B I O L O G Y 130 INTRODUCTORY CELL BIOLOGY LECTURE NOTES Department of Biology University of Waterloo Fall‚ 2012 BIOL 130 LECTURE NOTES Fall‚ 2012 a Lecture Notes This booklet contains the notes that will be presented as part of the online modules. For copyright reasons‚ the figures that will be shown along with the notes cannot be reproduced. However‚ most of these figures come from the required course text‚ Cell and Molecular Biology: Concepts and Experiments‚ 6th edition
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Evolutionary Optimization of Protein Folding ´ ` ´ ¨ Cedric Debes1‚ Minglei Wang2‚ Gustavo Caetano-Anolles2*‚ Frauke Grater1‚3* 1 Heidelberg Institute for Theoretical Studies‚ Heidelberg‚ Germany‚ 2 Evolutionary Bioinformatics Laboratory‚ Department of Crop Sciences‚ University of Illinois‚ Urbana‚ Illinois‚ United States of America‚ 3 CAS-MPG Partner Institute and Key Laboratory for Computational Biology‚ Shanghai‚ China Abstract Nature has shaped the make up of proteins since their appearance‚
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Insights into Protein–DNA Interactions through Structure Network Analysis R. Sathyapriya.¤‚ M. S. Vijayabaskar.‚ Saraswathi Vishveshwara* Molecular Biophysics Unit‚ Indian Institute of Science‚ Bangalore‚ India Abstract Protein–DNA interactions are crucial for many cellular processes. Now with the increased availability of structures of protein–DNA complexes‚ gaining deeper insights into the nature of protein–DNA interactions has become possible. Earlier‚ investigations have characterized the
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an important biomaterial in many aspects. Numerous studies on chitin have focused on its biomedical applications. In this review‚ various aspects of chitin research including sources‚ structure‚ biosynthesis‚ chitinolytic enzyme‚ chitin binding protein‚ genetic engineering approach to produce chitin‚ chitin and evolution‚ and a wide range of applications in bio- and nanotechnology will be dealt with. Keywords: chitin; chitosan; chito-oligosaccharide; biotechnology; nanobiotechnology application;
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noncovalently bound a and b subunits‚ which pair to form heterodimers. There are 18a and 8b known subunits which combine to form at least 24 distinct integrin heterodimers (Hynes 2002). Each heterodimer consists of a large extracellular domain which binds proteins in the extracellular environment‚ a single-membrane-spanning transmembrane domain‚ and a generally M.B. Srichai and R. Zent (*) Department of Medicine‚ Cancer Biology and Cell Biology‚ Vanderbilt Medical Center‚ Nashville‚ TN‚ 37232‚ USA
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Food Intake 3-Days SCI/220 Food Intake 3-Days During my three day food intake I discovered that I only consumed 88 grams of protein. In these three meals I spent almost 40 dollars and I was short almost 100 grams of protein required for my weight. Four slices of pizza‚ and two double cheeseburgers produced the most protein. Oatmeal‚ beer‚ and coffee only counted for less than 10 grams. All six items consumed over the 3 day stretch accounted for carbohydrates. The items ranged from 10g
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1. What are antibodies and why are antibodies ideal for targeting? An antibody‚ also known as an immunoglobulin‚ is a large Y-shaped protein used by the immune system to identify and neutralize foreign objects such as bacteria and viruses. The antibody recognizes a unique part of the foreign target‚ termed an antigen.[1][2] Each tip of the "Y" of an antibody contains a paratope (a structure analogous to a lock) that is specific for one particular epitope (similarly analogous to a key) on an antigen
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cysteine peptidase; CTNNB1‚ catenin (cadherin-associated protein)‚ beta 1; CTS‚ cathepsin; EPCAM‚ epithelial cell adhesion molecule; LRP6‚ lipoprotein receptor related protein; LC3‚ microtubule-associated protein 1 light chain 3B; MTORC1‚ the mechanistic target of rapamycin complex 1; Nig‚ nigericin; PAS‚ phagophore assembly site; AO‚ acridine orange; RAB7A‚ member RAS oncogene family; ROS‚ reactive oxygen species; RPTOR‚ regulatory associated protein of MTOR‚ complex 1; Sal‚ salinomycin; TUBB‚ β-tubulin;
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attributed to its ability to act as a sequence-specific transcription factor to regulate expression of over one hundred different targets‚ and thus to modulate various cellular processes including apoptosis‚ cell cycle arrest and DNA repair. The p53 protein with its unique C- and N-terminal structures is rigidly modulated by several important biological processes such as phosphorylation‚ acetylation and ubiquitination‚ through which it effectively regulates cell growth and cell death. p53 mutations can
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“EXPRESSION‚ PURIFICATION AND QUANTIFICATION OF NEURAMINIDASE GENE OF INFLUENZA” A dissertation submitted to the VIT University in partial fulfillment of the requirement for the award of the degree of MASTER OF SCIENCE In BIOTECHNOLOGY SUBMITTED BY A. SRIKANTH Register No: 08MSBOO1 UNIVERSITY (Estd. u/s 3 of UGC Act 1956) VIT SCHOOL OF BIO SCIENCES AND TECHNOLOGY VIT UNIVERSITY VELLORE-632014 MAY 2010 DECLARATION I here by declare that the project work entitled “EXPRESSION‚PURIFICATION
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