Hello Shyam‚ Thank you for your informative post about iron-deficiency anemia. Anemia is not a disease but an indication of an underlying illness‚ in which there is a decreased in the number of the red blood cells (RBCs)‚ the amount of hemoglobin (Hgb)‚ and/or the volume of RBCs (Sabol et al.‚ 2010). As we age‚ Hgb levels decrease‚ increasing the incidence of anemia (Sabol et al.‚ 2010). Iron-deficiency anemia (IDA) is the insufficiency in iron dietary intake and/or in iron absorption from different
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Evolution of Disease Sickle Cell Anemia Sickle Cell Anemia is a disease that which the red blood cells form an abnormal sickle or crescents shape. Red blood cells are very important to the human body because they carry oxygen throughout the body. The main causes of Sickle cell is when the cells in the body mutate into abnormal cell called haemoglobin S. Haemoglobin S causes the red blood cells to become sickle shaped‚ rigid. This causes to make it more difficult for the cells to flow the vein
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Sickle cell anemia was first discovered in the year of 1910. A young man by the name Walter Clement Noel from the island of Grenada‚ studied in Chicago. He went to Dr. James B. Herrick‚ whom was a cardiologist‚ with symptoms of anemia‚ who assigned Dr. Ernest Irons to the case. There Dr. Irons noticed that Noel’s red blood cells were the shape of a sickle. Although sickle cell anemia has occurred in Africa for thousands of years‚ Dr. Herrick was the first to provide a formal description of sickle
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Sickle cell anemia (SCA) is a genetic disorder that is hereditary. It affects the blood‚ and is caused when the hemoglobin in blood cells are deprived in oxygen from the proteins. These cause normal round blood cells‚ to have are rigid sickle shape. People affected by SCA have a higher risk of death‚ stroke‚ severe attacks‚ and severe rushes of pain. James Herrick discovered an anemia‚ and found bizarre sickle-shaped cells in 1910. A treatment for the disease was discovered in the 1920s by E. Vernon
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Sickle Cell Anemia "An ISU student died March 12 from complications of Sickle Cell Anemia there is no cure for Sickle Cell Anemia" (Indiana Statesman‚ 2004). What is Sickle Cell Anemia? According to National Institute of Health‚ Sickle Cell Anemia is a lifelong‚ inherited blood disorder or disease‚ characterized primarily by chronic anemia and periodic episodes of pain. It is one form of sickle cell disease‚ a category of blood disorders caused by defective hemoglobin. Hemoglobin is a substance
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SICKLE CELL ANAEMIA Sickle cell anemia is an inherited condition. People with sickle cell anemia inherit two copies of the sickle cell gene‚ one from each parent. The sickle cell gene makes abnormal hemoglobin called Hemoglobin-S. The sickle cell gene is a trait due to a change in ONE nucleotide in the DNA sequence that leads to a change in ONE amino acid that changes how the hemoglobin protein folds. This change in the structure of the hemoglobin protein leads to a change in the shape of
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Alexandria Agee Ms. Songer AP Biology February 16 2015 Sickle Cell Anemia: Case Study Summary Sickle Cell Anemia is a painful diseases that is caused by a mutation in the protein called hemoglobin which helps carry oxygen in red blood cells. Because of the mutation‚ the hemoglobin is shaped oddly which results in pain because it is hard for the blood to travel throughout the body and anemia because of the lack of oxygen in the blood. A person can only have this disease if both parents are carriers
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Deficiency AnemiaWhat is it and what are its causes?Anemia is an insufficient amount of red blood cells in the bloodstream and iron deficiency anemia is where there is a lack of iron in the blood. You need iron in your blood to make hemoglobin‚ which contributes in distributing oxygen to tissues from the lungs. One of the most common causes of iron deficiency anemia is an inadequate intake of iron in your diet. Another possible cause of iron deficiency anemia is bleeding‚ be this because of an injury or
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Sickle Cell anemia is a group of inherited red blood cell disorders‚ or a collection of recessive genetic disorders characterized by a hemoglobin variant called Hb S. Normal red blood cells are round like doughnuts‚ and they move through small blood tubes in the body to deliver oxygen. Sickle red blood cells become hard‚ sticky and shaped like sickles used to cut wheat. When these hard and pointed red cells go through the small blood tube‚ they clog the flow and break apart. This can cause pain‚
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Pernicious Anemia and its association to orthostatic hypertension Pernicious anemia is the major form of vitamin B12 deficiency. It is caused by serum antibodies against intrinsic factor which leads to B12 deficiency rather than by B12 deficiency itself. Absorption of vitamin B12 requires intrinsic factor which is secreted by parietal cells. Pernicious anemia is marked by autoimmune attack on gastric mucosa and a loss in parietal cells. Approximately 75% of the affected patients have type I antibody
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