Metallobiomolecules METALLOBIOMOLECULES CONTENTS 1. Introduction Metallobiomolecules 2. Classification Metallobiomolecules 2.1. Transport and of to Storage Proteins 2.2. Oxygen binding Today scientists try to explore the chemistry basis behind the biological processes. As a result of this‚ new areas have evolved such as bioinorganic chemistry and bioorganic chemistry. In this section we will talk about an important concept in bioinorganic chemistry called “Metallobiomolecules”. Metallobiomolecules
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Although vaccination has proved to be an effective measure in preventing disease‚ controversies remain over whether the risks of side effects of vaccinations outweigh the risk of contracting the disease. Vaccination is the process when pathogenic cells are injected into the cells of a healthy person so that the body develops immunity through antibodies to that virus or bacterium. The U.S Center for Disease Control and Prevention recommends that children get 16 vaccines including Diphtheria‚ hepatitis
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dissolved O2 (1.5%) b. 98.5 % – bound to Hemoglobin (iron in Heme group) 2. Hemoglobin saturation a. 4 O2 = 100% b. 2 O2 = 50% c. Hb binds O2 reversibly B. Oxygen-Hemoglobin dissociation curve 1. Relates saturation of Hb with pO2 increase Hb saturation ( ↑ affinity)2. increase pO2 —— a. Hb stores O2 decrease Hb saturation (↓affinity)3. decrease pO2 —– a. Hb releases O2 4. Normal tissue 75% (pO2 = 40 mmHg)a. 97% (pO2 = 95 mmHg) —– b. Venous blood has large O2 reserve 5. Active tissue
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flow index ASTM D1238 200°C‚ 5KG 1.8 hardness ASTM D785 1/2” 116 Specific gravity ASTM D792 23°C 1.05 Vicat softening temp ASTM D1525 1/8”‚ 50°C/hr 105(221) Annealed unannealed ASTM D648 1/4”‚ 120°C/hr 99(210) 88(190) flammability UL94 - 1/16”HB ABS 757 Processing parameters A: dry: 80-85°C‚ 2-4 hours It will be affected by following factors: 1. Humidity 2. Recycle material property 3. Storage condition B: barrel temperature Highest temperature: 230 Lowest temperature; 190 C: mould temperature
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nitrogens from tetrapyrrole ring system ii. 5th bond - Helix F binds to Fe at terminal Histidine th * 5 bond = helix F8‚ residue 93 in Mb‚ molecule (His F8)* = proximal histidine residue 92 in the β-chain of Hb and iii. 6th bond – deoxygenated: empty‚ histidine residue from residue 87 in α-chain of Hb th helix E** hovers; oxygenated: oxygen bonds here ** 6 bond = helix E7‚ His 64 for Mb‚ His 63 in b-chain and 58 in a-chain c. Oxygen binds to Fe at 120° angle easily removed II. MYOGLOBIN A. Physico-chemical
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or Adult Nurse Practitioner‚ orders the following labs: urinalysis‚ hemoglobin A1C‚ fasting complete metabolic panel (CMP)‚ CBC‚ fasting lipid profile‚ and glomerular filtration rate (GFR). The lab values are as follows: fasting glucose 184 mg/dl‚ Hb A1C 10.4‚ UA +glucose‚ -ketones‚ cholesterol 256 mg/dl‚ triglycerides 346 mg/dl‚ LDL 155 mg/dl‚ HDL 32 mg/dl‚ ratio 8.0. A subsequent fasting glucose is also elevated and Y.L is diagnosed with type 2 diabetes mellitus. After
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PACE UNIVERSITY Managing Innovation MBA-678 - Fall 2014 Section(s) CRN 71670 (lecture)‚ - Tuesdays 5:40-8:30PM Classroom(s): PNY W-522 Professor: John C. Byrne‚ Ph.D. Office: W491 (PNY). Pace Phone: 212-618-6581 Office Hours: Home Phone: 201-722-1459 – BEST ! Tue.: – 02:30-5:00pm – PNY e-mail: jbyrne@pace.edu – BEST ! Wed: – 02:30-5:00pm – GC Due to having to visit multiple campuses and the usual sundry meetings‚ etc.‚ it would be best to send me a note with a request
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Fracking Permitting Guidance as proposed by EPA’s The various rules and legislations that have been adopted by the states such as the Wyoming Oil and Gas Regulation‚ Arkansas Oil & Gas Commission Rule B-19‚ Michigan DEQ Permitting Instructions‚ Texas HB 3328 (June 2011) and Texas Railroad Commission Proposed
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civilization into confusion and chaos. He must always be working and alert among the "savages" who know only the law of "club and fang." Attack is a constant threat. The good-natured Curly is killed simply for trying to make friendly advances towards a husky dog only have her size. The dog takes her down with efficient‚ quick technique. Once it is certain that Curly will not rise again‚ the rest of the dogs in the camp attack and kill her. Spitz‚ the lead dog of Buck’s team‚ laughs. Buck hates him bitterly
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HEENT: Head‚ NCAT‚ MMM‚ EOMI‚ PERRLA‚ b/l TM intact & Normocephalic atraumatic‚ mucous membranes moist‚ eyes‚ ears‚ nose‚ throat reactive to light‚ b/l sclera anicteric‚ Ø extraocular muscles intact‚ pupils equally round and reactive conjunctival injection to light and accommodation bilaterally‚ bilateral tympanic
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