1. A physician forgets to tell a patient about the risk of combining a prescribed drug with aspirin and the patient takes two aspirin for a headache: In this scenario the extend of liability depends on the drug being prescribed‚ if the drug is dispensing in generic form with no warnings‚ then the physician could be considered liable‚ however it is still possible to make the argument that the patient would have been proactive about potential contraindications‚ and consult the dispensing pharmacy
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I. INTRODUCTION Synthesis Acetylsalicylic acid is an acetyl derivative of salicylic acid which appears as a white and crystalline and a weakly acidic substance with a melting point of 135°C and is also known to be aspirin. It is one of the most widely used drugs that can lower fever and is used as a painkiller. According to (Escobel‚ 2011)‚ Aspirin is synthesized through the reaction of salicylic acid with acetyl anhydride that causes a chemical reaction that turns salicylic acid’s hydroxyl group
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and Recrystallization of Aspirin Preparation and Recrystallization of Aspirin Date of the experiment: 9 May 2013 Date of submission: 23 May 2012 Date of the experiment: 9 May 2013 Date of submission: 23 May 2012 Synopsis 1. General Objective: To familiarize with the preparation of some simple organic compound and purify the compound by recrystallization. Specific Objective: The experiment is carried out to: 1.1 Conduct the synthesis of aspirin 1.2 Reinforce the
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Aspirin Aspirin is a salicylate‚ also known as a non steroidal anti-inflammatory drug (NSAID). It is the generic name of acetylsalicylic acid and is used clinically to treat fever‚ pain and inflammation as it works by preventing the formation of prostaglandin. Prostaglandin is the active agent that is responsible for the sensitisation at the nerve endings. It can be administered orally‚ rectally or by intravenous route. (6) Benzene ring Carboxylic acid Ester Alkane Aspirin has a pKa of 3.49
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Today‚ aspirin is one of the most widely used medication on this Earth and has been since its popular breakout in the late 1890s. Long before we were born there was no such thing of a medication called aspirin. Instead‚ ancient people used willow leaves and bark from trees to help relieve oneself from pain and fevers. Aspirin as we come to know it in the form of an acetylsalicylic acid‚ was introduced to the world by Chemist Felix Hoffmann who was working at Bayer pharmaceutical company located in
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October 17 & October 24‚ 2012 How is Aspirin Made? This lab is about synthesizing aspirin using a hotplate to heat the reaction. It involved vacuum filtration‚ recrystallization‚ and comparing the properties of aspirin with salicylic aspirin. The first thing we did in this lab was make a hot-water bath by putting a beaker with water on a hot plate. After measuring out 2.1 grams of salicylic acid and 3 ml of acetic anhydride‚ we mixed the two together‚ along with 3 drops of sulfuric acid. We
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Darnell Shaw Lab Extra Credit Hippocrates of Cas (460-377 B.C.)‚ The Healer‚ noted that chewing leaves of willow (Salix) reduced pain‚ and he prescribed this remedy for women in labor. The Healer certainly did not discover this drug‚ which was used for centuries earlier in European folk medicine. Ancient Egyptians took an infusion of dried myrtle leaves to treat muscle pain. The myrtle leaves were also found to contain salicylic acid. Two Italians‚ Brugnatelli and Fontana‚ had in fact already
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EUROPEAN PHARMACOPOEIA 5.0 Acetylsalicylic acid TESTS Appearance of solution. Dissolve 1.0 g in 9 ml of alcohol R. The solution is clear (2.2.1) and colourless (2.2.2‚ Method II). Related substances. Examine by liquid chromatography (2.2.29). Prepare the solutions immediately before use. Test solution. Dissolve 0.10 g of the substance to be examined in acetonitrile for chromatography R and dilute to 10.0 ml with the same solvent. C. N‚N′-diacetyl-L-cystine‚ Reference solution (a).
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Commercial Aspirin Tablet Analysis Tuesday Evening Intro: The purpose of this lab was to analyze commercial aspirin tablets. To do so‚ the percent acetylsalicyclic acid (active ingredient) in tablets using acid-base titration was determined‚ the percent acetylsalicyclic acid in tablets by formation of a colored iron(III)-salicylate complex was determined using spectrometry‚ and then the percents from each process was compared. Acetylsalicylic acid is produced when salicylic acid and acetic
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Aspirin analysis Introduction Aspirin‚ which is also known as acetylsalicylic acid. C9H8O4 is the chemical format for Asprin. The chemical structure of aspirin: Aspirin is anti-inflammatory. Aspirin is prepared by chemical synthesis from salicylic acid‚ by acetylation with acetic anhydride. The fact that it is an acid allows us to quantify the amount of aspirin in a solution. We would do this by by using an acid-base titration. Sodium hydroxide (NaOH) will be used In this experiment as the
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