Mechanisms of Acetaminophen-lnduced Liver Necrosis By Jack A. Hinson‚ Dean W. Roberts‚ and Laura P. James Acetaminophen (paracetamol‚ N-acetyl-p-aminophenol; APAP) is widely used as analgesic and antipyretic drug. At therapeutic doses‚ acetaminophen is safe to be used. Acetaminophen other than aspirin and ibuprofen has only weak anti-inflammatory properties. At higher doses‚ acetaminophen produces a centrilobular hepatic necrosis that can be fatal. Acetaminophen-lnduced Hepatotoxicity Observation/
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Week One Consumerism Brand – refers to the name and iconography of a product‚ replaces interpersonal communication with the producer‚ attempts to overlay transformational values for the consumer. Target Audience Pioneer advertising Competitive advertising Comparative advertising Subliminal advertising Materialism Social marketing – kim dotcom pastiche Green marketing Culture of Commodity ‘Commodity fetishism’ (Karl Marx) Example: price tag Uganda Week Two Capitalism – the
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high fuel prices‚ problems parking‚ decreased emphasis on price‚ smaller families‚ and an increase in the number of working women have all contributed to increased fragmentation and overall demand for small cars in France. For instance‚ 1995 saw small cars account for 43.7% of all the new cars sold there. This increased fragmentation has contributed to the difficulty in finding an ideal non-traditional segment in which to target and market the Ka. Given their backward situation‚ Ford commissioned
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experiments in many developing countries. India is one of the countries where it was most successful. There were three basic elements in the method of the Green Revolution Continuing expansion of farming areas Double-cropping in the existing farmland Using seeds with improved genetics. The area of land under cultivation was being increased from 1947 itself. But this was not enough to meet the
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countries wanted this land to expand their empires. Eventually‚ this war will lay the groundwork for the struggles between the colonists and Great Britain‚ resulting in the American Revolution. Even though the Ohio Valley was made up of a lot of good farmland‚ the French weren’t as interested in the land as they were in the fur trade with the Indians. They wanted to set outposts along the Mississippi River
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to be one with nature‚ with no human playmates‚ but rather she is more than happy with animal companions throughout the farm and swampland. The little girl’s excitement came from trying to find the cow Mistress Mooley as she wandered amongst the farmland in her own version of hide and seek and walking alongside her. The rising action of the story comes when Sylvia is faced with a startling encounter of a man lost on her farm‚ coincidently‚ the only male appearing throughout the entire story. She
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Hard and soft river defences on the Mississippi The dams in the Mississippi river are a hard flood defence. There are two different types of dams on the Mississippi River‚ wing dams and closing dams. Wing dams are built close together with brush and stone structures that extend from the river bank to the channel and closing dams are used to block connections between the main channel and side channels of the floodplains. The advantages of building dams on the Mississippi are that they enhance the
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normal. The economy; due to the shortage of land and people‚ people were out of pay and prices of food went up. Due to many deaths‚ there were shortages of goods and then a rise in prices. The prices on wheat‚ cheese‚ and meat went up. Majority of farmland was left with no farmer so the food was there to rot. Due to that‚ people could not provide food for themselves and they had to buy food even though the prices went up; the consumption of meat went up as well. The plague affected Europe’s community
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philosophies. Also‚ it is a metaphysical movement that questions all the fundamentals of literature that came before in the romanticism‚ modernism‚ and imagism movements. Although postmodernism literature has no set definition‚ common traits include fragmentation‚ black humor‚ and challenging the borders of decency which is exemplified in Eugene O’Neill’s “Long Day’s Journey Into Night.” “Long Day’s Journey Into Night” is fragmented in the sense that O’Neill deliberately puts the conversations of the
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In order to understand the extent to which Old World ideals are embedded into the fabric of our own institutions it is necessary to search for the truths about the Western discoverers amongst the plethora of myths and nationalistic propaganda. The Columbian legacy is one of discovery and dominion over native peoples‚ the ecological environments that natives were participants of‚ and all natural resources within the new found American paradise. And while it can be said that tribes of humans dominating
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