The objective of the present work was to formulate‚ characterize and optimize the preparations of hybrid nanoparticles containing dapsone which is finally converted into gel for topical drug delivery. The formulations were characterized for particle size‚ zeta potential and entrapment efficiency and were optimized by applying factorial design of experiment (23). The results showed that the optimal formulation (HN 4) of dapsone loaded hybrid nanoparticles had average particle size of 277nm‚ zeta potential
Premium Protein Acetic acid Chromatography
Today‚ aspirin is one of the most widely used medication on this Earth and has been since its popular breakout in the late 1890s. Long before we were born there was no such thing of a medication called aspirin. Instead‚ ancient people used willow leaves and bark from trees to help relieve oneself from pain and fevers. Aspirin as we come to know it in the form of an acetylsalicylic acid‚ was introduced to the world by Chemist Felix Hoffmann who was working at Bayer pharmaceutical company located in
Premium
EUROPEAN PHARMACOPOEIA 5.0 Acetylsalicylic acid TESTS Appearance of solution. Dissolve 1.0 g in 9 ml of alcohol R. The solution is clear (2.2.1) and colourless (2.2.2‚ Method II). Related substances. Examine by liquid chromatography (2.2.29). Prepare the solutions immediately before use. Test solution. Dissolve 0.10 g of the substance to be examined in acetonitrile for chromatography R and dilute to 10.0 ml with the same solvent. C. N‚N′-diacetyl-L-cystine‚ Reference solution (a).
Premium Sodium hydroxide Chromatography
Traumeel and Cortisone In the field of pain management‚ a common condition seen in patients are migraine headaches. According to The American Academy of Pain Management’s website‚ painmed.org‚ “When asked common types of pain‚ respondents of a National Institute of Health Statistics survey indicated that headache or migraine pain (15%).” One treatment used on all patients who continuously suffer from migraines is a cervical facet injection. .According to board-certified pain management specialist
Premium Paracetamol Inflammation Aspirin
Acetaminophen Abstract: The aim of this experiment is to prepare Acetaminophen (p-acetamidophenol)‚ an amide. Acetaminophen will be created by treating an amine (p-aminophenol) with an acetic anhydride. Color impurities present in the solid acetaminophen will be removed and then the decolorized product will be collected on a Büchner funnel for further purification by crystallization. Purity will then be determined by melting point. Introduction: Acetaminophen is commonly used as an analgesic to
Premium Melting point Yield Acetic anhydride
Generic Name | Brand Name | Classification | Mechanism of Action | Contraindication | Indication | Side Effects | Adverse Effects | Nursing Consideration | Mefenamic AcidDosage: 500 mg cap q 6 | Analmin | AnalgesicNon-SteroidalAnti-inflammatory | Mefenamic Acid has analgesic‚ anti-inflammatory and anti-pyretic properties. It is derivative of N-phenyl anthranili acid. Mefenamic acid shows central as well as peripheral analgesia. It is an inhibitor of cyclo-oxygenase. It also antagonizes certain
Premium Hypertension Myocardial infarction Peptic ulcer
Unit #1 – Ethics 1) Introduction of Vioxx a) Introduction in 1999 b) Withdrawal of the drug in 2004 due to heart attacks c) Merck’s knowledge of the effects of Vioxx and unethical decision to continue to sell the drug 2) Vigor Study d) Vioxx lessened stomach bleeding e) Results also showed higher risk of heart attacks f) Merck blamed naproxen for skewing the results against Vioxx 3) New England Journal of Medicine Omission g) Merck omits
Premium Coronary artery disease Aspirin Hypertension
-APPLICATION OF ENZYMES IN ORGANIC CHEMISTRY Why enzymes in organic synthesis? | Alternative to chemical methods: * High region- and stereoselectivity * Milder reaction conditions * Environmentally more friendly | Which enzyme(s)? | OxidoreductasesHydrolasesLyasesIsomerases | Which reaction system? | AqueousAqueous and water-miscible organic solventAqueous and water-immiscible organic solventPure organic solventOther solvents (supercritical fluids‚ ionic liquids) | Which ‘chemistry’
Premium Enzyme Amino acid Organic chemistry
some amount of intelligence built-in [1]. Speech synthesis system has wide range of applications in our daily life. Speech synthesis plays an important role in signal processing. The natural‚ intelligible synthetic voices in the expanding field of speech technology had a lot of demand [4]. Speech was the natural form of human communication. Automatic speech signal generation on computers is commonly called speech synthesis. Speech synthesis was the artificial production of human speech [2]. Speech
Premium Speech recognition
alternative to aspirin. Such a positioning will be able to attract current aspirin customers to Datril. The marketing campaign should focus on physicians‚ trade and patients. It should stress the information of little side effects compared to other analgesic medicine. Both the retail price and the trade price should be lower than Tylenol. Segmentation and targeting: Datril should target on aspirin users. Datril potential clients could be 1) people currently using aspirin 2) people currently
Premium Sanitary napkin Menopause Menstruation