Chapter 10 Foundations of Genetics Lecture Notes 1 Foundations of Genetics Mendel and the Garden pea The father of modern Genetics is Gregor Mendel. Gregor Mendel (1822-1884) was an Austrian monk who lived in a monastery where the experiments with the garden pea were performed. Mendel’s work with the garden pea was the fundamental study which unveiled the laws that govern genetics and heredity. Mendel was the first to use the scientific method in a very systematic and analysed his results
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Genetic Engineering is the changing of an organism’s genetic‚ or hereditary‚ makeup to get rid of unwanted characteristics or to make wanted new ones. Genetic engineering is used to increase plant and animal food production. It is also used to help dispose of industrial wastes‚ to diagnose disease‚ improve medical treatment‚ and produce vaccines and other useful drugs. Genetic engineering techniques include the selective breeding of plants and animals‚ and hybridization‚ which is the reproduction
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1. Genetic cloning is one way of studying the specific proteins involved in cell division. A gene contains the instructions for how to make a protein. By mutating a gene‚ the protein’s shape‚ size and function could all be affected. Mutating a gene changes its instructions. Once a mutated gene is created and incorporated into a cell’s DNA‚ the cell replicates‚ creating many cells containing the mutant gene. The cells with the changed gene can then be compared to normal cells. For starters‚ you must
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Genetics Review DNA (Deoxyribonucleic Acid): Stored inside chromosomes and contain all instructions for life It is made up of Ribose (sugar)‚ phosphate‚ and when of 4 Nitrogenous bases (Adenine‚ Thymine‚ Guanine and Cytosine) A Nucleotide consists of a Phosphate molecule‚ a sugar molecule‚ and a Nitrogenous base pair The nitrogenous bases always pair up AT and CG Each human has 46 chromosomes 23 pairs in total 1 pair sex chromosomes (that define your sex‚ male XX‚ female XY) 22
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Genetic Technology and Personalized Medicine Nicole Williams Dr. Kennedy SCI 115 November 4‚ 2011 A patient is being treated for breast cancer. The medicine usually involved to treat this disease is Chemo Therapy and radiation. It works for some‚ some it does not. So what other alternative is there for patients with this illness? Currently in the works is the idea to study an individual patient’s genotype to get a better understanding of what medication‚ therapy‚ treatment‚ will actually
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have only one X chromosome)‚ one altered copy of the gene in each cell causes the condition. In females (who have two X chromosomes)‚ a mutation would have to occur in both copies of the gene to cause the disorder. What is the role of genetic testing ? - Genetic testing for Hemophilia A&B is to check for mutations within the genes. DNA testing would be the most accurate test for identifying carriers. A blood sample from a male family member with hemophilia is checked first. Then‚ a blood sample
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Mendelian Genetics Introduction In 1865 an Austrian monk‚ Gregor Mendel‚ presented the results of painstaking experiments on the inheritance of the garden pea. Those results were heard‚ but not understood‚ by Mendel’s audience. In 1866‚ Mendel published his results in an obscure German journal. The result of this was that Mendel’s work was ignored and forgotten. Mendel died in 1884 without knowing the pivotal role his work would play in founding the modern discipline of genetics. By 1899‚ some
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Epigenome controls the genetics of the body by determining how cells differ from one another. The cells in our body all have the same genes‚ but it’s the epigenome that differentiate the cells to become skin cells‚ nose cells‚ liver cells‚ and heart cells. Skin cells are different from nose cells because the certain set of genes are turned off by the epigenome to express what that cell will become. For example in the video the fat mice with yellow coat have the agouti gene. When the mother is given
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organism’s genetic makeup‚ whereas phenotype refers to an organism’s actual physical traits. Being that genotype describes an organisms genetic characteristics‚ this would also mean that the genetic characteristics that makes up one’s genotype will also determine that individuals phenotype‚ or physical characteristics. Since genetics play a major role in the determination of physical characteristics‚ this would mean that genotype determines phenotype. For instance‚ one simple genetic trait that
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REVISION FOR GENETICS EXAM 1. Make sure you KNOW and UNDERSTAND the following TERMS and DEFINITIONS: -DNA - diploid - genes - haploid - chromosomes - crossing over - sex cells - fertilisation - somatic cells - gamete - autosomes - zygote - sex chromosomes - phenotype - karyotype - genotype - eukaryotic cell division - dominant - mitosis - recessive - meiosis - homozygous - heterozygous - incomplete dominance - codominance - pure bred - hybrid
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