Daclizumab (Biogen Idec and Abbott Biotherapeutics Corp.) is a humanized mAb acting as a blocker of the α-subunit (CD25) of the high-affinity IL-2 receptor [19]. IL-2 is secreted by activated lymphocytes and stimulates production of other proinflammatory cytokines while it is also involved in lymphocytic proliferation. Daclizumab was initially approved for the prevention of renal allograft rejection as part of a combination regimen and evidence was progressively accumulated showing that this drug
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Since the immaterial misstatement will not have a direct effect on financial statements and thus will not affect people’s decision related to the financial statements‚ the auditor can appreciate management’s reasons and respect client’s decision. 2. Should auditors take explicit measures to prevent their clients from discovering or becoming aware of the materiality thresholds used on individual audit engagements? Would it be feasible for auditors to conceal this information from their audit clients
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Case 10-5 Danle Corporation In November 2008‚ Danle Corporation，a public company engaging in the design‚ development‚ manufacture‚ and assembly of motors，was sued because of safety issue of parts it manufactured. Danle made no disclosure of the lawsuit in Form 10-K since it determined that the risk of potential loss was remote and no amount of potential damages could be reasonably estimated. In October 2009‚ Danle was served a second complaint for the same reason. Danle’s external counsel believed
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asked who we are‚ what we do‚ and how were so good at it‚ we thought it would be a great idea if this weeks article answered some of those questions extensively. Incentive Solutions CEO Steve Damerow sat down for an enlightening Q&A session. Who is Incentive Solutions? Technology making incentive rewards easy. Incentive Solutions is a 20-year-old‚ debt free‚ employee-managed incentive marketing agency that uses the cloud and Mobile Apps to manage and communicate sales incentives to in-house employees
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Phase I - Aircraft Solutions Table of Contents Contents Executive Summary The purpose of this paper is to evaluate the computer security for Aircraft Solutions. When discussing computer security‚ the three main areas aspects of any computer-related system are confidentiality‚ integrity‚ and availability. Confidentiality determines the security or privacy of the system. Integrity refers to only the authorized users making
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situation Isom or P&C is facing? Isom joined the board of CIGNA in March‚ 1993 as the president of the property and casualty division. Situation at that moment can be described as • CIGNA P&C had total 6500 employees operating through the United States‚ $4 billion of revenues and very poor results for past five years. • Division was plagued with serious weakness in management and poor supplier relationships. • It was experiencing severe financial stress‚ loosing almost $1billion between 1989 and 1993.
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Anna James Case Study: HealthSouth Corporation Scandal Week3 Forensic Accounting: Ethics and Legal Environment Professor Erskine Hawkins HealthSouth Corporation is a large‚ public healthcare company that operates 93 inpatient rehabilitation hospital‚ 49 outpatient rehabilitation satellites‚ six long-term acute care hospitals‚ and 25 home health agencies. According to the company websites‚ it is “one of the nation’s largest healthcare providers specializing in rehabilitation”.5 The company
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Executive Summary April 21st 2007 To The Board of Directors Quantum Corporation‚ CA‚ USA From Mike Wais Director‚ eSupplyChain Group Quantum Corporation‚ CA‚ USA SUB: Redesigning of Supply Chain initiatives taken by eSupplyChain Group to include eHITEX Quantum Corporation had formed the eSupplyChain Group in April 2000 with the aim of restructuring it’s‚ then inefficient‚ supply chain and take the advantage of new emerging e-technologies to improve efficiencies
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Marketing Problems CUTCO Corporation 1. Situation Analysis I.Industry In 2007 the direct selling industry had approximately $30.8 billion in sales. Direct sellers are almost entirely independent contractors. Virtually any product can be sold via direct selling. Internet Sales accounted for 11.4% of direct selling dollars in 2007‚ however most direct selling websites focus on company information and distributor contact information. II.Company CUTCO Corporation is a private company that
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Case Question: In light of the International Division that Tingzon inherited‚ where and how should Jollibee expand next? Assessment: Jollibee Foods Corporation recognizes that a reconfiguration of its international strategies will assist the company in embarking on a plethora of opportunities outside of its existing markets. New Guinea‚ Hong Kong‚ and the United States offer the chance for the company to grow its brand globally‚ but success is not guaranteed. Jollibee can capitalize on its
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