BROMINATION OF ACETANILIDE OBJECTIVE Aim of the experiment was too brominate acetaldehyde to form p-bromoacetanilide. INTRODUCTION Acetanilide is a chemical compound with the chemical formula of C6H5NH(COCH3). It is a crystalline solid that is prepared by acetylation of analine and is widely used in the dye industry. This crystalline solid is an odourless solid chemical that has a flake or leaf like appearance. It is also known as N phenylacetamide‚ acetanil or acetanilide. Its former
Premium Acetic acid Oxygen Ethanol
Bromination of Acetanilide Objective: The objective of this experiment was to use melting point and NMR to determine which of two isomers‚ ortho or para‚ would most likely form after brominating Acetanilide through electrophilic aromatic substitution. Procedure/Observations: 1. Weigh out ~280 mg of acetanilide in a 10 mL r.b. flask with a stir bar. 2. Then‚ add 2.0 mL of glacial acetic acid using a calibrated Pasteur pipet. 3. Stir the mixture until all of the acetanilide has dissolved
Premium Stoichiometry Ethanol Oxygen
Bromination of Acetanilide Introduction: Bromination of acetanilide to 4-bromoaniline was studied in this experiment. One of the most important mechanism with the reaction of aromatic compounds is the electrophilic aromatic substitution reactions(wade‚2013). The electrophilic aromatic substitution enable scientists to make substituted aromatic compounds. However‚ substitution groups affect the electrophilic substitution mechanism. A nitrogen atom attached to hydrogen is learned to be a powerful
Premium Chemical reaction Chemistry Organic reaction
Lab 3: Bromination of Acetanilide CHEM 2110 Hassan Alsaleh 0525970 Due date :11/02/2015 Q1: To find the limiting reagent we need to find the number of moles of acetanilide‚ and the number of moles of Bromine. Mass of Acetanilide used = 0.67g Molar mass of Acetanilide = 135.16g/mol[1] Number of moles of Acetanilide = (0.67g) / (135.16g/mol) = 0‚005 mols Volume of Bromine = 0.25ml Density of Bromine = 3.103 g/ml[2] Mass of Bromine = (0.25ml) X (3.103g/ml) = 0.78g Molar mass of Bromine
Premium Stoichiometry Yield Oxygen
Synthesis of Acetanilide By: Rick Whitely April 9‚ 2013 Organic Chemistry Lab 1; Professor J. Hutchison Recrystallization is a common method of purifying organic substances through the differences in solubility at different temperature. In this experiment‚ acetanilide was produced by acetylation of aniline with acetic anhydride. The crude acetanilide was dissolved in a solvent in a heated water bath. The solution was cooled slowly in an ice bath as crystals form out. As the compound crystallizes
Premium Amine Oxygen Acetic acid
Greener Brominations Abstract In this experiment‚ trans-stilbene was brominated and debrominated with the use of three methods: bromination with pyridinium tribromide‚ bromination with hydrogen peroxide and hydrobromic acid‚ and debromination with zinc. The yields of parts A‚ B‚ and C are as follows: 68.6 %‚ 54.6 %‚ and 55.9 %. Introduction In the chemical process of bromination‚ an alkene is halogenated with bromine. Solvents that are typically used include methylene chloride and carbon
Premium Acid Oxygen Solvent
Synthesis of Acetanilide Reaction O NH2 + H3C C O O C CH3 O N C CH3 H + H3C O C OH Aniline Acetic anhydride Acetanilide Acetic acid Purpose: Acetanilide is a useful precursor to many pharmaceuticals such as acetaminophen and penicillin. Experimental Procedure. (Estimated time: 1.5 h.) Unless otherwise noted‚ all manipulations should be done in the chemical fume hood. Place 100 µL of aniline into a tared 10 X 75-mm test tube (standing in a small beaker or Erlenmeyer flask). Now add
Premium Acetic acid Laboratory glassware Oxygen
Learning Activity 1 Preparation of Acetanilide Abstract Recrystallization is a common method of purifying organic substances through the difference in solubility at different temperature. In this experiment‚ acetanilide was produced by acetylation of aniline with acetic anhydride. The crude acetanilide was dissolved in a solvent in a heating water bath. The solution was cooled slowly in an ice bath as crystals form out. As the compound crystallizes from the solution‚ molecules of other compounds
Premium Learning Education Management
CHEMISTRY 220 PRACTICAL REPORT PRACTICAL 1 Title: Nitration of Acetanilide Aim : To observe how an Aromatic electrophilic Substitution reaction takes place via the nitration of Acetanilide i.e. how hydrogen on a carbon chain is replaced with a nitro group. Reagents and Chemicals: • Acetanilide (5g) • Glacial acetic acid (5mL) • Concentrated sulphuric acid (10mL &1.5mL) • Concentrated Nitric acid (2.0mL) • Methanol (30-50mL) Modification to experimental
Premium Sulfuric acid Electrophilic aromatic substitution Oxygen
Bromination Solo Experiment 3 – Individual Lab Report (Save as pdf and submit‚ due by 12:00 NOON one week after experiment) Last Name: First Name: TA Name: Date Lab Performed: Date Lab Submitted: Group A‚ B‚ or C: Comments for Grading TA: (Please indicate if you performed the lab on a day other than your regularly scheduled day and/or with a TA other than your regular TA). Page Limit: report must not exceed FIVE pages (including this page) LIMIT DOES NOT INCLUDE ANY GRAPHS‚ SPECTRA
Premium Carbon Oxygen Chemical reaction