ineffective. In order to help resolve the crisis‚ antibiotics were found through screenings of soil microorganisms. However‚ soil microorganism’s antibiotics were depleted by the 1960s and their antibiotic effects were unable to be replicated through synthesis. In this experiment‚ the researchers developed numerous methods to cultivate uncultured organisms in their environment. The goal of this experiment was to find antimicrobials in the uncultured soil. Through this successful experiment‚ the researchers
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COLUMN AND THIN LAYER CHROMATOGRAPHY Mark Paul P. Pastrana‚ Mariah Ericka M. Patawaran‚ Princess Juneire M. Peligro‚ Francisco Q. Pua III‚ Rose Anne L. Quyo and Janille P. Ragpa Group 8 2B Medical Technology Organic Chemistry Laboratory ABSTRACT The main objectives were to separate the colored components of malunggay leaves by means of column chromatography‚ as well as to determine the purity of the components using thin layer chromatography (TLC) and measure the Rf values of the colored
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Title: That immediate past experiences of being presented with either images of animals or faces influence what the subject perceives in the ambiguous figure in that if presented with animals‚ the subject would see a rat‚ and subjects shown the faces will see a man’s face. Abstract: The primary purpose of this activity was to investigate immediate past experiences and how they play a part in visual perception. The basic method involved participants being divided into three pairs to be tested
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follows a semi microscale technique even a small amount of lost product yields a great loss in the yield 4. These sources of error could be minimized by doing a larger reflux in order to increase the yield. However‚ as the purpose was to simply synthesis SnI4 in order to identify the stable oxidation states (the melting point range requires very little product) it would be advantageous to use the current method. This is due to the smaller quantity of materials needed for this type of reflux‚ thus
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RECRYSTALLIZATION OF ACETANILIDE De Ocampo‚ Yves Aaron Julian Q.‚ Dela Vega‚ Roderick B. Jr.‚ Elguira‚ Cedric Tristan D. Enriquez‚ Joanne B.‚ Gabat‚ John Elliot N. Group 5 2D-Medical Technology Faculty of Pharmacy‚ University of Santo Tomas ABSTRACT The experiment was executed in order to purify compounds through recrystallization. Recrystallization is the primary used operation for purifying solid organic compounds that differ in solubility at different temperature. It is a process of dissolving
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Reactivity of Halide Ions PURPOSE The purpose of this experiment is to observe the reactions of halide ions with different reagents by mixing them together. Materials 0.1 M AgNO3 0.1 M NaCl 0.1 M NaF 0.2 M KBr 0.2 M Na2S2O3 3% Starch Solution 4.0 M NH3 (aq) 5% NaClO (commercial bleach) 24 – well microplate thin – stemmed pipettes‚ 12 Safety DATA |PARTS |INITIAL MASS |FINAL MASS |CHANGE IN MASS | |
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Rebecca Boreham 7/1/14 Chem 2423 Experiment #5 Synthesis of Aspirin Elizabeth Ajasa Kaylee Seymour Lauren Hatfield Suveda Perikala Introduction/ Purpose Aspirin is the most commonly used drug in the United States. Forty million pounds are produced each year. The chemical name for aspirin is Acetylsalicylic acid. Aspirin is a pain reliever and a fever reducer. Aspirin originated from the bark of a White Willow Tree. Chewing the bark however is extremely acidicand irritates the mucous membranes
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Aspirin Synthesis Introduction Out of all the pharmaceutical drugs in the worlds‚ aspirin is made the most. Any potential pharmacist must be familiar with synthesizing the drug. The goal of this lab is to synthesize as much pure aspirin as possible. The reactants‚ acetyl anhydride and salicylic acid‚ must react in phosphoric acid. With phosphoric acid as a catalyst‚ the reaction yields aspirin and acetic acid. The equation for the reaction is as follows: “(CH3CO)2O + HOC6H4COOH □(→┴yields ) CH3CO2C6H4CO2H
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The structure and synthesis of TPC is outlined in Scheme 1. Briefly‚ the compound 1 was synthesized as per literature procedure. 2 was synthesized by reacting 1-methy pyrazole-4-boronic pinacol ester with 1 by suzuki-coupling‚ the final product TPC was synthesized by treating with malononitrile in the presence of piperidine as a base and ethanol as solvent. The detailed synthesis procedure given in the experimental section. The structure and purity of TPC was unambiguously confirmed by 1H and 13C
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If I want to target the peptide to different compartments‚ I would use specific signal sequences or uptake-targeting sequences encoded into my peptide. Signal sequences contain information that will target the peptide to a particular organelle. The information is usually encoded within amino acid sequences of the protein itself‚ usually within the 20-50 amino acids. Also‚ each organelle has specific set of receptors that bind only to the specific signal sequences‚ thus making sure of target specificity
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