he backbone (vertebral column) is the central axis of the skeleton. It extends from the base of the skull to the bottom of the pelvis. It consists of 26 individual bones grouped into five separate regions; The vertebrae‚ twelve thoracic vertebrae‚ five lumbar vertebrae‚ one sacral bone and one coccygeal bone. (Cinnamon L. VanPutte‚ Jennifer L. Regan‚ Andrew F. Russo‚ McGraw-Hill‚ 2010.) The Vertebral column also host major curvatures; The sacral and thoracic both concaving anteriorly and the lumbar
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mouse by swapping an scf gene with gfp. Scf gfp/gfp homozygous mice died perinatally and were found unable to regenerate blood cells. Scf gfp/+ mice demonstrated GFP expression primarily by perivascular cells surrounding sinusoids throughout the bone marrow (Fig.1h-m). Through gene expression profiling‚ ding and his team found that Scf-GFP+ cells form a perivascular niche for the HSCs. In order to determine whether Scf is necessary and required by adult hematopoietic stem cells‚ Scf expression
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_________ blood contains anti-A antibodies. a. Type A b. Type B c. Type AB d. Type O Which abnormality is characteristic of multiple myeloma? a. Overproduction of immunoglobulins b. Overproduction of erythrocytes c. Underproduction of bone marrow d. Underproduction of calcium An inherited defect in the ability to produce hemoglobin due to the decrease synthesis of globin is: a. Aplastic anemia b. Pemicious anemia c. Sickle cell anemia d.
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In an allogeneic transplant stem cells are collected from a donor‚ related or unrelated to the patient‚ then transplanted into the patient. Stem cells can be collected in two different ways. One way is via bone marrow and the other is via peripheral blood. The donor’s or patient’s bone marrow is collected from the pelvis‚ femur or sternum‚ though the pelvis is the most common‚ and then infused into the patient via a central line. In a peripheral blood stem cell collection the donor or the patient
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Immune System The organs of our immune system are located all throughout our bodies. The main organs of the immune system are bone marrow‚ the thymus‚ the tonsils‚ the spleen‚ and the lymph nodes. Bone marrow is the soft tissue that is found inside of most of our bones. Every cell of the human immune system originate from stem cells in the bone marrow. The bone marrow then goes through a process called hematopoiesis‚ which produces B-lymphocytes (B-cell)‚ immature thymocytes‚ red blood cells‚ white
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pneumonia b. Coccal – bacterium c. Vaccination – vaccine‚ a preparation of weakened or killed pathogen cells injected to produce antibodies 3. Peripheral Blood Stem Cell Transplantation – stem cells from blood are used in bone marrow transportation‚ helps to restore the bone marrow in order that the patient can
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ENC1102 WK 3 February 2‚ 2013 What is plasmacytoma and multiple myeloma? Plasmacytoma is a cancer where abnormal plasma cells called myeloma cells form a tumor in the bone. Multiple myeloma is when you have more than one tumor. Multiple myeloma is a rare and life-threatening cancer of the bone marrow. When my husband was diagnosed with plasmacytoma in February of 2011‚ we were told that multiple myeloma was not hereditary‚ and his mother passed from multiple myeloma in 2005. After
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Shawn Johnson Mrs Saltsburg Human Anatomy 4-07-2013 Skeletal Disorders Leukemia: The condition of leukemia is when your bone marrow starts making abnormal white blood cells. Some of the symptoms include fever‚ headaches‚ joint pain‚ swollen spleen‚ and losing weight. To be diagnosed with leukemia‚ your white blood cells would be a high level and all the other blood cell levels would be lower then normal. The treatment for leukemia is chemotherapy( which uses medicine to kill the cancerous cells
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Sickle Cell Anemia Sickle cell anemia is an inherited blood disease. The word anemia is defined as meaning that the blood does not have the required number of red blood cells. These cells take on a crescent shape‚ which is where the disease takes its name from the abnormal sickle shapes of the cells. It is commonly found in people from Africa‚ the Mediterranean region‚ southern India and the Middle East. “This disease of the blood was first discovered in 1910 in a black college student from the
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Non-Hodgkin’s Lymphoma is a cancer of the lymphocytes the white blood cells. The lymphocytes and lymph system are essential in our body’s immune protection. It is an abnormal growth rate of these cells. Since lymph is found throughout the body it is easily spread from one area to another. In 2008 there were over 66‚000 new cases and just over 19‚000 deaths from it (cancer.gov). It is categorized as slow growing or fast growing‚ as well as if it starts in the T-cells or the B-cells. Lymphomas from
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