Review Article p53: Structure‚ Function and Therapeutic Applications Ling Bai and Wei-Guo Zhu1 Department of Biochemistry and Molecular Biology‚ Peking University Health Science Center‚ Beijing‚ China [L. Bai‚ W.-G. Zhu]; Department of Biotechnology‚ Guilin Medical College‚ Guilin‚ China [L. Bai] Since the p53 tumor suppressor gene has been found to be mutated in more than 50% of human cancers‚ it has attracted the interest of numerous researchers. The capacity of p53 for multiple biological
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What is sciatica? It is the pain which affects the hip‚ back‚ leg and is produced by a pinched nerve root present in the lower back. This extremely painful condition may also be caused by deterioration of a bone. There are numerous reasons which can trigger sciatica which is no doubt quite traumatic and hurting. Some of the other common causes for sciatica are Spinal stenosis‚ Degenerative disc disease‚ not exercising regularly‚ Spondylolisthesis and sleeping on soft mattress. The symptoms which
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(1933) e 8. C. Beck‚ Roentgen Ray Diagnosis and Therapy (Appleton‚ London‚ 1904) 9 10. H.S. Kaplan‚ Basic principles in radiation oncology. Cancer 39(Suppl 2)‚ 689–693 (1977) 11 part dans le testicule‚ par le fractionnement de la dose. Compt. Rend. Soc. Biol. 97‚ 431–434 (1927) 12. H. Coutard‚ Principles of X-ray therapy of malignant disease. Lancet 2‚ 1–12 (1934) 13 o 409–413 (1913) 14. J. Campbell‚ Web site on Lord Ernest Rutherford‚ including a comprehensive bibliography at http://www.rutherford.org
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29‚ 1370–1374. Rudall‚ K.M.; Kenchington‚ W. The Chitin System. Biol. Rev. 1973‚ 48‚ 597–633. Minke‚ R.; Blackwell‚ J. The structure of [alpha]-chitin. J. Mol. Biol. 1978‚ 120‚ 167–181. Rinaudo‚ M. Chitin and chitosan: Properties and applications. Prog. Polym. Sci. 2006‚ 31‚ 603–632. Roncero‚ C. The genetic complexity of chitin synthesis in fungi. Curr. Genet. 2002‚ 41‚ 367–378. midgut of adult Aedes aegypti. Insect. Biochem. Mol. Biol. 2006‚ 36‚ 1–9. Cohen‚ E. Chitin synthesis and inhibition: a revisit
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Congress on National Parks and Protected Areas. Butler‚ R.W. (1993). Tourism-An Evolutionary Perspective. In J. G. Nelson‚ R. Butler& G. Wall(eds.) Tourism and Sustainable Development: Mornitoring. Planning‚ Managing‚ 26-43. Waterloo: Heritage Resources Centre‚ University of Waterloo. Butler‚ R.W. (1995). Seasonality in tourism: issues and problems in Seaton‚ A V et al (eds) Tourism: the State of the Art Wiley‚ London. Butler‚ R.W. (1998). Sustainable Tourism-looking Backward in Order to Progress? In
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Chapter 2 Integrin Structure and Function Manakan Betsy Srichai and Roy Zent Abstract Integrins are a large family of heterodimeric glycoprotein receptors first discovered over twenty years ago. They exist as two noncovalently bound a- and b- subunits that function as adhesion molecules and play key roles in many biological processes including actin cytoskeleton organization and transduction of intracellular signals regulating cellular functions. Integrins bind a variety of extracellular matrices
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RESEARCH IN MOTION MANAGING EXPLOSIVE GROWTH In the January of 2008‚ Research in Motion (RIM) is standing at the strategic juncture where important decisions need to be taken regarding global expansions. The biggest strategic issue it faces is to carry over yesteryears’ growth to next level through sustainable innovation at global level. Although its R&D expenditure has grown 6 times in the last four years‚ the ratio of R&D expenditure to sales has been halved. This ratio shows RIM is
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BIOL 130 Lab Report Identifying Two Macromolecules - Carbohydrates and Proteins 9/26/2013 [Type the company name] INTRODUCTION As the name suggests‚ macromolecules are large molecules that make up more than 90% of the total cell mass. These biological macromolecules vary greatly in size - from several hundred to several hundred million molecular weight units - and are made up of monomer units. There are four major classes of biological macromolecules: proteins‚ carbohydrates‚ lipids
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the essay’s main supporting points. Simple thesis statement: The Waterloo Campaign was a disaster for Napoleon. Three-part thesis statement: The Waterloo Campaign was a disaster for Napoleon because it destroyed the bulk of the French armed forces‚ exposed Napoleon’s personal weaknesses‚ and dramatically eroded his support among the French people. Good thesis statements State or name the central idea of the essay (The Waterloo Campaign) Assert something specific and important about the essay’s
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