Introduction: The pharmacokinetics of a drug describes the journey of a drug through the body i.e. its absorption‚ bioavailability‚ distribution‚ metabolism and excretion. Opioids are substances (endogenous or synthetic)‚ which produce ‘opiate-like effects’. Opiates are alkaloids derived from the Papaver somniferum poppy e.g. Morphine‚ Codeine (a morphine-like agonist) and Methadone (a synthetic analogue of morphine) and are primarily used as analgesics.[1] Discussion: Morphine has a 4-ring structure
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Introduction The American Chemical Society databases were investigated through Scifinder Scholar Version X to find any information about Butyl 2-Cyano-(3‚5 dichloro-phenyl)-2-propenoate. There was no previous information present. Then‚ the microscale synthesis and characterization of Butyl 2-Cyano-(3‚5 dichloro-phenyl)-2-propenoate was conducted with the base catalyzed Knoevengael condensation of the butyl cyanoacetate and corresponding aldehyde (gkharas/235_14F/235_14F_Lab_2.pdf) and analysis. The elemental
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Protein Synthesis Worksheet 1. 2. a. Protein synthesis began in the nucleus. b. Chromatin is a diffuse mass located in the nucleus where genetic material is found. c. A gene is a sequence of nucleotides‚ it is important because they form the template and these templates are used for synthesizing proteins. 3. a. Transcription is the first step of protein synthesis it uses a sequence of DNA nucleotides to produce a sequence of RNA nucleotide. b. RNA polymerase bonds to RNA nucleotides together
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The goal of this experiment was to synthesize dibenzalacetone by aldol synthesis. The name ’Aldol synthesis’ was taken from the words ’aldehyde and alcohol’. This is because the product of this reaction contains both an aldehyde and alcohol. The carbon-carbon bond-forming reaction is referred to as aldol addition. An aldol condensation yields many species of products if the reactant is more than one. Therefore‚ the aldehyde has to react with itself to yield one product. Procedure: Followed according
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Synthesis Paper Dawn I Gaunt Introduction to Graduate Studies 5093 3 October 2014 Social and natural sciences differ dramatically‚ but they both play very important roles. Social sciences are concentrated on the human response to the environments that we ourselves have created and the natural environment. Social science experiments‚ which are documented by human observation‚ provide no absolutes due to their methods of data collection and analysis. The observations‚ the sample groups‚ and
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SYNTHESIS OF SILVER NANOPARTICLES AND ITS CYTOTOXIC EFFECT AGAINST THP-1 CANCER CELL LINE 1 * Department of Biotechnology‚ Modern College‚ Shivajinagar‚ University of Pune‚ Pune‚ India. Mrs Rebecca Thombre email rebecca.thombre@gmail.com Telephone 9822224957 020 400966725 ABSTRACT: Nanotechnology is a field of science which involves the synthesis and applications of nanoparticles. Silver nanoparticles (AgNp) have applications in various fields due to their unique
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CHEM 3125 Experiment 4: Multistep synthesis of tetraphenylcyclopentadienone Overall Synthesis: CHEMICALS: wk 1: thiamine hydrochloride (1 g/student)‚ 95% ethanol (8 mls/ student)‚ 2M NaOH (5 mls/student)‚ benzaldehyde (4 mls/student) wk 2: 95% ethanol (30 mls/student) wk 3: acetic acid (6 mls/student)‚ ammonium nitrate (1 g/student)‚ 0.1g/ml cupric acetate (1.5 mls/student)‚ dichloromethane (6 mls/ student)‚ 30% acetone in heptanes (3 mls/student)‚ 95% ethanol (20 mls/student) wk 4:
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0.22g (percent yield of 86.9%). The percent yield after recrystallization‚ was 80.9%. INTRODUCTION The goal of this experiment was the synthesis of 3-nitrochalcone from 3-nitrobenzaldehyde and acetophenone as shown in Figure 1: Figure 1: Synthesis of 3-Nitrochalcone from 3-Nitrobenzaldehyde and Acetophenone Source: cnx.org The mechanism for the synthesis of 3-nitrochalcone is presented in Figure 2. The alpha carbon on the acetophenone is deprotonated‚ followed by the attack of the alpha carbon
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Experiment 13: Synthesis of 1-Bromobutane An SN2 Reaction Experiment #13: Synthesis of 1-Bromobutane an SN2 Reaction Introduction: In order to synthesize 1-Bromobutane an alkyl halide must be present to undergo a nucleophilic substitution reaction of an alcohol. Since 1-butanol is a primary substrate it will undergo an SN2 reaction with sodium bromide in order to convert the alcohol group to water which is a better leaving group and will in the end produce 1-bromobutane. Experimentally
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Synthesis of 1-bromobutane from 1-Butanol using the SN2 Reaction Abstract: The objective of this experiment is designed to study the synthesis of 1-bromobutane from 1 butanol using a SN2 reaction.. The product will then be analyzed using a flamed loop test by use of fire. Reaction Mechanism: CH3CH2CH2CH2—OH H+ CH3CH2CH2CH2— +OH2 Br- CH3CH2CH2CH2—Br + H2O 1-butanol
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