146 Fall-11 Organic Chemistry Midterm Report 13 October 2011 Table of Contents Separation of Benzoic Acid and Acetanilide 3 Extraction and Purification of Caffeine from Tea 4 Extraction of Trimyristin from Nutmeg 5 Conversion of t-butanol to t-butyl chloride 6 Appendix 7 Calculations 8 Literature and Experimental Values of Benzoic Acid and Acetanilide 9 Experimental Caffeine IR 10 Literature Caffeine IR 11 Experimental Trimyristin IR 12 Literature
Premium Distillation Caffeine
Alkene addition: Bromination of (E) Stilbene Introduction: In this lab we used the greener approach‚ which involves the addition of bromine across a double bond. When bromine reacts with E-stilbene (trans-1‚2-diphenylethene)‚ two new chiral carbons are created from the sp2 carbons‚ therefore 3 different dibrominated stereoisomers are possible: meso-(1R‚2S)‚ or the raceminc mixture-(1R‚2R) or (1S‚2S)-dibromo-1‚2-diphenylethane (Gilbert‚ 2010). When the bromination ion intermediate proceeds
Premium Carbon Melting point Stoichiometry
Q: Which of the ff are branches of the aortic arch? A: Brachiocephalic‚ left common carotid‚ left subclavian Q: Which of the ff are branches of the subclavian arteries? A: thyrocervical‚ internal thoracic‚ and vertebral artery Q: Where is the carotid sinus located? A: Base of the internal carotid Q: Which of the ff are branches of the internal carotid? A: middle cerebral‚ anterior cerebral‚ ophthalmic artery Q: The gastroduodemal artery is a branch from which artery? A: Common hepatic artery
Premium Heart Coronary circulation
al Chain Reactions: Bromination of Arenes Introduction The purpose of the bromination of arenes was to determine the different reactivities of different hydrocarbons with different hydrogen atoms when reacted with bromine under free-radical substitution. The time it took for the bromine color to disappear was used to determine the order of reactivity of the different hydrocarbons. Data and Results The data of the 10 hydrocarbon tubes and the 2 control tubes with bromine and dichloromethane in
Premium Carbon Functional group Hydrogen
Abstract The bromination of trans-cinnamic acid was completed to determine dibromide’s stereochemical structure and its mechanism. After the addition of bromine to trans-cinnamic acid‚ the product was identified by its melting point and infrared spectrum resulting in erythro-2‚3-Dibromo-3-phenylpropanoic acid after comparing similar properties. Introduction In this lab‚ the bromination of trans-cinnamic acid was completed to determine dibromide’s stereochemical structure‚ and from there determine
Premium Solvent Acetic acid Ethanol
Synthesis of p-Nitroacetanilide (electrophilic aromatic substitution) In this experiment‚ we convert acetanilide to p-nitroacetanilide. [pic] The mechanism for the nitration is that of electrophilic aromatic substitution. The nitronium ion is directed to the positions ortho and para to the acetamido (-NHCOCH3) group. This occurs because the resonance electron-releasing effect of that group increases the electron density at those positions‚ helping to stabilize the intermediates that
Premium Sulfuric acid Nitric acid
BroIn this experiment of the relative rates of free-radical chain bromination‚ we were expected to be able to determine the relative reactivates of the many types of hydrogen atoms involved toward bromine atoms. Bromination is defined to be a regioselective reaction meaning bromine has preference of making or breaking a bond over all other directions that it may have had available. In this case‚ Markovnikov’s rule is revealed to be the case in this situation that states that adding a protic acid
Premium Chemistry Acid Oxygen
University of Santo Tomas Faculty of Pharmacy Organic Chemistry Laboratory RECRYSTALLIZATION OF ACETANILIDE USING WATER AS SOLVENT Lagarteja‚ M.C.B.; Lim‚ H.G.N.; Lizo‚ K.J.R.; *Macalino‚ M.D.L.; Macapala‚ C. 2D-Pharmacy‚ Faculty of Pharmacy‚ University of Santo Tomas Abstract Recrystallization is a technique used to purify organic solids. This method involves dissolving of a solute in a solvent and inciting the solute to produce a precipitate from a solution. In this experiment‚ acetic
Premium Solvent Solubility Temperature
Purifying Acetanilide by Recrystallization Results: Acetanillide Solubility of acetanilide in water is 5.5g/100mL at 100C 0.53g/100mL at 0C PERCENT YIELD/THEORETICAL YIELD: Discussion: Acenatilide is a synthetic organic compound introduced in therapy in 1866 as a fever-reducing drug. Its effectiveness in relieving pain was discovered soon thereafter‚ and it was used as an alternative to aspirin. The solvent that I selected to recrystallize the
Premium Solvent Water Solubility
Hydrocinnamic acid underwent bromination using N-bromosuccinimide and AIBN. As one lab partner set up the reflux apparatus‚ the other measured the chemicals used in the lab experiment. 2.10 g of hydrocinnamic acid was used. It was observed as white and had a slight cinnamon smell. The amount of NBS was 2.49g and was measured in the fume hood. AIBN was measured at .030 g. 10 mL of acetic acid was also obtained. The reflux apparatus consisted of a 25 mL flask with a stir bar in a water bath. The chemicals
Premium Chemistry Water Sodium hydroxide