If I want to target the peptide to different compartments‚ I would use specific signal sequences or uptake-targeting sequences encoded into my peptide. Signal sequences contain information that will target the peptide to a particular organelle. The information is usually encoded within amino acid sequences of the protein itself‚ usually within the 20-50 amino acids. Also‚ each organelle has specific set of receptors that bind only to the specific signal sequences‚ thus making sure of target specificity
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Aspirin or acetylsalicylate acid is a compound that is widely used in medicine. The use of aspirin in medicine began long before the active reagent was removed from its natural source. The first documented use of aspirin was found in the writings of Hippocrates‚ the so called father of medicine. Hippocrates prescribed that willow bark could be used to remedy a wide range of conditions such as pain‚ fever and inflammation. Scientists began to seek to extract the active compound from willow tree bark
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Materials & Methods Synthesis Procedure of PDA@MT Polydopamine is synthesized through covalent polymerization similar to melanin biosynthesis‚ with DA oxidized to dopamine quinone‚ then further oxidized to DHI‚ which undergoes deprotonation and cross-linking via Michael addition to form PDA. A solution was prepared to synthesize PDA by mixing 90 mL of water‚ 40 mL of ethanol‚ and 3 mL of ammonia solution in a 300 mL beaker. After stirring for 30 minutes at 37°C‚ a solution of 500 mg of DA dissolved
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October 17 & October 24‚ 2012 How is Aspirin Made? This lab is about synthesizing aspirin using a hotplate to heat the reaction. It involved vacuum filtration‚ recrystallization‚ and comparing the properties of aspirin with salicylic aspirin. The first thing we did in this lab was make a hot-water bath by putting a beaker with water on a hot plate. After measuring out 2.1 grams of salicylic acid and 3 ml of acetic anhydride‚ we mixed the two together‚ along with 3 drops of sulfuric acid. We
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1. In the Luminol synthesis the compound being oxidized was the sodium hydrosulfite. 2. The purpose of the acetic acid is to pronate the dianon organic molecule to make the neutral organic compound‚ Luminol that will crash out of the solvent. If the number of moles were reversed for acetic acid and sodium hydroxide the solution would be very basic‚ and and the amount of Luminol produced would decrease. 3. The cold water was used to decrease the solubility of Luminol in the solvent and prevent further
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PRE-LAB The purpose of the lab is to determine the moles of hydrogen gas and then molar mass of the metal. First‚ the metal assigned to each group must be weighed out in order to ensure the hydrogen gas produced will not exceed the capacity for the gas measuring tube. Then‚ copper will be wrapped around the metal leaving 6-8cm at the end for a handle. The end wire will be bent into a hook to keep the sample at the bottom of the tube and increase the oxidation rate. A ring stand will need to be
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First‚ the synthesis of the coordination compound‚ KaFeb(ox)cdH2O‚ needed to be carried out. This was achieved by weighing out 8.29 grams of K2C2O4 with a Dial-a-gram balance. Once measured‚ the 8.29 grams K2C2O4 were placed in a 125 mL Erlenmeyer flask. 25 mL of deionized water were then added to the 125 mL flask and stirred with the K2C2O4 until complete dissolution was achieved. Next‚ 4.11 grams of FeCl3 were weighed out using the balance previously mentioned. Once the 4.11 grams were measured
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5.4. Synthesis of Poly L-Lactide (PLA) PLA was synthesized by the ring opening polymerization of L-Lactide in presence of stannous octoate. L-Lactide (1.44 g (0.01 mol)) was dissolved in 20 mL of toluene; 1.5 mg of stannous octoate was added to this solution. The
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Tie-Dye Grignard Synthesis Abstract: 4-Bromo-N‚N-dimethylaniline underwent a Grignard reaction with diethyl carbonate to produce a type of the tie-dye chemical triarylmethane. This specific triarylmethane produces a vivid crystal violet color when dyed. The experiment was first heated under reflux to produce the necessary Grignard reagent as a grey liquid. It was then reacted with diethyl carbonate and hydrochloric acid to produce crystal violet. The resulting chemical was very absorbent to
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Introduction: In this experiment‚ when vinyl strip and acetate strip is rubbed by tissue‚ it will charge the vinyl strip negatively and acetate strip positively caused by the transfer of electron between the strip and tissue. If molecules have non zero bond dipole‚ because polar molecule must have a non-zero molecular dipole where electron spend more of their time closer to one atomic nucleus than the other and make one end partially positive or negative than the other end. Different charge will
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