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    Pat 1 Synthesis of 4-aryl-6-indolylpyridine-2-carbonitriles and evaluation of their biological activity Synthesis of 6-indolyl-4-aryl-3-cyanopyridine-2-one (1a-e) Employing the MCRs approach and microwave irradiation‚ an equimolar amounts of aromatic aldehyde‚ 3-acetylindole‚ ethyl cyanoacetate were reacted with excess of ammonium acetate in one-pot‚ reaction‚ under the microwave irradiation‚ afforded a novel series of 4-aryl-6-indolyl-nicotinonitrile-2-one derivatives 1a-e. Ethylene glycol was

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    Markscheme Chem SL P3 02

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    INTERNATIONAL BACCALAURÉAT BACHILLERATO c BACCALAUREATE INTERNATIONAL INTERNACIONAL MARKSCHEME May 2002 CHEMISTRY Standard Level Paper 3 12 pages M02/420/S(3)M+ –5– Subject Details: M02/420/S(3)M+ Chemistry SL Paper 3 Markscheme General ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! Each marking point is usually shown on a separate line or lines. Alternative answers are separated by a slash (/) – this means that either answer is acceptable. Words underlined are essential for the mark. Material

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    COS-Acyl) CGKRG Case Study

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    Part 5: Synthesis‚ characterization and evaluation of COS-SMCC-(fatty acyl) CGKRK as in vitro gene delivery system to MDA-231 The delivery of siRNA is a great challenge due to its susceptibility to serum nuclease digestion‚ quick renal clearance. In addition to its anionic charge which hampers its cellular uptake. Therefore‚ the success of the gene carrier system relays on‚ the design of a delivery system that can protect siRNA molecules from enzymatic degradation‚ the ability to translocate the

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    containing the triphenylmethanol from the aqueous phase. The triphenlmethanol was then isolated and purified by crystallization and vacuum filtration. Reaction Scheme: Mechanism: The nucleophilic phenyl magnesium bromide attacks the electrophilic carbonyl of benzophenone to form a magnesium alkoxide. This is followed by hydrolysis by an acid to produce the alcohol‚ triphenylmethanol. Procedure: The procedure followed was as is described in "Laboratory Manual for Organic Chemistry 2311‚" Fifth

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    Chem Worksheet

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    Question 1 Consider the following equilibrium.4NH3(g) + 3O2(g) | View Full Image | | 2N2(g) + 6H2O(g)Suppose 0.30 mol of NH3 and 0.40 mol of oxygen are added to a 5.0-L container. If x mol of water is present at equilibrium‚ what is the equilibrium concentration of oxygen?Answer 0.40 - 0.50x | 0.30 - 0.50x | 0.08 - 0.10x | 0.06 - 0.13x | 0.40 - | View Full Image | | x | 4 points Question 2 At 298 K‚ the value of Kc for the reaction

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    Preface

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    fourth edition ORGANIC CHEMISTRY Francis A. Carey University of Virginia Burr Ridge‚ IL Dubuque‚ IA Madison‚ WI New York San Francisco St. Louis Bangkok Bogotá Caracas Lisbon London Madrid Mexico City Milan New Delhi Seoul Singapore Sydney Taipei Toronto | v v Boston | e-Text Main Menu | Textbook Table of Contents | Study Guide Table of Contents McGraw-Hill Higher Education A Division of The McGraw-Hill Companies ORGANIC CHEMISTRY‚ FOURTH EDITION

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    pyridine

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    Reactions of pyridine Introduction: 1. Pyridine structure: 2. Iupac name: Pyridine‚ other name: Azine & Azabenzene. *Important commercial alkyl pyridinium compound is α - methyl- pyridine (2)‚ βpicoline (3)‚ γ- picoline ( 4 ) ‚ 2‚6 - lutidine ( 5 ) ‚ 3‚5 - dimethyl- pyridine ( 6 ) ethyl-2 - methyl- pyridine ( 7 ) and 2‚4‚6 - collidine ( 8 ) . In general‚ the alkyl -substituted pyridine as many other precursors used in pyridine E-commerce. From these further alkyl substituted pyridine

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    Classification for Functional Groups Alcohols Lucas test (Differentiates primary‚ secondary‚ and tertiary alcohols) Reagent: ZnCl2 in conc. HCl Observation: Rate of reaction (tertiary alcohol> secondary alcohol> primary alcohol) Procedure: 2mL Lucas Reagent in test tube+ 3-4 drops of alcohol‚ stopper‚ shake vigorously‚ NOTE time required (less than 10m mins only) to form an emulsion or separate layers. Oxidation (Confirms if alcohol is oxidizable: presence of H in C-OH bond) Reagent:

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    Cell Biology Study Guide

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    Cell Biology (PCB 3023) Fall 2012 Review for Exam 1 Chapter 1 List the key commonalties and differences between prokaryotic and eukaryotic cells. Prokaryotic – no organelles; no nucleus; bacteria and Achaea; spherical‚ rodlike/corkscrew-shaped; cell wall; Eukaryotic – has nucleus; has organelles Commonalities – contain DNA that stores genetic information What is the main component of cellular membranes? What function(s) do membranes serve in cells? Made of phospholipids; defines

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    Work

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    Chapter 12 Gene Expression at the Molecular Level 1. Bread mold can grow in a minimal medium without supplements (wild type) while certain mutated strains (mutants) can only grow in a minimal medium that is supplemented with specific intermediates found in the following metabolic pathway for arginine synthesis: minimal ------> ornithine -------> citrulline ------> arginine‚ where enzyme 1 converts the precursor to ornithine‚ enzyme 2 converts ornithine to citrulline‚ and enzyme 3 converts citrulline

    Free DNA RNA Messenger RNA

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