In the first part of this experiment acetic anhydride was used to prepare acetanilide which could then be readily brominated to form a mono-brominated product‚ with the bromine positioned at either the ortho‚ meta or para position on the aromatic ring. Acetic anhydride is very reactive towards nucleophiles and this reactivity is the result of the difference in electronegativities of the carbon and oxygen atoms that are bonded in acetic anhydride. This difference in electronegativities causes one
Premium Oxygen Atom Electric charge
Preparation u Alcohols when heated in presence of H2SO4‚ H3PO4‚ P2O5‚ Al2O3 or BF3 undergo loss of water molecule with the formation of alkene. Conc. H2SO4 180oC H3PO4/P2O5 200oC Al2O3/BF3 350oC CH3-CH=CH2 + H2O CH3-CH2-CH2-OH CH3-CH=CH2 + H2O CH3-CH=CH2 + H2O u u Mechanism: In the first step OH group of the alcohol is protonated in a fast reversible reaction. Unlike OH group‚ protonated OH group is a good leaving group. Step 1: CH3 CH3-C-CH3 + H+ HO CH3 CH3-C-CH3 H2O+
Premium Alcohol Alkene
Second step: rxn of the Grignard reagent with acetophenone‚ quenching with ammonium chloride Isolation of the product‚ identification Possible or actual sources of error Part one of our experiment consisted of the preparation of phenylmagnesium bromide from bromobenzene. PhMgBr is an organometallic reagent‚ a class of nucleophile known as a Grignard reagent. Gringard reagents are a class of extremely reactive chemical compounds used in the synthesis of hydrocarbons‚ alcohols‚ carboxylic acids‚ and
Premium Magnesium Chemistry Diethyl ether
Buffers‚ and pH‚ and Diffusion oh my The pH of a solution is the measure of the concentration of charged Hydrogen ions in that given solution. A solution with a pH lower than seven is considered to be acidic. A solution with a higher pH is a base. It is very important for organisms to maintain a stable pH. Biological molecules such as proteins function only at a certain pH level and any changes in pH can result in them not functioning properly. To maintain these constant pH levels‚ buffer solutions
Premium PH Buffer solution Hydrochloric acid
recrystallized from methanol‚ yielding 0.128g of pale yellow crystals with a melting point of 131-135 oC. This represents 0.33% of the original mass of the two yolks. The cholesterol was then dissolved in ether and further purified by bromination with a bromine/acetic acid reagent and debromination with zinc powder‚ a series of aqueous washes‚ and a final recrystallization from methanol. Here‚ a yield of 28% was recovered from an initial mass of 100 mg of recrystallized material. The melting point of the
Premium Distillation Egg yolk Alcohol
* The halogens can be found on the left-hand side of the noble gases. * These five toxic‚ non-metallic elements make up Group 17 of the periodic table and consist of: fluorine (F)‚ chlorine (Cl)‚ bromine (Br)‚ iodine (I)‚ and astatine (At). * Although astatine is radioactive and only has short-lived isotopes‚ it behaves similar to iodine and is often included in the halogen group. * Since the halogen elements have seven valence electrons‚ they only require one additional electron to form
Premium Periodic table Chemical element Chlorine
The E2 reaction performed began by dehydrohalogenating the 3-chloro-3‚ 7-dimethyloctane with potassium hydroxide in aqueous ethanol. The 3-chloro-3‚ 7-dimethyloctane will lose a hydrogen from three different carbons that cause the formation of three constitutional isomers. If the hydroxide ion attacks a hydrogen on the 3-methyl carbon‚ then 2-ethyl-6-methyl-1-heptene will be the product. If a hydrogen on the carbon-2 was attacked‚ then the product would be 3‚ 7-dimethyl-2-octene. If a hydrogen was
Premium Chemical reaction Oxygen Hydrogen
seven minutes from start to finish. First‚ via intravenous lines‚ sodium thiopental is inserted into the body’s system. It is an anesthetic that numbs the entire body and that only last a couple of minutes under normal conditions. Next‚ pancuronium bromide is injected‚ paralyzing all of the body’s muscles‚ including facial
Premium Lethal injection Capital punishment
sample in test tube+ 1 drop dilute neutral KMnO4‚ if NO DECOLORIZATION warm mixture. Primary Alcohol( carboxylic acid Secondary Alcohol( ketones Tertiary( none Phenols Reaction with bromine/water (Confirms if phenol compound) Reagent: bromine in H2O Observation: Disappearance of orange-brown bromine color‚ then formation of white precipitate Procedure: 3 drops phenol soln on test tube+ Br in H2O drop by drop while shaking‚ observe formation of ppt Oxidation by KMnO4 (Confirms if phenol
Premium Carboxylic acid Alcohol Amine
variety of specialty chemical products. The company acquired Octel Associates‚ a tetraethyl lead (TEL) producer for its capacity to produce bromine. Though Octel used the chemical to make the additives‚ Great lakes used them in other products. The focus was on the TEL"gold mine" that Octel provided. The company was willing‚ in order to get the bromine-producing capability‚ to take on the last years of production of lead additives as well as an ethical and public relation challenge. This
Premium Gasoline Lead