expressions The Expressions Company began in 1988 as The Expressions Card and Stationery Shop‚ offering greeting cards and other paper products exclusively distributed by Sterling Paper. Two decades later‚ The Expressions store has grown to over 40 branches nationwide and has expanded its merchandise to include complete lines of school and office supplies‚ gift and novelty items‚ computer supplies and reading materials‚ living up to its current positioning as "Your affordable school and office
Premium Ecology Luzon Philippines
The activities of MDM2 are highly controlled by extracellular and intracellular stress signals.These signals include genotoxic stress signals‚ ribosomal stress‚ oncogenic activation‚ and psychological stress signals. They function through distinct signalling pathways to regulate the ability of MDM2 to bind with p53‚ MDM2 E3 ubiquitin ligase activity‚ and the cellular localization of MDM2. The ability of MDM2 to export p53 to cytoplasm is blocked by the phosphorylation of MDM2 at these two positions
Premium Protein DNA Gene
Results and Discussions Cbes-AXE2 encodes a novel acetyl xylan esterase The CAZy database has grouped esterases acting on carbohydrates into 16 different families of carbohydrate esterases (CEs). AXEs (EC 3.1.1.72) acting on acetylated xylan are distributed in only 8 families – CE1-7 and 16. Among these‚ other than CE4‚ all other CEs belong to serine esterase and have the prototype catalytic triad Ser-His-Asp (Glu). Genralyy‚ the catalytic serine of the triad lies in a conserved motif of either
Premium DNA Protein Gene
and the assurance to a higher standard of future for their children. However‚ this may not be accurate for all families. One or both of the parents have chosen to work overseas because of the worsening economic condition in the Philippines. From genes to bequests‚ parents have important influences on the income‚ health and general living standards of their children as adults (Ermisch‚ 2003). Parents either working within the country or overseas influence their children in countless ways. They create
Free Philippines
The Roux Lab is one of the labs at Sanford Research that focuses on proteins. The goal of the lab is to map the proteins of the nuclear envelope using BioID. This may sound like a simple goal but figuring out where each protein is located but it is a daunting task. With the lab trying to map the proteins‚ it is necessary to develop efficient ways of seeing how proteins interact. In the past years of the Roux lab‚ they have developed a system to see which proteins interact with other proteins
Premium DNA Gene Protein
The process by which DNA turns into polypeptides is a complicated and long. Two main steps in changing the DNA into a polypeptide are transcription and translation‚ with transcription coming first. The process first starts in the nucleus of the cell. The DNA begins to unfold with the help of a helicase. During the transcription phase of the change‚ strands of DNA begin to unwind and the complementary mRNA is made or transcribed. The way they do this is by using the common pairs of DNA triplet bases
Premium DNA Gene Protein
It is generally assumed that the toxicity of streptozotocin is dependent upon the DNA alkylating activity of its methylnimethylnitrosourea moiety‚ especially at the O6 position of guanine. The transfer of the methyl group from streptozotocin to the DNA molecule causes damage‚ which along a defined chain of events‚ results in the fragmentation of the DNA. Protein glycosylation may be an additional damaging factor . In the attempt to repair DNA‚ poly(ADP-ribose) polymerase (PARP) is overstimulated
Premium DNA Gene Protein
Formaldehyde as a model protein crosslinking reagent. Understanding protein-protein interactions is becoming a vital study for application in the development of new age pharmaceuticals and utilization in diagnostic models. The overall aim is to gain an insight into the function and role of individual proteins with specific interest on how they react in cells‚ (Toews et al. 2008). The biopharma industry in Ireland is becoming a booming success for the economy therefore a complete understanding of
Premium DNA Gene Protein
Introduction This study approaches the understanding of the autosomal recessive “mini-muscle” phenotype in mice. Smaller body size and muscles as well as increased maximal oxygen intake are observed in mice with the “mini-muscle” phenotype. This observation raises an issue about why the selectively bred mice with the “mini-muscle” phenotype have reduced triceps and thigh muscle mass as they are able to cover greater distances; due to faster running speed‚ on an activity wheel compared to normal mice
Premium Gene Obesity Nutrition
Melatonin is a naturally occurring hormone in humans that is mainly synthesised in the pineal gland‚ but can also be formed in other parts of the body‚ such as the eyes‚ the GIT‚ bone marrow‚ lymphocytes‚ and skin (Cutando et al.‚ 2012). It is not a ‘traditional’ hormone in the sense that it does not have specific organs that it is synthesised in or that it targets (Cutando et al. 2012). One of the roles of melatonin is its involvement in various regulatory activities‚ such as the light/dark cycle
Premium Cancer Oncology Immune system