HUMAN GENE THERAPY 22:1–10 (August 2011) ª Mary Ann Liebert‚ Inc. DOI: 10.1089/hum.2011.087 Review Zinc-Finger Nucleases for Somatic Gene Therapy: The Next Frontier 1 Shamim H. Rahman‚ Morgan L. Maeder‚2‚3 J. Keith Joung‚2‚3‚4 and Toni Cathomen1 Abstract Zinc-finger nucleases (ZFNs) are a powerful tool that can be used to edit the human genome ad libitum. The technology has experienced remarkable development in the last few years with regard to both the target site specificity and the
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INDIAN ACADEMY OF SCIENCES YEAR BOOK 2013 Postal Address Indian Academy of Sciences C.V. Raman Avenue Post Box No. 8005 Sadashivanagar Post Bangalore 560 080 India Telephone Fax Email Website : : : : (080) 2266 1200‚ 2266 1203 (080) 2361 6094 office@ias.ernet.in‚ execsec@ias.ernet.in www.ias.ac.in Text formatted by Wintecs Typesetters‚ Bangalore (Ph. 2332 7311). Printed by Brilliant Printers Pvt Ltd.‚ Bangalore (Ph. 2341 2455). CONTENTS Page Memorandum of Association . . . . . . . . . . .
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CARDIAC TUMORS INTRODUCTION Cardiac tumours occur quite rarely‚ with metastatic neoplasms three times more prevalent than primary tumours. A large variety of benign and malignant tumours of the heart have been described. These tumors are found mainly in the heart‚ but can occur in the pericardium or the great arteries. Secondary cardiac involvement from malignant tumors of adjacent organs (lung‚ thymus) or from kidney (Wilms tumor) or liver‚ or even remote organs‚ are also seen. ANATOMY AND PHYSIOLOGY
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1. Introduction Toxicology is defined as "the study of the adverse effects of chemical‚ physical or biological agents on living organisms and the ecosystem" and is based on the 16th century principle that any substance can be toxic if consumed in sufficient quantity. In a general sense‚ the toxicity of a substance could be defined as the capacity to cause injury to a living organism. [1] A highly toxic substance will damage an organism if administered in very small amounts; a substance of low toxicity
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Induced pluripotent stem cells from human revertant keratinocytes for the treatment of epidermolysis bullosa Noriko Umegaki-Arao et al. Sci Transl Med 6‚ 264ra164 (2014); DOI: 10.1126/scitranslmed.3009342 Editor ’s Summary Epidermolysis bullosa (EB) is a rare‚ inherited skin disorder that causes such severe blistering that patients are often relegated to a delicate life in bandages. Like a patchwork quilt‚ the skin of a patient with EB can consist of both mutated skin cells (which cause the disease)
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Are You a Good or Bad Student? Being a good student is what everyone wants to believe they are. But in reality we all know that there are bad students. I‚ myself would like to believe I am a good student but when I looked over the facts it seems that I am not a bad or a good student. The first and foremost important quality of a good student is‚ of course‚ hard working. We can’t have a good result in academic success without training and effort. The next quality is active in community. A good student
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Developmental Biology 278 (2005) 274 – 288 www.elsevier.com/locate/ydbio Review Friedrich Miescher and the discovery of DNA Ralf Dahm* Max Planck Institute for Developmental Biology‚ Department 3 – Genetics‚ Spemannstr. 35/III‚ D-72076 Tubingen‚ Germany ¨ Received for publication 5 October 2004‚ revised 17 November 2004‚ accepted 20 November 2004 Available online 21 December 2004 Abstract Over the past 60 years‚ DNA has risen from being an obscure molecule with presumed accessory or structural
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Team Anthro Anthropology Notes Paper I Arava‚ Uday Table of Contents CSE Anthropology Syllabus 5 Paper - I 5 Notes 9 1 Meaning‚Scope and Development of Anthropology 9 2 Relationship with other disciplines 10 2.1 Anthropology(A) and social science 10 2.2 Anthropology and behavioral science 10 3 Main Branches of Anthropology: 11 3.1 Social cultural anthropology 11 3.2 Biological Anthropology 12 3.3 Archaeological anthropology - 13 3.4 Lingusitic Anthropology 14 4 Biological Factors in Human
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UNIVERSITY OF IBADAN POSTGRADUATE SCHOOL GUIDE TO ADMISSIONS 2012/2013 1 When the roll is called of those who deserve resounding success by their hardwork and devotion You surely will answer ‘aye’! But the race is not always won by the best horses Accidents do occur‚ It is the wish of the Postgraduate School that the efforts of most of you be crowned with resounding success in the quest for truth and knowledge in the Nation’s Premier Institution of Higher Learning. • LINKS E-mail:
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INTRODUCTION: Women who constitute half a human population have been discriminated‚ harassed and exploited irrespective of the country to which they belong‚ unmindful of the religion which they profess and oblivious of the timeframe in which they live. Everywhere women are confronted with many challenges. Female foeticide is perhaps one of the worst forms of violence against women where a woman is denied her most basic and fundamental right i.e “the right to life”. The phenomenon of female foeticide
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