Lipids Biochemistry November 13‚ 2013 Lipids Lipids are families of biomolecules including fats and oils‚ waxes‚ steroids ‚ cholesterol and fat soluble vitamins. All lipids are naturally occurring compounds varying greatly in structure but share the common feature of being soluble in non polar solvents such as chloroform and ether but not in water. Lipids consist mainly of carbon and hydrogen atoms linked by non polar covalent
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TEST | REAGENTS | PROCEDURE | RATIONALE/PRINCIPLE | POSITIVE REACTION | PHENYLHYDRAZINE | phenylhydrazine | | The aldehyde groups of simple carbohydrates will react with phenylhydrazine but instead of yielding typical phenylhydrazones they make what is termed osazones where the OH group immediately adjacent to the keto group is oxidized to a keto group and it too adds phenylhydrazine to form the yellow to pale orange osazones that have definite melting points. So assignment of presumptive identity
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Lipids Lipids don’t dissolve in water contains mostly C‚H‚O (lower ratio of oxygen than do carbohydrates Types: Triglycerides‚ Waxes‚ Phospholipids‚ Sterols Triglycerides: contain glycerol molecule with three fatty acids attached‚ glycerol forms backbone different triglycerides are formed by various fatty acids that attach. Types of triglycerides: Saturated Fat‚ Unsaturated Fat‚ Monounsaturated Fat‚ and Polyunsaturated Fat Saturated Fat: all carbons are saturated with hydrogens there
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foods • Increased sugar intake (Sanders‚ 2014) Bibliography • Lyman‚ E. (2013). Model building lipids [Web] Retrieved from http://youtu.be/4km6BOaj9pg • Sanders‚ J (2014 February 3). Lipids [Webinar]. Retrieved from http://wgu.adobeconnect.com/p46oj5ulh8z/
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Fats‚ waxes‚ monoglycerides‚ and triglycerides are all types of lipids. Triglycerides are a main form of energy for both plants and animals. Triglycerides are broken down into 3 fatty acid chains. Each fatty acid chain is further broken down into multiple groups of Acetyl CoA. Acetyl CoA molecules go through the citric acid cycle and the electron transport chain. 12 ATP are formed from each Acetyl CoA molecule. Carbon chains that are saturated with hydrogen atoms Chains are straight and
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SYLLABUS BCHM 100A: INTRODUCTION TO BIOCHEMISTRY FALL 2012 Instructor: Emily Westover‚ westover@brandeis.edu Kosow 108‚ ext. 6-2304 Office Hours: M 11-1‚ W 1-2‚ or by appointment Assistants: Vy Nguyen‚ vnguyen@brandeis.edu Rick Roy‚ rroy@brandeis.edu Chris Wilson‚ cwilson@brandeis.edu Meetings: Lecture 10:00 – 10:50 am‚ MWH‚ location TBA Recitation 7:30 – 9:20 pm‚ H‚ location TBA Textbook: Lehninger Principles of Biochemistry by Nelson and Cox‚ 4th or 5th Ed. Learning
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Assignment #1 Biochem 305 1) name | 2) name of the coenzyme | 3) RDA mg/day | 4) comm-ercial amt/2capsules | 5)deficiency disease | symptoms of deficiency | 6) problem w/ high amt | B1 Thiamin | Thiamine pyrophosphate (TPP) | 1.1 | 17 mg | Beriberi | impairment of the nerves and heart muscle wasting | anaphylaxis to parenteral thiamin as well as pruritus due to allergic sensitivity to thiamin injection. | B2 Riboflavin | Flavin coenzymes | 1.1 | 17 mg | rare or unobserved | inflammation
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LECTURE NOTES 1: Foundations of Biochemistry - 1 open ended and 5 MC Properties of living organisms - self-replication & self-assembly - sensing and resonding to changes in environment - define function for each component and regulation - Classification of organisms based on where they get their energy Phototrophs (take energy from sun light) Chemotrophs (take energy from food in environment) - organotrophs (bacteria) - not photosynthetic Biological 1) Cellular a. nucleus (eukaryotes)
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Lipids & Fat Casey G. Turner‚ RN Western Governors University Lipids & ATP • Fatty acids are important to energy production. They generate ATP. • This is completed by: 1. Starting with a triglyceride molecule the fatty acid part separates from the glycerol part of the molecule. 2. Once separated‚ the fatty acid chain will break into sections. Each section will be composed of 2 carbon molecules. 3. Each of the carbon pieces will form Acetyl CoA. Each Acetyl CoA enters the Krebs Cycle. 4. It is
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Bioquímica Repaso Examen 1 Chapter 1: Introduction to Biochemistry 1.1 Biochemistry is a Modern Science • By synthesizing urea‚ Friedrich Wöhler showed that compounds found in living organisms could be made in the laboratory from inorganic substances. He used the inorganic compound ammonium cyanate. • Two major breakthroughs in the history of biochemistry are especially notable: o Roles of enzymes as catalysts o Roles of nucleic acids as information carrying molecules.
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