Sickle cell anemia is a genetic disease that affects the shape and functionality of red blood cells. It is caused by a mutation in the DNA of the protein‚ hemoglobin‚ specifically in the beta chain. There are 531 base pairs in this DNA strand. Substitution or point mutation occurs‚ causing “GAG” to become “GTG”. This results in valine being created instead of glutamate. The mutation causes the hemoglobin to cling together in low oxygen levels and the red blood cell changes shape‚ preventing it from
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Stem Cells: Are They the Cure for Diabetes? Stem Cells: Are They the Cure for Diabetes? Diabetes is a disease that affects 25.8 million people in the United States alone‚ not to mention the 7.0 million people who are undiagnosed and the staggering 79 million people who are pre-diabetic (Centers for Disease Control and Prevention‚ 2011). That number alone should send out an alarm that a cure is needed. Not just a treatment‚ but a real cure that will free sufferers from the strict
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Describe the cell cycle. Include in your discussion the role cyclins and CDKs play in controlling this cycle. The cell cycle is a process that cells undergo to grow‚ reproduce‚ and divide to make 2 daughter cells. The cell cycle has different stages including G1‚ S‚ G2‚ and the M phase. Also we have the G0 phase. There are checkpoints that control the transitions between the phases of the cell cycle in which the process is regulated by cyclins and cyclin-dependent kinases (CDKs). G1 is known as
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Sickle Cell Disease (Anemia) Child and Adolescent Development (PSC 1246A) Sickle Cell Disease‚ commonly referred to as Sickle Cell Anemia‚ is a blood disease which red blood cells form an abnormal sickle or crescent shape. Red blood cells carry oxygen to the body and are normally shaped like a disc. This disease is genetically inherited from both parents. If you inherit the sickle cell gene from only one parent‚ you will have sickle cell trait. People with sickle cell trait
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Critical Care Nursing: Sickle Cell Anemia Critical Care Nursing 10/15/2009 Sickle cell anemia affects millions of people worldwide. Sickle cell anemia is a disease in which your body produces abnormally shaped red blood cells. They don’t last as long as normal‚ round red blood cells‚ which leads to anemia. Sickle cells contain abnormal hemoglobin that causes the cells to have a sickle shape. Sickle-shaped cells don’t move easily through your blood vessels. They’re
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Mr. Evje 3/10/13 ASTHMA Asthma is a lung disease that is chronic and it aggravates and tightens the airways of a person. Asthma cause recurring periods of wheezing‚ which is a whistling sound when a person breathes‚ tightness in the chest area‚ a shortness of breath‚ and coughing. Coughing mostly happens at night time or either early in the morning. The airways are the tubes that carries air in and out of the lungs‚ so it is difficult for a person who has asthma because their airways are
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Differential diagnose 1: Sickle Cell Anemia A 17-year-old African American female presented to the clinic with the following symptoms‚ chest and abdominal pain‚ and jaundice eyes. Her vital signs revealed B/P 98/50‚ pulse 112‚ respiration. 28 and temp. 99.9. EKG and chest x-ray completed with the result within normal range. She was discharged‚ and within four hours returned to the ER. Sickle cell disease is defined as a group of heredity disorder characterized by abnormal hemoglobin‚ called hemoglobin
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Conclusion 1 Based on what you know about blood‚ why would having a sickle cell anemia crisis result in a reduced red blood cell count‚ an elevated white blood cell count‚ and a reduced hematocrit? There’s a reduced RBC count‚ elevated WBC count‚ and a reduced hematocrit because of the shape of the RBC. The sickle cell anemia causes the RBC to have a different shape; a crescent and rigid shape and there are not a lot of them. So because of that‚ there’s more WBC and a reduced hematocrit. Also‚ the
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offspring. He also discovered that traits pass down through families in different patterns. Sickle cell‚ which is an inherited disease‚ is mainly found in those of African descent. Mendel’s research ultimately helped lead to the discovery and understanding of the HBS allele‚ the connection of malaria to sickle cell now and in future generations‚ and the new technology that helps diagnose and treat sickle cell. In 1910‚ a black man named Walter Clement Noel‚ went to Dr. James B. Herrick‚ complaining
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Medical Issues- Stem Cells Click on The Nature of Stem Cells to answer the following questions. 1.) Compare a stem cell and a specialized cell. Specialized cells carry out specific functions. These specialized cells are called differentiated cells. On the other hand‚ a stem cell is undifferentiated. Its role in the body is not yet determined. A stem cell can give rise to multiple cell types‚ including many stem cells. 2.) Describe a blastocyst. The blastocyst looks like a lopsided hollow ball
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