1. What are the etiology‚ signs‚ and symptoms of malignant hyperthermia? Malignant hyperthermia is a disease that causes a rapid increase in body temperature and severe muscle contractions when someone with the disease receives general anesthesia. Most of the cases‚ there are no signs or symptoms of the condition until you are exposed to the medication. It is a hypermetabolism syndrome that affects the skeletal muscle due to the ryanodine receptor in skeletal muscle is abnormal and this interferes
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One‚ two‚ I remember counting my grandfather’s blood pressure pills every evening. At the same time‚ I would take a syringe‚ and place the correct amount of insulin in it for my grandmother. Since I was twelve years old‚ medicine has always been personal. Both of my grandparents were from Libya‚ spoke no word of English‚ and were illiterate. This combination made it very difficult for them to manage their own care. I would always accompany them to their medical appointments‚ and served as the intermediary
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Insulin plays a critical role in integration and regulation of carbohydrates and lipid metabolism. Insulin and regulation of carbohydrate metabolism Insulin is a peptide hormone which is secreted by the pancreatic beta-cell that present in the islet of Langerhans. It is a protein that function to regulate the metabolism of carbohydrates‚ fats and protein and also utilize of energy from the ingested nutrients especially glucose. Foods that consist of carbohydrates are converted into glucose during
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Acute Coronary Syndrome (ACS) is a medical condition that encompasses various heart-related ailments such as acute myocardial ischemia‚ unstable angina‚ non-ST-segment elevation myocardial infarction (NSTEMI)‚ and ST-segment elevation myocardial infarction (STEMI) (Kumar & Cannon 2009). NSTEMI and STEMI begins with atherosclerosis which happens when a plaque known as atherosclerotic plaque is formed from years of cholesterol deposits within the artery wall. When this ruptures the platelets clump
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CF is an autosomal recessive disorder caused by a mutation of the gene that encodes for a chloride channel called the cystic fibrosis transmembrane conductance regulator (CFTR). In ductal epithelial cells‚ CFTR is highly expressed and functions to transport fluid and anions into the lumen. Dysfunction of the CFTR gene leads to a decrease in luminal fluid volume and decreased pH‚ resulting in protein precipitation within the ductal lumen and loss of normal acinar cell function. Estimated gene frequency
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It’s more than chocolate ice cream and Oreos that hold a person together. Thus‚ connective tissues that function to support the body are necessary. Marfan syndrome is an inheritable‚ autosomal disease of the connective tissues resulting from a lack of the fibrillin-1 glycoprotein (Brown). The missense mutation on the FBN1 gene producing the fibrillin-1 protein decreases the amount produced available for function with other proteins (Defective Secretion)‚ facilitating deficient connective tissue formation
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Ghrelin is a fast-acting‚ 28 amino acid peptide hormone discovered in 1999. it’s structurally resembles motilin‚ they both share about 21% amino acid identity & their receptors also share structural similarity with 44% similarity in amino acids which indicates they belong to the same family. Ghrelin’s also able to cross the blood brain barrier which gives exogenously administered ghrelin a unique clinical potential. Ghrelin cells are ovoid with granules which are found primarily in the stomach &
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The endocrine system is one of our body systems that plays an important role in living. It comprises of many glands exerting hormones in maintaining the body’s internal environment also known as homeostasis. The endocrine system plays an important role in homeostasis because it maintains growth and development‚ maturation‚ reproduction‚ human behavior‚ metabolism‚ sexual function and controls functions of the tissues. It is partnered with the nervous system since the hypothalamus along with the pineal
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since 1982. Global warnings over diabetes increase. Research carried out by the International Diabetes Federation (2009) reveals that around 314 million people‚ equating to 8.2% of the global adult population‚ may have impaired glucose tolerance (IGT) which is a condition that often precedes the development of diabetes. The incidence of diabetes in Malaysia is similar to other countries in the world (Malaysian Diabetes Association‚ 2009). Diabetes Mellitus is one of the commonest chronic
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Diabetes Mellitus The main function of insulin is to maintain blood glucose homeostasis‚ Insulin also controls the transport of glucose from the bloodstream into the muscle and fat cells. The effect that insulin has on cells is that when blood glucose rises the pancreas respond by secreting into the bloodstream thus Insulin moves glucose from the blood into the cells. When insulin is not there or it doesn’t work blood glucose regulation fails and blood glucose levels rise so this shows that blood
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