William son Eth er Synth esis Introduction In this reaction‚ an alcohol is deprotonated to form a good nucleophile‚ which then attacks the electrophile methyl iodide to form an ether. Tetrabutylammonium bromide‚ a phase transfer catalyst‚ is used to carry ions back and forth between the organic phase and the aqueous phase. OH O NaOH + NaI + H2O CH3I Before coming to lab‚ please review the following techniques: "Reluxing a reaction‚" "Extraction and washing‚" "Drying an Organic Solvent‚" "Evaporating
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Procedure The procedure stated in Chem 2120 experiment 6 Williamson Ether Synthesis of Phenacetin laboratory manual was followed without any major changes. Data and results Compound Amount used MW (g/mol) Moles Stoichiometry/Comments acetaminophen 0.354 g 151.16 2.34 x 10-3 limiting reagent ethyl iodide 0.3mL 155.97 3.75 x 10-3 1.6 equiv ’s sodium ethoxide 2.6mL 68.05 3.3 x 10-2 catalyst‚ reaction solvent crude product obtained: phenacetin 0.32g
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The goals of this experiment are to determine if the products derived from amide synthesis and Williamson Ether Synthesis are identical‚ and if one of the synthetic routes is more advantageous than the other. In Part 1‚ an attempt to synthesize acteophenetidin crystals by amide synthesis was made. We began by removing the colored impurities from the p-Phenetidine (reddish-brown) by placing 2g of the sample in 38 mL of hydrochloric acid and heating the solution to boiling point. Upon reaching just
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simplest way to synthesize an ether is to have an alkoxide react with a primary haloalkane or a sulfonate ester under typical SN2 conditions. The scientist who developed this reaction‚ Alexander W. Williamson‚ was a professor at University College in London in the latter part of the 1800’s. This reaction has been around a while! Secondary haloalkanes and sulfonate esters are occasionally used in the Williamson ether synthesis but the yields are often poor. The ether prepared in this experiment is
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I. INTRODUCTION Synthesis Acetylsalicylic acid is an acetyl derivative of salicylic acid which appears as a white and crystalline and a weakly acidic substance with a melting point of 135°C and is also known to be aspirin. It is one of the most widely used drugs that can lower fever and is used as a painkiller. According to (Escobel‚ 2011)‚ Aspirin is synthesized through the reaction of salicylic acid with acetyl anhydride that causes a chemical reaction that turns salicylic acid’s hydroxyl group
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II. Synthesis This activity helps me to understand myself better by knowing what people think of me. It aims to foster self-awareness and self-improvement. I found out that my family thinks that I am a responsible person in terms of sense of responsibility. But my brother thinks I’m immature. In terms of duties at home‚ my mother and father understand that I don’t perform my duties because I’m busy with my studies. My sister thinks it too but she justified that I perform when I’m not busy. When
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Synthesis The idea of gender wage discrimination being widely practiced in the United States today is a difficult concept for many to swallow. With the Equal Pay Act of 1963 and Title VII of the Civil Rights Act of 1964‚ the realization of the existence of the gender wage gap surprises many Americans. These authors bring to the forefront the idea that there is more to the gender wage gap then just companies discriminating against women and minorities. They sight many sources with defined data
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different approach by targeting not everyone but only few saying‚ “…not merely the heights to which some will climb or the difficulties others will endure.” When combining these two statements you can see how they synthesis; In other words‚ the lower class of America will either suffer from being under skilled or replaced by technology‚ while the successful class of America will become known as “The Untouchables”‚ meaning they will be so specialized that they will not be replaced. These articles appeal
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Synthesis “The kingdom of heaven is within the mind of a person‚ not within the collective mindlessness of a crowd.” In the articles‚ “The Only True God and Jesus Christ Whom He Hath Sent”‚ by Jeffery R. Holland and “Propaganda under a dictatorship”‚ by Aldous Huxley are two totally different topics. This paper will be a breaking down of the two articles and finding the similarities between the two of them. It will be interesting‚ but nothing is impossible. The two topics are Hitler wanting so
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Bankruptcy: Its Prediction and Accounting Indicators One major assumption in accounting is the Going Concern. It states that an accounting entity is viewed as continuing in operation indefinitely‚ thus‚ financial statements are normally prepared in the assumption that the entity will continue its operations for the forseeable future. But then it is inevitable that one shall come to an end. So if there is evidence that the entity’s operations are to be terminated‚ the going concern assumption
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