Targeting unmet needs in the treatment of cancer/ hematological malignancies through innovative drug development strategies have witnessed favorable outcomes. Over the past decade‚ Proteasome inhibitor‚ Velcade (bortezomib) and the immunomodulatory drugs – Thalomid (thalidomide) and Revlimid (lenalidomide) have become the cornerstone of treatment for patients with Multiple Myeloma (MM) resulting in improved survival. However‚ eventually all patients relapse and new treatment options for Relapsed/
Premium Thalidomide Multiple myeloma
PLC. POLLUTER POLLUTER MARINE OIL POLLUTION MARINE OIL POLLUTION Crude oil around 50‚000 liters (420 barrels) spilled into the sea from a pipeline unloading an oil tanker around 20 kilometers (12 miles) off the coast of Rayong province at Ao Prao‚ Samet (Thailand). Crude oil around 50‚000 liters (420 barrels) spilled into the sea from a pipeline unloading an oil tanker around 20 kilometers (12 miles) off the coast of Rayong province at Ao Prao‚ Samet (Thailand). POLLUTANT POLLUTANT
Premium Oil spill Petroleum Thailand
The Current Position of the Textile Industry in Bangladesh Today‚ the textile industry of Bangladesh can be divided into the three main categories: the public sector‚ handloom sector‚ and the organized private sector. Each of these sectors has its advantages and disadvantages. Currently‚ the organized private sector dominates‚ and is also expanding at the fastest rate. Public Sector The public sector is that portion of the industry controlled by organizations that are part of the government
Premium Textile manufacturing Textile Cotton
America The United States imported about 229 billion cubic feet of LNG in 2002‚ accounting for 4 percent of world’s LNG trade (http://www.eia.doe.gov/). LNG is received by pipeline from Canada and through shipments from Trinidad‚ while the Canadian gas market imports gas from US to Canadian eastern market through pipeline. Trinidad has now overtaken Algeria who was US largest supplier of LNG. As one of the primary sources of LNG supply‚ it now servers US with 66% of the nations LNG imports.
Premium Natural gas Liquefied natural gas
II‚ the Allies needed a steady and reliable supply of petrol (gasoline) for their armor (tanks and armored vehicles)‚ trucks‚ and airplanes. After months of work‚ they had a concrete strategy‚ Operation PLUTO (PipeLines Under The Ocean); a plan to build the first major undersea pipeline to transport massive amounts of fuel across the English Channel. The fuel would be used to supply the Allied Armies with the much needed fuel for military offensives in the European Theater after D-Day. The project
Premium World War II United States World War I
Juvenile detention centers were officially established in the United States in 1898 in Chicago‚ Illinois. Before this‚ minors were tried as adults in the criminal justice system. This change was founded on the two basic principles that minors should not be expected to receive the same punishments as an adult would‚ because they have not fully developed‚ and that the court system should focus on rehabilitation for the young children. The juvenile detention system established‚ was supposed to be quite
Premium Crime Criminology Juvenile delinquency
aggregate throughput than commercially available shared-memory soft multi-processors via improvements to the underlying soft processor architecture. We study a number of processor pipeline organizations to identify which ones can scale to a larger number of execution threads and find that tuning multithreaded pipelines can provide compact cores with high throughput. We then perform a design space exploration of multicore soft systems‚ compare single-threaded and multithreaded designs to identify scalability
Premium Central processing unit Transmission Control Protocol Computer network
as one of the “ten worst corporations” during the year 2001 and 2006. In fact‚ BP and its competitors Royal Dutch-Shell were considered by activists to be responsible with the threatening phenomenon of climate change. BP was warned before the oil pipeline leak happened in Alaska‚ but no action was made by the higher officials to mitigate its possible occurrence and reduce damages. In March 2005‚ BP ’s Texas City‚ Texas refinery‚ one of its largest refineries‚ exploded causing 15 deaths‚ injuring
Premium Risk management Risk Operational risk
R SI DDI K ( 12 400036 3 3 ) VI TA HEL I A DESY ( 12 40002 78 2 ) Table of Content 2 Background Business & Industry Backround Sony Eye Toy Product Analysis Concept Development Marketing Strategy Market Performance Product Development Pipeline Future of EyeToy $62 billion annual sales (2004) • Sony Computer Entertainment Inc. (SCEI) led the development of PlayStation since 1994 • In 2000‚ PlayStation 2 (PS2) was launched • As of 2004 PlayStation 2 had reached 70 million units
Premium Sony Computer Entertainment Marketing
1. Until recently‚ the idea of parenthood was not vastly different from that of motherhood. This is because parenthood affects men and women’s careers in different ways. Motherhood is associated with less prestigious careers and lower income‚ while fathers see little to impact of parenthood on their careers. The reason for this lies in the different ways in which society perceives motherhood and fatherhood. It is almost always understood that motherhood will become an obstacle in a woman’s career
Premium Tenure Woman Mother