Acetaminophen Abstract: The aim of this experiment is to prepare Acetaminophen (p-acetamidophenol)‚ an amide. Acetaminophen will be created by treating an amine (p-aminophenol) with an acetic anhydride. Color impurities present in the solid acetaminophen will be removed and then the decolorized product will be collected on a Büchner funnel for further purification by crystallization. Purity will then be determined by melting point. Introduction: Acetaminophen is commonly used as an analgesic to
Premium Melting point Yield Acetic anhydride
Chemistry Synthesis of ACETAMINOPHEN Laboratory Report 1 CHEM 123L January 19‚ 2014 Prepared for: Dr. S. Stathopulos Department of Sciences‚ Chemistry Faculty University of Waterloo Teaching Assistant: Aaron Chan Prepared by: Section 001 Vithurjan Satkunarasan 20495383 Lab Partner: Ken Xu Introduction The synthesis of Acetaminophen is based on the amine group of p-aminophenol being acetylated by acetic anhydride to form an amide functional group. Acetaminophen is isolated as a crude solid
Free Melting point Chemistry Solid
Experiment 1 Synthesis of Acetaminophen Clifford Tse 20529845 Partner – Raminder Dhanoa TA – Xiao Qi CHEM 123L - 012 February 6‚ 2014 Introduction Acetaminophen‚ also commonly known as Tylenol‚ is an over-the-counter medicine used to relieve pain and reduce fevers. Within this experiment‚ Acetaminophen will be formed through the reaction between p-aminophenol and acetic anhydride. This reaction will incur Acetaminophen as a crude solid being impure‚ which will be purified further through
Premium Aspirin Acetic acid Carboxylic acid
Introduction: Acetaminophen is a commonly used analgesic‚ which is essentially just a medicine that relieves pain (Prescott‚ 2000). Acetaminophen is created by synthesizing p-Aminophenol with Acetic anhydride. This reaction occurs when the amine group of the p-aminophenol is acetylated by the acetic anhydride. The resultant is an amide functional group (Ellis‚ 2002). However‚ the product that is obtained from this product is a crude solid which cannot be used as an analgesic and therefore the crude
Free Aspirin Carboxylic acid Acetic acid
Some consumers want to know if acetaminophen dissolves faster in the form of tablets‚ gelcaps‚ or caplets in order to get the fastest pain relief. The purpose of this experiment was to find out which of the three tested forms of acetaminophen would dissolve the most over a time period ten minutes. The hypothesis stated that the tablets would dissolve the most over the ten minutes. The hypothesis was tested by dropping ten of each of the forms of the acetaminophen into two thirds a cup of boiling
Premium Solution Solubility Chemistry
Small samples of acetaminophen‚ acetylsalicylic acid‚ cellulose‚ starch‚ and caffeine were obtained. These samples were then placed into seperate sets of test tubes that contained water‚ acetone‚ or dichloroethane. Solubilities were then tested for each sample in each solution which can be seen in Table 5. Next‚ four random pills were obtained and weights were taken of each. Each of the pills were grinded up using a separate mortar and pestle. The grinded up pills were then weighed. The grinded
Premium Chemistry Water Oxygen
Drug Store Items Knowns Rf Values Aspirin .91 cm Acetaminophen .85 cm Ascorbic Acid .86 cm Unknown .97 cm Identity of unknown mixture Acetaminophen Analysis of Paprika Pigments Spot Number Rf Color 1 1 Red-orange 2 1 Red-orange Calculations A. Analysis of Paprika picture sample B. Flower sample for paper chromatography Analysis of Drug Store Items Knowns Rf Values= a/f Aspirin 7.0/7.7= .91 cm Acetaminophen 7.7/7.7= 1 cm Ascorbic Acid 6.6/7.7= .86 cm Unknown
Premium Aspirin Salicylic acid Acetic acid
Reformist Clinton: Pioneering Women’s Rights Revolution In September 1995‚ then-First Lady of the United States‚ Hillary Clinton delivered a riveting speech on Women’s Rights before the Fourth World Conference on Women in Beijing. She hosted delegates around the world‚ creating a Platform of Action to achieve greater equality and opportunity for women. This immensely assertive speech stood out amongst others in that period as it was hosted by a prominent female leader in the ‘capital of a brutal
Premium Hillary Rodham Clinton Women's suffrage Women's rights
Experiment 3: The preparation of acetaminophen (paracetamol) with thin layer chromatography (TLC) to monitor the reaction. Abstract: This experiment is to demonstrate the preparation of paracetamol and its properties. Reflux and filtration of 4-aminophenol and acetic anhydride formed the crude sample. Further analysis of dry white crystals were used to give quantitative measurements and a percentage yield of 46% was obtained. The overall conclusion is that the acetic anhydride reacted with the
Premium Functional group Thin layer chromatography Acetic acid
vial attached to an air condenser to synthesize crude acetaminophen‚ resulting in 0.097 grams (47.48% yield). The crude acetaminophen was then recrystallized in a solvent of water and methanol over heat resulting in 0.082 grams (39.61% yield) of pure acetaminophen. Melting points of both crude and pure acetaminophen were taken‚ and found to be 165.9 - 170.9°C and 168.2 - 171.5°C‚ respectively. The literature melting point of acetaminophen is 169.5 – 171.0°C‚ indicating that our final product was
Premium Stoichiometry Paracetamol Acetic anhydride