Protein function • Chapter 5.1 • Myoglobin: structure‚ O2-binding • Hemoglobin: structure‚ cooperativity in O2binding‚ Hill constant‚ allosteric interactions‚ Bohr Effect‚ BPG-binding and effect • Abnormal Hemoglobins Functions of Proteins Fibrous proteins: collagen‚ keratin‚ silk - give tensile strength‚ shelter‚ protection Globular proteins: • Storage of ions and molecules – myoglobin‚ ferritin • Transport of ions and molecules – hemoglobin‚ serotonin transporter • Defense against pathogens –
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Male 72 yrs Hb 77g/l (NR 130-180) RBC 2.23 x 10¹²/l (NR 4.5-6.5) MCV 88fl (NR 76-96) WBC 98.2 x 10/l (NR 4-11) Platelets 28 x 10/l (NR 150-400) A) Calculation of PCV (packed cell volume or haematocrit) PCV = RBC (cells/l) x 10¯¹² x MCV (fl) RBC = 2.23 x 10¹²/l MCV = 88fl or 88 x 10/l PCV = 2.23 x 88 x10 PCV = 196.24/1000 PCV = 0.196 (NR 0.4-0.54) B) Calculation of MCH (mean cell volume) MCH = Hb (g/dl) x 10 RBS (cells/l) x 10¯¹² Hb = 77g/l or 7.7g/dl
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February 14 Valuation in a Private Equity Setting Guest Speaker Morris Sandler Introduction to the US LBO Industry Private Equity Information Sources Required Reading Brazos Partners The CoMark LBO Case Due Note on Valuation in Private Equity Settings (HBS 9-297-050) Case 4 Brazos Partners The CoMark LBO The partners of a new midmarket buyout fund are working on a buyout of a closely held modular building company. Although originally structured as a stock deal‚ they have realized that an asset deal
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sickle-cell hemoglobin. In 1956‚ Vernon Ingram developed the technique of fingerprinting peptides in order to pinpoint the difference between HbA and HbS. center6985 Fig: oxyhemoglobin and deoxyhemoglobin center18923000 Ingram’s fingerprints of HbA and HbS revealed that their alpha subunits are identical but that their beta subunits differ by a vari- ation in one tryptic peptide. Sequencing studies eventually
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balanced to have a sustainable deficit. This is echoed by Morgan Stanley Chief Economist Stephen Roach who stated‚ “other countries must learn to grow the old fashioned way – drawing support from their home markets rather than free-riding on the US” (HBS p11). The US has run a current account deficit for over 30 years. This shows that deficits can be sustainable over time. However‚ as of 2005 and earlier‚ the US deficit has spiked to dangerous and unsustainable levels. As of 2008‚ the current account
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Fund‚ Inc (Abridge) Introduction Background of case Study Rick Melnick is an Associate Director of Financial Management at Harvard Business School (HBS). He had decision to make regarding the new funding policy under the management of Student Educational Loan Fund (SELF). SELF was established in 1961 to fund loans to HBS. Traditionally‚ HBS student loans required the borrower to pay semi-annually with variable interest rate policy. Under the new plan‚ the students would receive monthly paid
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[pic] IILM Institute for Higher Education Module Manual: Basics of Economics Academic Year: PGP/ 2012-2014 1. Introduction to the Module and Module Objective Executives‚ consultants‚ investment bankers and many other practitioners make daily economic decisions that explicitly or implicitly follow economic laws. ‘Basics of Economics’ give an introduction to the economics of business decision-making. It is
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Week 1 Deshpande‚ Rohit (2014). Customer Centricity‚ HBS 8171‚ Boston‚ MA: Harvard Business School. 1. a. b. c. d. e. 2. 3. 4. Select a company from the list provided below. Amazon Apple Google Trader Joe’s Starbucks Offer suggestions for how the company might become more customer centric based on the key customer-centric characteristics of successful companies‚ found on page 3 of the reading. Identify company and situational factors that may help get your ideas adopted‚ and factors that may hinder
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ecch the case for learning case collections update 2007 Quarter 4 Visit the case search section of the ecch website at www.ecch.com to identify relevant cases from the ecch collection and view over 31‚000 full text inspection copies. ecch provides a free monthly e-mail update service giving details of new cases from all sources. Visit www.ecch.com to subscribe. Economics‚ Politics and Business Environment 9-407-049 ALLIANZ AG: BECOMING A EUROPEAN COMPANY Lorsch‚ JW; Chernak‚ A Harvard
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This is a preliminary syllabus and is subject to change Syllabus BUFN 771: International Corporate and Project Finance R.H. Smith School of Business University of Maryland‚ College Park Professor Stephen Wallenstein 4458 Van Munching Hall Office hours widely available (call for appointment) 301-405-7177 (office) 919-452-2112 (cell) swallens@rhsmith.umd.edu International Corporate and Project Finance will meet Thursdays from January 26 – March 8‚ 2012 from 6:25-10:00 pm at the
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