juice as the main ingredient and estimate the pH of different substances with these strips. Background Information: Acids and bases have properties of modifying the color of certain substances. The juice of the red cabbage is a blue-violet color and when it comes in
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