SICKLE CELL ANEMIA Dillon Lukacs Normal Circulatory system In a normal circulatory system blood flows easily through the veins and arteries. Oxygen is delivered throughout the body to all the vital organs. Sickle Cell Disease An anemia is a condition where there are less red blood cells than normal. Sickle cell anemia is a disorder where the body creates sickle or crescent shaped red blood cells. In a normal blood cell they look like donuts with a hole in the middle. This shape helps them
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tests done on the genetic causes of Sickle Cell Anemia and how it developes‚ as well as it’s effects on the circulatory‚ muscular‚ and respiratory systems‚ as well as it’s effects on the joints and other systems of the body‚ and the complications associated with them. Most of the research has been done to explore on the reasons why it mostly effects the African-American community and people who are from the West Coast of Africa. It has also been known that Sickle Cell Anemia also effects people from
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09/08/2012 Sickle Cell Disease Blood has been considered the essence of life for centuries‚ and our blood is a living tissue made up of liquid and solids. There are many diseases related to blood such as anemia which is the decrease in oxygen supply to tissue and causes hypoxia‚ thalassemia is the mutation in one or more globin gene of hemoglobin‚ etc. Therefore‚ one of blood disorders is the most common symptomatic hemoglobinopathy with the greatest prevalence in worldwide which is called sickle cell
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Sickle Cell Anemia Pathophysiology: Sickle cell anemia is a disease passed down through families in which red blood cells form an abnormal crescent shape. The “sickling” occurs because of a mutation in the hemoglobin gene. Sickle cells are stiff and sticky. They tend to block blood flow in the blood vessels of the limbs and organs. Blocked blood flow can cause pain‚ serious infections‚ and organ damage. Life expectancy in people who have this disease is shortened. Anemia is a condition in
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Abstract Sickle-cell disease is a genetic disorder that results from the abnormal structure of red blood cells. The peculiar shape of the red blood cell prevents the normal absorption of oxygen. This disease results from the abnormal production of hemoglobin S (HbS). Therefore‚ a mutation in this gene causes a lower supply of oxygen to the cells‚ which results in occlusion of the blood vessels. Individuals diagnosed with sickle-cell anemia have abnormal function of the gene that encodes for subunit
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SICKLE CELL ANEMIA Tina Thompson‚ Ashley Scott‚ Araceli Galindo‚ Roshanda Dixon‚ Kristen Wyatt‚ Kimberly Dennis What is Sickle Cell Anemia? Sickle cell anemia is a severe hemolytic anemia resulting in a sickle shaped hemoglobin molecule. It is an inherited disorder with some having sickle cell trait and some having sickle cell disease. The sickle hemoglobin gene is known as the HbS gene. It is found predominantly in people of African descent and occasionally in those of Mediterranean descent
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‘How could natural selection increase the number of children born with sickle-cell disease in certain regions when these individuals are unlikely to survive and produce offspring?’ Darwin’s theory proposes that 3 conditions are a requisite for natural selection to occur. They are a struggle for existence of the offspring as they are competing for limited resources‚ variation within species which gives some individuals advantage over others hence better chance of survival and lastly inheritance
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Sickle Cell Anemia Sickle cell anemia is an inherited blood disease. The word anemia is defined as meaning that the blood does not have the required number of red blood cells. These cells take on a crescent shape‚ which is where the disease takes its name from the abnormal sickle shapes of the cells. It is commonly found in people from Africa‚ the Mediterranean region‚ southern India and the Middle East. “This disease of the blood was first discovered in 1910 in a black college student from the
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To understand the complexities of Sickle cell anaemia and Sickle cell disease a basic understanding of haemoglobin is essential. (See appendix 2) Appendix 3 shows a normal red blood cell and a sickled red blood cell‚ you can see the difference is more than noticeable. This essay will look at three themes and look at areas of research found by the author‚ an analysis and evaluation of the research found will be given. A conclusion will then be given of the information found during the research process
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is lowered‚ these cells change their forms from the normal biconcave disk to crescent‚ holly wreath‚ and other forms. This process is known as sickling. What is Sickle Cell Anemia? It is a blood disorder that affects hemoglobin‚ red blood cells with normal hemoglobin move easily through the bloodstream‚ delivering oxygen to all of the cells of the body. Normal red blood cells are shaped like doughnuts with the centers partially scooped out and are soft and flexible. Sickle cell anemia occurs when
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