Secondary excitotoxicity is thought to be more relevant to chronic neurodegenerative disorders than the classical acute form. In this pathway increased glutamate levels are not required as disturbances with the neuronal resting membrane potential cause glutamate receptors to be over-activated by physiological levels of glutamate. In a neuron which is affected by another pathological process and shows reduced ATP production‚ Na+ dysfunction or impaired glucose metabolism and as a result has an abnormal
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The movie Juno is fiction and came out in 2007. It is about Juno MacGuff a 16 year old high schooler who gets pregnant after her first time having intercourse with Paulie Bleeker‚ who is also in high school. Although 9 years old‚ this movie is still extremely relevant in today’s society in regards to teen pregnancy. It tackles all the different options one can take and how emotionally‚ physically‚ and mentally challenge this decision is‚ especially when you’re a teen. Psychologist David Elkind theorized
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The nonmutated form of DMPK functions in the production of protein kinase serine; this enzyme plays a role in intracellular communication and in the regulation of myosin phosphate. When DMPK is mutated‚ the proteins CUG-BP1‚ MBNL1 and INSR are displaced causing the splicing of troponin pre-mRNA which causes malfunctions in the cardiac conduction system‚ dominance of a chloride channel that causes myotonia‚ dominance of an insulin receptor that affects the sufficiency of insulin‚ and dominance of
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Introduction: The pharmacokinetics of a drug describes the journey of a drug through the body i.e. its absorption‚ bioavailability‚ distribution‚ metabolism and excretion. Opioids are substances (endogenous or synthetic)‚ which produce ‘opiate-like effects’. Opiates are alkaloids derived from the Papaver somniferum poppy e.g. Morphine‚ Codeine (a morphine-like agonist) and Methadone (a synthetic analogue of morphine) and are primarily used as analgesics.[1] Discussion: Morphine has a 4-ring structure
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purpose of a synthesis essay is to make insightful connections. Those connections can show the relationship(s) between parts of a work or even between two or more works. It is your job to explain why those relationships are important. In order to write a successful synthesis essay‚ you must gather research on your chosen topic‚ discover meaningful connections throughout your research‚ and develop a unique and interesting argument or perspective. A synthesis is not a summary. A synthesis is an opportunity
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Introduction The American Chemical Society databases were investigated through Scifinder Scholar Version X to find any information about Butyl 2-Cyano-(3‚5 dichloro-phenyl)-2-propenoate. There was no previous information present. Then‚ the microscale synthesis and characterization of Butyl 2-Cyano-(3‚5 dichloro-phenyl)-2-propenoate was conducted with the base catalyzed Knoevengael condensation of the butyl cyanoacetate and corresponding aldehyde (gkharas/235_14F/235_14F_Lab_2.pdf) and analysis. The elemental
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Protein Synthesis Worksheet 1. 2. a. Protein synthesis began in the nucleus. b. Chromatin is a diffuse mass located in the nucleus where genetic material is found. c. A gene is a sequence of nucleotides‚ it is important because they form the template and these templates are used for synthesizing proteins. 3. a. Transcription is the first step of protein synthesis it uses a sequence of DNA nucleotides to produce a sequence of RNA nucleotide. b. RNA polymerase bonds to RNA nucleotides together
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SYNTHESIS OF SILVER NANOPARTICLES AND ITS CYTOTOXIC EFFECT AGAINST THP-1 CANCER CELL LINE 1 * Department of Biotechnology‚ Modern College‚ Shivajinagar‚ University of Pune‚ Pune‚ India. Mrs Rebecca Thombre email rebecca.thombre@gmail.com Telephone 9822224957 020 400966725 ABSTRACT: Nanotechnology is a field of science which involves the synthesis and applications of nanoparticles. Silver nanoparticles (AgNp) have applications in various fields due to their unique
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0.22g (percent yield of 86.9%). The percent yield after recrystallization‚ was 80.9%. INTRODUCTION The goal of this experiment was the synthesis of 3-nitrochalcone from 3-nitrobenzaldehyde and acetophenone as shown in Figure 1: Figure 1: Synthesis of 3-Nitrochalcone from 3-Nitrobenzaldehyde and Acetophenone Source: cnx.org The mechanism for the synthesis of 3-nitrochalcone is presented in Figure 2. The alpha carbon on the acetophenone is deprotonated‚ followed by the attack of the alpha carbon
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Project #3: Explanatory Synthesis Paper Comic from: http://www.lapsura.com/drawings/archives/images/do-my-essay.gif REVIEW Chapter 4 WRAC (See Notes on Explanatory Summary below) For the academic explanatory synthesis paper you will read a minimum of three sources on the topic you choose. You can choose from three topics: ➢ Fairy Tales: A Closer Look at Cinderella: (Select three articles in textbook) See Syllabus/Calendar ➢ E-Mail Etiquette: (Select
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