G Model JMG-5899; No of Pages 17 Journal of Molecular Graphics and Modelling xxx (2009) xxx–xxx Contents lists available at ScienceDirect Journal of Molecular Graphics and Modelling journal homepage: www.elsevier.com/locate/JMGM Genome wide analysis and comparative docking studies of new diaryl furan derivatives against human cyclooxygenase-2‚ lipoxygenase‚ thromboxane synthase and prostacyclin synthase enzymes involved in inflammatory pathway P. Nataraj Sekhar a‚ L. Ananda Reddy a
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Wander through the Louvre‚ leaf through the "Great Books"--you won’t find many works by women. Feminists have long sought to explain this absence‚ and to question the standards that guide "canon formation"--the aesthetic judgments deem some works excellent‚ and others minor or altogether unworthy of notice. In her 1928 A Room of One’s Own‚ Virginia Woolf explored the social constraints that limited women’s literary and artistic production. Talent‚ even genius‚ counted for little‚ Woolf mused‚ without
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Introduction The use of anti-inflammatories is widespread in the treatment of musculoskeletal injuries and pain (Paoloni et al. 2009). This has in part led to the common misconception that inflammation is an inherently negative occurrence which needs to be stopped or at least limited rather than the essential healing process that it is (Garnham‚ 2009). In this case study the use of anti-inflammatories for a common musculoskeletal complaint will be discussed with the impact on the prescribing clinician’s
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Robert Browning The Pied Piper of Hamelin “What are the ways in which Browning tells the poem The Pied Piper of Hamelin?” The Pied Piper of Hamelin is set in medieval Germany‚ in a small town‚ Hamelin. The town is plagued by rats when a stranger‚ the Pied Piper‚ comes to town and offers to get rid of them if they Mayor will pay him. He plays bewitching music on his pipe which causes the rats to follow him. He leads the rats to the river and they drown. The Mayor breaks his promise and refuses
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encountered the setting up of Reserve Police Battalion 101. Further‚ Browning describes the particular effect this establishment had on him. “Though I had been studying archived documents and Holocaust court record for nearly twenty years‚ the impact this indictment was extremely powerful and disturbing. Never Before had I seen the monstrous deeds of the Holocaust so starkly set side by side with the human face of the killers” (Browning‚ xvi). This made him to write the book Ordinary Men: Reserve Police
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with the brief phrase ’I am here’‚ emphasising the setting of the laboratory which is in such sharp contrast to the church. The phrase ’Grind away’ at the start of the third stanza shows the woman’s eagerness for the chemist to make the poison. Browning brings the description alive by using alliteration in the phrases ’moisten and mash’ and ’Pound at thy powder’. The narrator is not in a hurry and says she would rather watch the concocting of the poison than be dancing at the King’s court. In the
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Elizabeth Barrett Browning was an social and political activist for many things‚ but most of all children’s rights. During the Victorian Age‚ Britain became the first industrialized country on the world. Much of the work was in coal mines and factories‚ causing long hours and hard labor. During this time period child labor laws did not exist and majority of the time they were put to work‚ especially if the family had several mouths to feed. (Mattord) The 1842 Royal Commission reports is where Elizabeth
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CLINICAL PROBLEMS A 26-year-old woman comes to an allergy clinic complaining of a runny nose and itching eyes. The symptoms become particularly severe during the spring months. She has tried over-the-counter antihistamines and they help reduce the symptoms‚ but also cause side effects that she finds intolerable. 1. Which of the following drugs would you not recommend? A. Cetirizine B. Desloratadine C. Diphenhydramine D. Fexofenadine E. Loratadine A 45-year-old man is to undergo
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Prostaglandin E2 EP3 receptor regulates cyclooxygenase-2 expression in the kidney Carlos P. Vio‚ Mariana Quiroz-Munoz‚ Catherina A. Cuevas‚ Carlos Cespedes and Nicholas R. Ferreri Am J Physiol Renal Physiol 303:F449-F457‚ 2012. First published 23 May 2012; doi: 10.1152/ajprenal.00634.2011 You might find this additional info useful... This article cites 55 articles‚ 29 of which you can access for free at: http://ajprenal.physiology.org/content/303/3/F449.full#ref-list-1 This article has been cited
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#1Reflection on "My Last Duchess"The speaker is notably a snobbish‚ childish‚ and indifferent Duke. He does not seem to have any remorse for his murder of his "Duchess" and remains arrogantly steadfast to his justification that his murder was for the cause of her (the Duchess’s) "too soon made glad" by other men‚ and her smiles to everyone who passed. He describes her as if she was just another distant thing in the past‚ and disregards the painting of her as just another piece of artwork. The poem
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