Eli Lilly and Co. is a pharmaceutical company that was founded in 1876 by Colonel Eli Lilly.4 Its first major breakthrough was the development of gelatin coating for pills‚ which later turned into the gelatin capsules. Since 1876 Eli Lilly and Co. has been a pioneer in the pharmaceutical industry.5 The main focus of Lilly is the research and development of neuroscience and endocrinology drugs. They have expanded their operations over time into over 60 nations worldwide. The pharmaceutical sector
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osborne@ubc.ca www.sallyosborne.com Objectives 1. Specify in what forms O2 & CO2 are carried in the blood. 2. Describe the physiological significance of the oxyhemoglobin dissociation curve. 3. Relates shifts in the position of this curve to affinity of Hb & oxygen loading / unloading in the blood. 4. Describe the effect of anemia & carbon monoxide poisoning on tissue oxygenation. 5. Identify the color of hemoglobin in the following forms: 1) oxyhemoglobin‚ 2) deoxyhemoglobin 3) caboxyhemoglobin. 6. Specify
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STRATEGIC ALLIANCE ASSIGNMENT On Eli Lilly’s Strategic Alliance Management Function SUBMITTED TO: Prof: Muqbil Burhan SUBMITTED BY: Smiti Rastogi 063053 IMG-6 FORE SCHOOL OF MANAGEMENT INTRODUCTION Eli Lilly and Company has been in business for more than 135 years. The global‚ research-based company was founded in May 1876 by Colonel Eli Lilly in Indianapolis‚ Ind.‚ in the Midwestern section of the United States. He was a 38-year-old pharmaceutical chemist and a veteran
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dan elemen yang harus di kelola sehingga mampu mengambil keputusan terbaik dalam menghadapi persaingan global. Buku Wajib Hill‚ Charles W and Blake‚ Hughes M. International Business‚ Competing in the Global Maketplace‚ 6th ed‚ Mc Graw Hill 2007 (HB) Buku lain yang dijadikan referensi Griffin‚ Ricky W. and Pustay‚ Michael W. International Business‚ 5th ed‚ Prentice Hall 2007 (GP). Penilaian Ujian Tengah Semester 30% Ujian Akhir Semester 30% Tugas/Paper tengah semester pertama
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In the article by John Cloud‚ “The Myths of Bullying‚” he expresses the exaggeration of the supposed growing “epidemic” of bullying that is spreading across schools. He then begins by presenting two stories that relate to bullies and victims of bullying in their own right. One of which is about a shooting at Chardon High School‚ Ohio‚ where 5 students were shot and 3 killed. The other is about a suicide at Rutgers University where the victim was supposedly tormented by his roommate causing him to
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good Muslim. The five pillars are that there is no god but God‚ to offer prayer‚ to give charity‚ perform the hajj and to fast during Ramadan (HB 1: 7). The Muslims that follow the five pillars and follow Muhammad’s teachings will reach paradise. The first pillar is to accept that God is the only god and that he is the only one worthy of being worshiped (HB 1: 7‚ 25‚ 50‚ 63‚ 2: 594‚ Q 2: 176). This first pillar is very important in Islam because Islam is based around the idea of submitting to God
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Metallobiomolecules METALLOBIOMOLECULES CONTENTS 1. Introduction Metallobiomolecules 2. Classification Metallobiomolecules 2.1. Transport and of to Storage Proteins 2.2. Oxygen binding Today scientists try to explore the chemistry basis behind the biological processes. As a result of this‚ new areas have evolved such as bioinorganic chemistry and bioorganic chemistry. In this section we will talk about an important concept in bioinorganic chemistry called “Metallobiomolecules”. Metallobiomolecules
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dissolved O2 (1.5%) b. 98.5 % – bound to Hemoglobin (iron in Heme group) 2. Hemoglobin saturation a. 4 O2 = 100% b. 2 O2 = 50% c. Hb binds O2 reversibly B. Oxygen-Hemoglobin dissociation curve 1. Relates saturation of Hb with pO2 increase Hb saturation ( ↑ affinity)2. increase pO2 —— a. Hb stores O2 decrease Hb saturation (↓affinity)3. decrease pO2 —– a. Hb releases O2 4. Normal tissue 75% (pO2 = 40 mmHg)a. 97% (pO2 = 95 mmHg) —– b. Venous blood has large O2 reserve 5. Active tissue
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nitrogens from tetrapyrrole ring system ii. 5th bond - Helix F binds to Fe at terminal Histidine th * 5 bond = helix F8‚ residue 93 in Mb‚ molecule (His F8)* = proximal histidine residue 92 in the β-chain of Hb and iii. 6th bond – deoxygenated: empty‚ histidine residue from residue 87 in α-chain of Hb th helix E** hovers; oxygenated: oxygen bonds here ** 6 bond = helix E7‚ His 64 for Mb‚ His 63 in b-chain and 58 in a-chain c. Oxygen binds to Fe at 120° angle easily removed II. MYOGLOBIN A. Physico-chemical
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PACE UNIVERSITY Managing Innovation MBA-678 - Fall 2014 Section(s) CRN 71670 (lecture)‚ - Tuesdays 5:40-8:30PM Classroom(s): PNY W-522 Professor: John C. Byrne‚ Ph.D. Office: W491 (PNY). Pace Phone: 212-618-6581 Office Hours: Home Phone: 201-722-1459 – BEST ! Tue.: – 02:30-5:00pm – PNY e-mail: jbyrne@pace.edu – BEST ! Wed: – 02:30-5:00pm – GC Due to having to visit multiple campuses and the usual sundry meetings‚ etc.‚ it would be best to send me a note with a request
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