Module 1 ‘Introduction to Molecular Biology’ Learning Objectives (Chapter 6) Molecular Biology‚ DNA‚ chromosomes‚ and the central dogma. Understand Nucleic Acid Structure and properties (including alternate forms of DNA structure and supercoiling‚ and renaturation) Explain the nature of Prokaryotic Chromosome Understand the differences in re-association kinetics of single-copy vs. repeated sequence Understand how DNA re-association provides a measure of genome size in base pairs Functions
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in water make strong dipoles that are difficult to separate (yielding high surface tension) and greater energy to overcome when vaporized. study help site http://ocw.mit.edu/courses/physics/8-01-physics-i-classical-mechanics-fall-1999/syllabus/ Explain gas laws through KMT acc to k.m.t gasses molecules are widely separated and when pressure is applied there molecules come closer by which the volume is decrease(temperature must be constant) CHARLE’S LAW acc to k.m.t the molecules of a gas
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THE MOLECULAR BASIS OF INHERITANCE I. History A. Discovery of “transformation” – a change in genotype and phenotype due to the uptake of external DNA by a cell 1. Griffith 1920s did experiments with Streptococcus pneumoniae (p294 fig16.2) a. took two strains of S. pneumoniae‚ one virulent‚ one not b. heat killed virulent strain‚ then mixed them with the living nonvirulent strain c. living nonvirulent strain became virulent d. nonvirulent strain took on virulent strain’s DNA became virulent
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Molecular Biology 344 fall 2012 A Johnson Due 9/11/12 as hard copy at the beginning of lecture Problem Set 1 1. Look carefully at the structures of the two molecules shown below. a. What would you expect to happen if you added ddCTP (shown in a) to a DNA synthesis reaction in vitro in large excess over the concentration of deoxycytidine triphosphate (dCTP)? How will this affect the pattern of bands on the sequencing gel? The ddCTP lacks the OH‚ which is required for elongation
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The Mausoleum at Halicarnassus was built in the capital city of Caria‚ Halicarnassus‚ which was present-day Bodrum‚ Turkey. It was built between the years 353 B.C. and 350 B.C. After construction had started‚ the Mausoleum could have faced destruction several times. The Rhodians’ land had been conquered by Mausolus‚ and they soon learned of his death. They rebelled and sent ships to capture Halicarnassus. They were defeated and the tomb was never harmed. It was untouched when Alexander the Great
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THE ROLE OF PROTEIN MISFOLDING AND AGGREGATION IN BSE When a protein misfolds it changes its behavior and function. If it becomes hydrophobic after once being polar. The properties and functionality of the protein are no longer useful to the organism and disaster results. PrPSc is hydrophobic‚ it avoids water inside of the cell…it attracts and attaches other proteins to misfolds and become hydrophobic …Misfolding spreads because the PrPSc act as chaperone proteins to convert PrPc TO PrPSc and
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I. Purpose The purpose of this lab is to determine the molecular mass of a volatile liquid. II. Procedure • Place a cork with a small hole in it inside of a test tube and find the weight of the two together using a sensitive balance. • Pour 0.5 mL of the unknown volatile liquid into the test tube‚ insert the cork‚ and place the tube into boiling hot water while keeping the cork above water level. As the gas evaporates‚ excess gas will be released throughout the whole in the cork. Keep the test
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Introduction There has been much new advancement in the nano-technology field on a international level in recent years. The new advancements have drawn a increasing interest in nanometer scale surface coating. Ultra thin film coatings can be used in a wide range of applications as lubricants‚ anti-stiction layers‚ molecular glues‚ coupling agents or adhesion layers. The mentioned molecular coatings are used to modify material surface properties. The traditional coating deposition methods consist
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mechanisms that regulate cellular senescence‚ organismal ageing‚ and species-specific lifespan depend on a synergy of pathways that are multifactorial and extremely complex‚ though not yet completely understood. Recently‚ the development of new molecular techniques has elucidated‚ at least in part‚ the primary pathways involved in ageing. In parallel with the search to uncover the factors that control ageing is the endeavor to discover methods of extending lifespan‚ in hopes of living both youthfully
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an arrangement of guidelines by which a nation or state is run. The Australian Constitution sets up the creation of the Australian Parliament‚ and depicts how Parliament works‚ what powers it has‚ how elected and state Parliaments share control‚ and the parts of the Executive Government and the High Court (Office‚ 2017). Australia has three levels of government which include Federal‚ state and local. The federal parliament has the ability to make laws for the entire of Australia.
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