diagnosed with Aplastic Anemia‚ and a low chance of survival. It occurs when the bone marrow stops making a sufficient amount of healthy blood cells. As I went through the treatments I kept learning about the lab results and found out about the field of clinical laboratory science. I quickly became fascinated about the profession. The more I learned about it‚ the more I felt drawn to pursuing a career in clinical laboratory science. It took two years to get my aplastic anemia under control‚ and soon
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Genetics of Sickle Cell Anemia Objectives • To observe how a disease can act as a selective force • To describe changes in allele frequencies in a population as a result of a selective force Hypothesis The starting ratio of HbA to HbS is 3:1; in a typical population‚ the Homozygous Dominant Gene would become the standard‚ but because carrying the Heterozygous version of the allele has an advantage to fighting Malaria it will become the dominant Allele for the population. The HbA/HbS gene will
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Evolution of Disease Sickle Cell Anemia Sickle Cell Anemia is a disease that which the red blood cells form an abnormal sickle or crescents shape. Red blood cells are very important to the human body because they carry oxygen throughout the body. The main causes of Sickle cell is when the cells in the body mutate into abnormal cell called haemoglobin S. Haemoglobin S causes the red blood cells to become sickle shaped‚ rigid. This causes to make it more difficult for the cells to flow the vein
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Sickle cell anemia was first discovered in the year of 1910. A young man by the name Walter Clement Noel from the island of Grenada‚ studied in Chicago. He went to Dr. James B. Herrick‚ whom was a cardiologist‚ with symptoms of anemia‚ who assigned Dr. Ernest Irons to the case. There Dr. Irons noticed that Noel’s red blood cells were the shape of a sickle. Although sickle cell anemia has occurred in Africa for thousands of years‚ Dr. Herrick was the first to provide a formal description of sickle
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In this paper‚ the reader will learn about Sickle Cell Anemia. The reader will learn what Sickle Cell Anemia is. The diagnosis of Sickle Cell Anemia will be discussed‚ along with the signs‚ symptoms and treatment for Sickle Cell Anemia. Sickle Cell Anemia is a genetic disorder dealing with the red blood cells within the body. The abnormality deals with the formation of hemoglobin within the blood cells. The hemoglobin abnormality is called hemoglobin S. The Sickle Cell gene need to be inhered from
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Introduction Pernicious anemia (PA) is a type of macrocytic normochromic anemia. It is a slow-developing disorder with the underlying cause of Vitamin B12 absorption and deficiency due to lack of intrinsic factor (IF). Vitamin B12 absorption is facilitated by IF‚ which binds B12 in the duodenum‚ forming the IF-vitamin-B12 complex‚ later recognized by receptors and absorbed in the jejunum (Anderson‚ et al.‚ 445). A consequence of vitamin B-12 deficiency is altered DNA replication and erythropoiesis
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Anemia is a condition in which there is lower than normal number of red blood cells or hemoglobin within a person‚ consequently decreasing the amount of oxygen being carried to the rest of the body. Causes of such a condition are usually insufficient amounts of iron‚ blood loss‚ lack of red blood cell production‚ or high rates of red blood cell destruction. (MNT‚ http://www.medicalnewstoday.com/articles/158800.php) One form of this condition is the disease Sickle Cell Anemia‚ an inherited blood disorder
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Sickle cell anemia (SCA) is a genetic disorder that is hereditary. It affects the blood‚ and is caused when the hemoglobin in blood cells are deprived in oxygen from the proteins. These cause normal round blood cells‚ to have are rigid sickle shape. People affected by SCA have a higher risk of death‚ stroke‚ severe attacks‚ and severe rushes of pain. James Herrick discovered an anemia‚ and found bizarre sickle-shaped cells in 1910. A treatment for the disease was discovered in the 1920s by E. Vernon
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Anemia is not a disease‚ but a sign that the body has some sort of problem with its red blood cells (RBCs). If a person’s blood does not have the right amount of red blood cells or hemoglobin‚ anemia can develop. Anemia is defined as a decrease in the circulating red blood cell mass and an equal decrease in the oxygen carrying capacity of the blood (also known as hemoglobin). There are many types of anemia that are grouped by their underlying cause. To determine which type‚ doctors describe color
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SICKLE CELL ANAEMIA Sickle cell anemia is an inherited condition. People with sickle cell anemia inherit two copies of the sickle cell gene‚ one from each parent. The sickle cell gene makes abnormal hemoglobin called Hemoglobin-S. The sickle cell gene is a trait due to a change in ONE nucleotide in the DNA sequence that leads to a change in ONE amino acid that changes how the hemoglobin protein folds. This change in the structure of the hemoglobin protein leads to a change in the shape of
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