Critique of Systematic Review of intravenous acetaminophen Chamberlain College of Nursing NR505: Advance Research Methods: Evidence-Based Practice Fall Session A‚ 2013 Abstract According to the systematic review covered by Apfel‚ Turan‚ Souza‚ Pergolizzi & Hornuss‚ 2013 there is a significant reduction in postoperative nausea and vomiting and opioid use when using intravenous acetaminophen. The reviewers used Medline and Cochrane databases to conduct their search along with a hand search of
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Title: Separation and Identification of the major components of common over-the-counter painkilling drugs Purpose: 1.To separate acetaminophen‚ aspirin and caffeine from painkilling drugs. 2.To determine the melting points of acetaminophen‚ aspirin and caffeine 3.To identify the separated components(acetaminophen‚ aspirin and caffeine) by thin-layer chromatography Apparatus and Reagents Used : 1. 4:1 (v/v) 1-Butyl ethanoate/ethanoic acid 2. 3M Sodium hydroxide solution 3. 3M Hydrochloric
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procedure stated in Chem 2120 experiment 6 Williamson Ether Synthesis of Phenacetin laboratory manual was followed without any major changes. Data and results Compound Amount used MW (g/mol) Moles Stoichiometry/Comments acetaminophen 0.354 g 151.16 2.34 x 10-3 limiting reagent ethyl iodide 0.3mL 155.97 3.75 x 10-3 1.6 equiv ’s sodium ethoxide 2.6mL 68.05 3.3 x 10-2 catalyst‚ reaction solvent crude product obtained: phenacetin 0.32g 179.22 1.78 x 10-3
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Analgesics Using the thin layer chromatography the major components of a commercial analgesic tablet will be indentified and purified. The active ingredients of the analgesic used were characterized by comparison with chromatograms of aspirin‚ acetaminophen‚ ibuprofen‚ mefanemic acid‚ and caffeine through the use of UV chromatography then the Rf value was calculated for each solvent. INTRODUCTION In this experiment‚ thin-layer chromatography (TLC) will be used to determine the composition
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name of a pain medication. 2. Vicodin was originally approved by the FDA in January 1983 3. It is used by people who live with arthritis or other chronic pain conditions. 4. Each Vicodin tablet contains 5 mg hydrocodone bitartrate and 500 mg acetaminophen. II. PREVIEW/ ORIENTAL MATERIAL 1. I will be making an analysis on the use of Vicodin how positive and negative it has affected people as a pain killer medication. 2. The concept of this speech will be on the content of each Vicodin tablet‚
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prepared by reacting salicylic acid with acetic anhydride:  Figure 1. Chemical Equation for Aspirin Synthesis (Aspirin) Tylenol‚ acetaminophen‚ is also used both as a fever reducer and pain reliever. Acetaminophen is prepared by reacting ammonia with acetic acid:  Figure 2. Chemical Equation for Tylenol Synthesis (Acetaminophen) The purity of an aspirin or Tylenol sample can be obtained by determining the melting point. The presence of impurities always lowers the melting
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over-the-counter classifications of painkillers are acetaminophen‚ nonsteroidal anti-inflammatory drugs (NSAIDs)‚ and salicylates. One of the most popular over-the-counter drugs used to relieve pain is Tylenol. Tylenol is the brand name for acetaminophen or paracetamol. Consumers take acetaminophen to relieve mild to moderate pain such as for osteoarthritis or headaches. The National Center for Biotechnology Information (NCBI) says that acetaminophen works by changing the way the body senses pain (2012)
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------------------------------------------------- Drug Name: Hydrocodone/Acetaminophen Trade Name: Vicodin ------------------------------------------------- Indication: Relief of moderate to severe pain ------------------------------------------------- Safe Range: Peds: <40kg 0.2mg/kg-15mg/kg/dose q3-4h PRN. Maximum dose of acetaminophen 1000 mg/dose and 4000mg/day; Adult initially 10mg q3-4h PRN. ------------------------------------------------- Action / Where does it
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in 24 hours” and “adults and children 12 years of age and over: 2 caplets every 6 hours while symptoms persist”. (Benadryl) So what happened in this case? Acetaminophen is an active ingredient in Benadryl® Maximum Strength Severe Allergy and Sinus along with Diphenhydramine and Pseudoephedrine. In each capsule‚ there is 500 mg of acetaminophen‚ therefore the is 1000 mg in one dose‚ and 4000 mg
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where the given distance from origin to solvent front measures 59 mm: 1.) acetaminophen has a Rf value of 0.48; 2.) aspirin has a Rf value of 0.64; 3.) caffeine has a Rf value of 0.22; 4.) Biogesic® sample has a Rf value of 0.48 ; 5.) ibuprofen has a Rf value of 0.73; and 6.) mefenamic Acid has a Rf value of 0.76. Thus‚ the study shows that by having equal Rf values of about 0.48‚ Biogesic®’s most active component is acetaminophen (paracetamol)‚ a relatively polar compound having a molecular formula
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