and the discovery of DNA Ralf Dahm* Max Planck Institute for Developmental Biology‚ Department 3 – Genetics‚ Spemannstr. 35/III‚ D-72076 Tubingen‚ Germany ¨ Received for publication 5 October 2004‚ revised 17 November 2004‚ accepted 20 November 2004 Available online 21 December 2004 Abstract Over the past 60 years‚ DNA has risen from being an obscure molecule with presumed accessory or structural functions inside the nucleus to the icon of modern bioscience. The story of DNA often seems to begin
Premium DNA
An Introduction to DNA microarrays Rebecca Fry‚ Ph.D. http://www.buffalo.edu/UBT/UBT What is a DNA Microarray? genes or gene fragments attached to a substrate (glass) Tens of thousands of spots Hybridized slide Two dyes Image analyzed 1 The Beginnings of Microarray Technology Lockhart et al.‚ 1996 Nature Biotechnology “Expression monitoring by hybridisation to high-density oligonucleotide arrays” Schena et al.‚ 1995 Science “Quantitative monitoring of gene expression
Premium DNA Gene expression
forefront is DNA vaccination. DNA vaccines are bacterial plasmids that encode the polypeptide sequence
Premium Immune system Vaccine
main source of evidence. Notoriously unreliable‚ these techniques have since faded away to the stunning reliability of DNA forensics. In 1984‚ British geneticist Alec Jeffreys of the University of Leicester discovered an interesting new marker in the human genome. Most DNA information is the same in every human‚ but the junk code between genes is unique to every person. Junk DNA used for investigative purposes can be found in blood‚ saliva‚ perspiration‚ sexual fluid‚ skin tissue‚ bone marrow‚ dental
Free DNA
Experiment 2: Extraction – Evaluation Summary Labs reports must be typed and chemical structures must be drawn with ChemDraw. Report must not exceed three pages (including this page). Page limit does not include any attached spectra or references. ** Deductions for hand written report/structures and exceeding page limit ** Report Breakdown Data/Results: _________________ /10 Discussion: _________________ /10 Report Total: _________________ /20 Other Lab Marks
Premium Solubility Fatty acid Solvent
SOLVENT EXTRACTION Solvent extraction‚ also known as liquid extraction and partitioning‚ is a method to separate compounds based on their relative solubility in two different immiscible liquid‚ usually water and organic solvent. It is an extraction from one liquid phase to another liquid phrase. Liquid extraction is a basic technique in chemical laboratories‚ where it is performed using a separator funnel. This type of process is commonly performed after a chemical reaction as part of the work-up
Premium Acetic acid Solubility Solvent
Forensic DNA Evidence DNA has become one of the most accurate tools used in law enforcement in determining guilt or innocence. DNA is different in all people it is our “genetic blueprint.” DNA is so significant to law enforcement because DNA left at a crime scene can be collected and tested to see if there is a match. It is unique because it ensures accuracy and fairness. The initial use of DNA began in Britain in 1986; the FBI used it for the first time in the United States two years
Premium DNA
Extraction of metals The History of Metals. Metals have been used by people for many thousands of years. Gold and silver‚ found as native metal‚ were used both as jewellery and as a status symbol - nothing new there. These metals were known in the Stone Age‚ but gold and silver are too soft to be used as tools. The first really useful metal to be discovered was bronze. This began the Bronze Age. Bronze was used extensively for tools and weapons in Asia and Africa from 4‚500 B.C. (6‚500 years
Premium Oxygen Metal Iron
Extraction Report For experience 4c we were supposed to determine which one is the organic layer in three different tubes that has two layers. To determine which is aqueous (water) or organic‚ I used the technique of adding droplets of water to each tube. If the layer is water‚ then the drops of added water will dissolve in the aqueous layer and increase it’s volume. If the added water form droplets or a new layer‚ then it is the organic layer. Tube 1 (water and n-butyl chloride)‚ after adding
Premium Water Liquid Sodium chloride
Extraction of Caffeine from Tea Leaves Jaybee Balilea‚ Sharmaine Baysic‚ and Maria Anjelette Patricia Belen 3BIO7‚ Department of Biology‚ University of Santo Tomas‚ Manila‚ Philippines Abstract Extraction is a technique for isolating and purifying organic substances. In this technique‚ a solution is combined thoroughly with a second solvent that is immiscible with the first solvent. The solute is extracted from one solvent into the other because it is more soluble in the second solvent
Premium Solubility Solvent Tea