(P-gp). P-gp functions as an ATP-dependent efflux pump that transports exogenous and endogenous substrates from inside the cells to the extracellular space. Its normal expression has been identified in various human tissues‚ including intestinal epithelium‚ adrenal gland‚ placenta‚ kidney‚ liver‚ endothelial cells and testicular tissue‚ and P-gp naturally protects these organs against xenobiotics. P-gp substrates include adriamycin‚ daunorubicin‚ paclitaxel‚ vincristine‚ vinblastine‚ and imatinib
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Histo Review 1. nCAM - to block migration of neurons (it’s an antibody) 2. KNOW RBC’S EVERY STAGE‚ BRS p. 137 3. know zona glomerulosa‚ fasiculaa etc. secretions 4. in the anterior pituitary‚ know acidophils vs. basophils 5. if a drug is applied after S phase…. Stops G2 6. dynein arms have ciliary movement 7. kinesin- for fast axonal transport 8. apocrine sweat gland duct is what cell type? Simple cuboidal? 9. medial meniscus needs synovial fluid from neighboring synovial joint 10. know
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include nails‚ hair‚ and several types of sweat and sebaceous glands. Skin‚ orintegument‚consists of two distinct regions‚ the superficial epidermis and a deep dermis. The superficialepidermis is nonvascular and lined by keratinized stratified squamous epithelium with distinct cell types and cell layers. Inferior to the epidermis is the vascular dermis‚ which is characterized by dense irregular connective tissue. Beneath the dermis is the hypodermis‚ or the subcutaneous layer of connective tissue and adipose
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PATHOPHYSIOLOGY The causes or pathogenesis are usually multifactorial. Several risk factors can predispose to infection or initiate inflammation and subsequently the infectious process. Intact canal skin and cerumen production have a protective effect against infections. This is secondary to the fact that cerumen produces a pH in the ear canal that is slightly acidic. On the other hand‚ breakdown of skin integrity‚ insufficient cerumen production‚ or blockage of the ear canal with cerumen (which
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Acute bronchitis occurs during the course of an acute() viral illness‚ this includes the common cold or influenza( better known as flu). Acute bronchitis is caused by a virus on the epithelium of the bronchi which may also cause inflammation to the body. Acute bronchitis develops during the cause of a respiratory infection such as the common cold or influenza (flu). 90% of flu is caused by viruses and 10% is caused by bacteria. Chronic
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Following gingivitis‚ periodontitis considered to be the second most common infectious disease of periodontum. Gingivitis is a disease which arise when there is an inflammation in the ginigival epithelium as well in the connective tissue. When this inflammation start to cause destruction in periodontal connective tissue and the bone which support the tooth then this situation called periodontitis. The causative factor for both gingivitis and periodontitis is microbial(1). It is important to know
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Running head: (RSV) Respiratory Syncytial Virus (RSV) By Natalie Jache December 03‚ 2006 Respiratory Syncytial Virus (RSV) Introduction Respiratory Syncytial Virus (RSV) is a very common respiratory virus that displays mild cold like symptoms in adults and older children. In children under two‚ particularly those born prematurely‚ are immunocompromised‚ as well as those with heart and lung disease‚ RSV can be a potentially life threatening disease. RSV commonly occurs in epidemics
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The cardiovascular system is a closed organ system that is found within humans and other vertebrates. The heart consists of the right and left ventricle‚ right and left atrium‚ aorta‚ capillaries‚ pulmonary arteries and veins and the anterior and posterior vena cava. All of the following structures maintain the heart’s beating cycle and the circulation of blood throughout the body. Three main types of blood vessels: Arteries - Thick-walled tubes in which blood is brought from the heart to various
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MATRIX METALLOPROTEINASE EXPRESSION IN ODONTOGENIC TUMOR CELL POPULATIONS Monée Casimir‚ Dr. Jesse Mason Introduction: Ameloblastomas (AB) and calcifying epithelial odontogenic tumors (CEOT) are rare tumors thought to develop from the odontogenic epithelium and invade the jaw bone and local tissue. Keratocystic calcifying odontogenic tumors (KCOT) are also rare odontogenic tumors which are locally invasive‚ but do not invade the bone. The purpose is to compare expression of matrix metalloproteinases
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Introduction to the Senses: detect changes in the environment • General vs. specialized/attuned (some animals are better) – Human vision vs. taste/smell – Humans are diurnal and nocturnal‚ helps senses • A blind child was asked the following question: “What are the 7 wonders of the world?” – To touch‚ taste‚ see‚ hear – To feel‚ laugh‚ love – Modalities/Senses: Vision‚ Taste‚ Smell‚ Hearing‚ Touch Submodalities • Information about these senses • For vision‚ this includes light‚ color patterns
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