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    Sitagliptin Case Study

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    Drugs and chemicals Sitagliptin (Sita) was manufactured by Merck Sharp & Dohme Ltd (Pavia‚ Italy)‚ dissolved in saline. Gentamicin sulfate was obtained as ampoules from Memphis Co.‚ for Pharm. and Chem. Ind. (Cairo‚ Egypt). Other used chemicals were purchased from Sigma Chemical Co. (St. Louis‚ MO). Animals Animal procedures and care were in accordance with the National Institute of Health guide for the care and use of Laboratory Animals (NIH Publication No. 85-23‚ revised 1996) and were approved

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    Harvoni Case Study

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    of Harvoni is a combination of Ledipasvir and Sofosbuvir. Ledipasvir is a white to tinted‚ slightly hygroscopic crystalline solid which is Slightly solube in pH 2.3 buffer but partially insoluble in pH 4-7.5 buffers. This is Soluble in ethanol and DMSO but slightly soluble in acetone. Sofosbuvir is a white to off-white non-hygroscopic crystalline solid which is slightly soluble in water (pH1.2-7.7). this is also soluble in ethanol‚ acetone‚ 2-propanol.[4] 3.2 Drug Product: HARVONI is a fixed-dose

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    Mus Musculus

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    The house mouse (Mus musculus) is a small rodent‚ a mouse‚ one of the most numerous species of the genus Mus. The house mouse has been domesticated as the pet or fancy mouse‚ and as the laboratory mouse which is one of the most important model organisms in biology and medicine. It is by far the most commonly used genetically altered laboratory mammal. Mouse and man The sequence of the mouse genome was published in 2002. "The mouse and human genomes are very similar‚" says Dr Jackson. "There

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    know the elements of life – and how the reduction and oxidative of some of these drive bioenergetics oxidize carbon (i.e. glucose source) and reduce oxygen (electron acceptor) (CHNOPS) and iron (Fe; trace element; Fe also important to obtain cellular energy). Nutrition: CHNOPS Trace Elements: Iron (Fe)‚ Ni‚ Mg‚ Mo‚ Mn‚ Ca (important in humans due to osteoblastic activity)‚ Co Occupancy: beat out others for a spot to live‚ e.g. microbiota (normal flora) Resistance: defend against microbes‚ eukaryotes

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    Structural Effects on Stability and Reactivity. Organic Chemstry Laboratory Structural Effects on Stability and Reactivity Introduction The concepts of stability and reactivity are fundamental to understanding chemistry. In this chapter we consider first the thermodynamic definition of chemical stability. We then consider chemical kinetics (Section 3.2) and how it can provide information about reactivity. We also explore how structure influences stability and reactivity. We want to learn how

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    Buffer Preparation

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    Buffer Preparation (Gozani Lab) 1. 1 M Tris-HCl Buffers pH Volume (L) TrisBase (g) HCl (ml) pH 7.0 2 242.2 150-155 pH 7.5 2 242.2 120-125 pH 8.0 2 242.2 80-85 Autoclavable. 2. EDTA 0.5 M (pH8.0) 0.5M‚ 1L: 148 g EDTA + ~30-40 g NaOH to adjust pH (or 186 g EDTA-Na.2H2O + ~20 g NaOH) Note: pH adjusted by NaOH is essential for solubility. Autoclavable. 3. TAE DNA Electrophoresis Buffer (50 X) (2 M Tris‚ 50 mM EDTA) 2L 484 g Tris 114.2 ml glacial acetic acid 200 ml 0.5 M EDTA 8.0 To make

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    intrude in this house‚ he went on his computer and erased every bit of memory on it. Barry was furious and went to Ingrid’s house‚ he ended up breaking her window trying to get in‚ and Ingrid was afraid and stabbed his hand. Ingrid purchased a bottle of DMSO a drug injected into the blood stream. The following night‚ Ingrid was taken away for murdering Barry with poison from a White Oleander. Astrid was taken away to a foster care. She lived with a woman named Starr her 4 children and her boyfriend named

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    SYNTHESIS OF SILVER NANOPARTICLES AND ITS CYTOTOXIC EFFECT AGAINST THP-1 CANCER CELL LINE 1 * Department of Biotechnology‚ Modern College‚ Shivajinagar‚ University of Pune‚ Pune‚ India. Mrs Rebecca Thombre email rebecca.thombre@gmail.com Telephone 9822224957 020 400966725 ABSTRACT: Nanotechnology is a field of science which involves the synthesis and applications of nanoparticles. Silver nanoparticles (AgNp) have applications in various fields due to their unique

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    Miss

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    details. Part A: task 1: According to the fact situation‚ Simone is a managing director of the Youth Unlimited Pty. Ltd which is a profitable company carry on selling anti-aging products for business. The company is a proprietary company limited by shares and the managing director is also known as a chief executive officer (CEO) of the company. Also‚ it can be seen in this way‚ Youth Unlimited gives Simone a particular opportunity to in charge of the day-to-day management of the company‚ to exercise

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    Marketing

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    FOLLOWING IS TARIFF PLAN AVAILABLE WITH US. | Amount | Talktime | Validity | Description | 1500 | 1650 | Unlimited | Extra Talktime | 1000 | 1100 | unlimited | Extra Talktime | 999 | 999 | 90 Days | TalkTime 999 ( in Dedicated account and not in the main account‚ check with Airtel Customer to know how to check the dedicated balance ) + 99 A2A local minutes Free | 951 | 0 | 30 days | 3G Unlimited data usage‚ Speed Throttled at 80 kbps Post 6 GB Data usage (Before Recharging‚ Make sure that you have

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