substitution happens when the initially formed intermediate expels one of the substitutes originally bonded to the carbonyl carbon leading to the formation of a new carbonyl compound. In this experiment‚ the specific nucleophilic acyl substitution is esterification. It occurs when a carboxylic acid in salicylic acid and an alcohol combine in a reaction to produce an ester. Figure 11.4. Mechanisms on the formation of aspirin Phosphoric acid protonates the carbonyl oxygen atom (C=O) of the anhydride
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Figure 1: Rf Values. Figure 2: IMFs In Each Structure. 3. What is the difference between a’smart’ and a’smart’? Write a paragraph that describes how each compound is attracted to each element and silica. The first eluent (A)‚ 9-fluorenone greatest IMFs are dipole-dipoles‚ although silica allows for short dipole-dipole interactions‚ which is possible because of its polar regions. This relationship is exemplified by 9-fluorenone?s high Rf values‚ and a strong affinity towards the stationary.
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Experiment 01/25/2013 CHM Lab- 2211 Sec 0016 Instructor: Jennifer Reed Introduction: Commonly used as Aspirin‚ acetylsalicylic acid is an analgesic (pain reliever)‚ which is one of the products of the esterification reaction between salicylic acid and acetic anhydride. This esterification occurs since the hydroxyl group from the salicylic acid reacts with acetic anhydride to form an ester. In this experiment‚ we will be able to recreate this acid catalyzed reaction‚ using sulfuric acid as our
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Introduction: This experiment involves an extraction of a natural product using the techniques of steam distillation. The principle component of oil of cloves is an aromatic compound‚ which is identified by thin layer chromatography (TLC). Eugenol is widely used in dentistry‚ due to its analgesic‚ antiseptic balsamic qualities. It is ideal for curative for pulp hyperemia (the soft‚ sensitive substance underneath the enamel and dentine of a tooth) and pulp its. In dentistry eugenol is also used to
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product results in a racemic mixture of benzoin. If both carbonyl groups are reduced‚ the product results in a meso-hydrobenzion or a racemic mixture of hydrobenzion. The goal of the experiment is for the student to reduce benzil and use melting point‚ TLC‚ and IR to determine the stereochemistry of the resulting product. Figure 2: Benzil reduction mechanism: Key experimental details‚ observations and results: The initial reaction solution including the 1.011g of benzil and 10ml of 95% ethanol
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The synthesis of meso-1‚2-dibromo-1‚2-diphenylethane was successful as the final product of the experiment had the same physical properties of the theoretical properties‚ which were determined by TLC and melting point. The synthesis of diphenylacetylene was also successful‚ as TLC and the melting point both proved its identity‚ however the UV-vis analysis went awry due to a procedural mistake‚ making the analysis unusable. The most important learning outcome of Experiment 6 was understanding
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Chemistry 207 (Lab # 1) 9/11/12 Experiment #1: Cooperative Identification of an Organic Solid A. What needs to be done: In this lab‚ one will identify the identity of a colorless organic solid by experimentally finding the physical properties of the solid. Such properties include melting point‚ mixed melting point‚ and IR spectrum. With these properties‚ one will be able to compare their results of the organic solid to see if any other classmates have the same unknown sample. B. Timeline:
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Introduction The word inflammation comes from a Latin word “Inflammare” which means “to set on fire” [1]. Inflammation is a protective response done by our body to protect itself from injury‚ foreign microorganisms as well as initiate healing and repair process. However‚ inflammation can also be potentially harmful to our body because of the chemicals involve in inflammation process which are capable to destroy and injure normal tissues. The components of inflammatory process are white blood cells
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Final Year Project Progress Report Title: Fat Content Analysis and Characterization of Food Class and Group No. : AS114103/2A1 Student Names : Chan Hoi Ching (120586347) : Chan Wai Yi (120464356) : Cheung Kit Cheung(120552694) : Lam Chi Ching (120224281) : Lam Pik Shan (120181829)
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Identification of an Adulterated Herb The purpose of this lab is to analyze the volatile oils of some herbs through TLC testing and then identify the adulterant in a sample. Unfortunately‚ we ran out of time to complete the lab; however‚ we were able to get through most of it‚ and were only missing the adulterant. The first step to identify our unknown samples was to create TLC plates that should results with each known compound and 95% hexane: 5% ethyl acetate‚ 90% hexane: 10% ethyl acetate‚
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