Some may say that location and geographic is everything when it comes to building a sport super city. Others‚ like Indianapolis‚ thought that this location could never be what the 15th largest city is today. Indianapolis went from Naptown to Super City successfully using sports as a tool for economic and socio-cultural development. This transformed the entire image that has put them on the pedestal for forming sports commissions and hosting different levels of sporting events. At the time‚ Indianapolis
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Manager’s Dilemma” highlights some of the problems in store for Eli Lilly & Company‚ a major US pharmaceutical company. Eli Lilly & Co. stands to lose $10 billion in annual revenues between now and 2016 as three of its major drug patents expire. As CEO‚ John Lechleiter’s job is to find foster new drug development to replace the projected loss revenue. While other pharmaceutical companies are seeking a merger route to acquire new drugs‚ Eli Lilly One has decided to revamp the company’s operational structure
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Zoloft was the leading antidepressant drug that brought in $3.3 billion in sales before its patent expired on June 30‚ 2006. It faced branded competition from Effexor XR from Wyeth‚ Paxil and Welbutrin XL from GlaxoSmithKline‚ and Cymbalta from Eli Lilly & Co. The demand for Zoloft was inelastic before patent expiration which allowed Pfizer to set a high price for the drug. Demand then became elastic when generics entered the market post-patent expiration. The below graphs display this change
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Generally‚ patent biologics are in the cleft of expiration and there are a rise in the demand for biosimilar. Our company will start to develop biosimilar for Cetuximab (Erbitux)‚ which is an epidermal growth factor receptor (EGFR) inhibitor. Eli Lilly produces the drug in the U.S and Canada market whereas Merm KGaA produced Cetuximab for territory outside the USA and Canada. We want to pursue a biosimilar for Cetuximab to build a brand image and find finance to move to our main focus‚ which is biosimilar
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PART B. 1. One organization that I feel has the best longterm position in terms of their stock market price is Barrick Gold. http://finance.yahoo.com/q/bs?s=ABX+Balance+Sheet&annual http://www.barrick.com/investors/annual-report/financial-highlights/default.aspx The most important factor in any organization from what I learnt is how much it can pay its shareholders in dividends. Barrick gold has increased per year their annualized dividend US cents per share from 48 cents per share in 2010
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1.Intro: A pharmaceutical drug (medicine or medication and officially medicinal product) is any chemical substance formulated or compounded as single active ingredient or in combination of other pharmacologically active substance‚ it may be in a separate but packed in a single unit pack as combination product intended for internal‚ or external or for use in the medical diagnosis‚ cure‚ treatment‚ or prevention of disease. 2. History: The development of small molecule therapeutic agents for
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15.769 Manufacturing Strategy Spring 2001 Second revision of syllabus Prof. Don Rosenfield: E40-419‚ 253-1064‚ e-mail: donrose@mit.edu Teaching Assistant: Melissa Falkowski‚ Office TBD‚ mfalkow@mit.edu Manufacturing strategy examines strategy for manufacturing and operations within the firm. The course will examine how manufacturing and operations can be used as competitive weapons. Traditionally‚ these areas have been viewed as narrow‚ functional areas‚ and management of them
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Abbott Laboratories. (2012). 10-K Annual Report. Retrieved from Hoovers Database Baines‚ Donald Daemmrich‚ Arthur‚ 2011. US Healthcare Reform and the Pharmaceutical Industry. Retrieved February 28‚ 2013 from http://hbswk.hbs.edu/item/6832.html Eli Lilly & Company FDA. (2012‚ March 27). Pharmaceutical regulation. Retrieved from http://www.pharmamanufacturing.com/industrynews/2012/036.html Gassman‚ O.‚ Reepmeyer‚ G.‚ & Von Zedtwitz‚ M Herper‚ M. (2012‚ February 10). The truly staggering cost of inventing
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called Fluoxetine (more commonly known as Prozac). It is an FDA approved drug that has been widely used in treating major depression‚ obsessive-compulsive disorder (as well as BDD)‚ bulimia nervosa‚ and‚ panic disorder. Prozac is manufactured by Eli Lilly and
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drug has been uncovered. The new drug is called Ruboxistaurin or RBX. Ruboxistaurin is a bisindolymaleimid‚ it releases a protein called kinase C beta or (PKC-beta). It leads to cell growth‚ fibrosis‚ and tissue injury. (McAuley) A study done by Eli Lilly showed that Ruboxistaurin reduced the albuminuria‚ which is an indicator of diabetic nephropathy‚ by 24%. Also‚ a study done over the course of a year showed that a group of patients taking RBX had a stable kidney function and another group of patients
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