The brain has a specialized vasculature that extends from the surface to deep within the brain tissue‚ reaching all regions in order to meet the brain’s high metabolic demands. Exposures to toxic compounds entering the blood have the potential to access this vasculature leaving the brain susceptible to possible neurotoxicity. Currently‚ there are over 200 known chemicals that have been correlated with neurotoxicity. A protective mechanism called the blood brain barrier (BBB) was first discovered
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There was always an idea that brain barriers‚ most specifically blood brain barrier‚ along with the blood cerebro-spinal fluid barrier‚ only had one role. This role was that they restricted the traveling of molecules in and out of the CNS‚ and that was it. However‚ scientists and doctors began wondering if barriers were really that simple. They then decided to perform some research on these barriers and found that neuroscience and brain barrier science are linked in several ways. One of the first
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Astrocytes help form the blood brain barrier. The blood brain barrier prevents harmful materials from moving out of the bloodstream and into the brain. It helps maintain an ion gradient and is important in the transport of materials into and out of the brain. Its endothelial cells contain many tight and adherens junctions‚ which make the endothelial cells of these capillaries tighter than in other places in the body. Astrocyte feet are in physical contact with the capillary endothelial cells. In
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How will you explain an adverse effect on a patient? How is this different that a side effect? Blood flow to tissues - The heart‚ liver‚ kidneys‚ brain‚ and lungs are rapidly perfused tissues and are exposed to drugs in the first minutes following absorption. Muscle and skin are less rapidly perfused tissue‚ bone and fat are poorly perfused tissue and are exposed to drugs at the final distribution. Binding of drug to plasma protein - the only free drug can diffuse to the site of action. Reservoir
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dangerous and what kind of damage it they can do to people. There was a case on a man who blamed cell phones in the hospital that had died from a brain tumor. That person blamed the death of their family member on cell phones because the cell phone was right beside where the brain tumor was. Scientists were investigating on how can the cell phone can cause brain tumors and other serious diseases. Some scientists say that cell phones are giving off radiation when talking on the phone. Cell phones are like
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While Waiting: A Prenatal Guidebook‚ it is stated that aspartame is suspected of causing brain damage in sensitive individuals. A fetus may be at risk for these effects. Some researchers have suggested that high doses of aspartame may be associated with problems ranging from dizziness and subtle brain changes to mental retardation. Cancer (Brain Cancer) In 1981‚ an FDA statistician stated that the brain tumor data on aspartame was so "worrisome" that he could not recommend approval of NutraSweet
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Diagnostic Barriers to success in college When attending college withers a new student or old‚ there will be barriers in the way. These roadblocks can appear in various ways during a student’s career in college. The barriers can be anything from money‚ or attendance‚ and even time management. The key is to recognize the walls and overcome them to succeed. First‚ issue for many students is money. It’s not cheap to attend college‚ but colleges have many ways of helping out their students. One
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The Nutty Professor and Brains‚ Brains‚ Brains By Jana Gilbert “Hello‚ class!” Professor Dobbins spoke enthusiastically as the last student entered the room. Today‚ he was going to talk about his favorite part of the human anatomy: the brain. “Today is going to be exciting!” All of the students groaned. They knew that when he said something would be “exciting‚” it was always boring. Always. “How many of you know what the Ancient Egyptians believed about a person’s behavior? Who controlled
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Trying to listen to more than one conversation at a time‚ this includes having the television or radio on while attempting to listen to somebody talk; being on the phone to one person and talking to another person in the same room and also being distracted by some dominant noise in the immediate environment. You find the communicator attractive/unattractive and you pay more attention to how you feel about the communicator and their physical appearance than to what they are saying. Perhaps you simply
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Brain tumors are abnormal growth of tissue in the brain or spinal cord. This abnormal growth disrupts the normal functions of the brain. Brain tumors are categories based on where they originated and whether they are cancerous or noncancerous. They can be benign which means they do not contain cancer cells‚ they grow slowly‚ and do not spread into other tissue. The tumors can also be malignant‚ which means they contain cancer cells and spread rapidly into surrounding tissue. ("Brain Tumors") Surgery
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