Protein function • Chapter 5.1 • Myoglobin: structure‚ O2-binding • Hemoglobin: structure‚ cooperativity in O2binding‚ Hill constant‚ allosteric interactions‚ Bohr Effect‚ BPG-binding and effect • Abnormal Hemoglobins Functions of Proteins Fibrous proteins: collagen‚ keratin‚ silk - give tensile strength‚ shelter‚ protection Globular proteins: • Storage of ions and molecules – myoglobin‚ ferritin • Transport of ions and molecules – hemoglobin‚ serotonin transporter • Defense against pathogens –
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Buck decided to never be put on his back in a fight or else the surrounding dogs will attack and finish him off. (quote) The other huskies ravaged Curly because she was too affectionate for the environment making her unfit. (((((Buck learned to be quick and steal‚ stay warm in the snow at night‚ ))))))))))))))))) Sol-leks’s blind side was an important lesson to Buck when he was slashed
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Male 72 yrs Hb 77g/l (NR 130-180) RBC 2.23 x 10¹²/l (NR 4.5-6.5) MCV 88fl (NR 76-96) WBC 98.2 x 10/l (NR 4-11) Platelets 28 x 10/l (NR 150-400) A) Calculation of PCV (packed cell volume or haematocrit) PCV = RBC (cells/l) x 10¯¹² x MCV (fl) RBC = 2.23 x 10¹²/l MCV = 88fl or 88 x 10/l PCV = 2.23 x 88 x10 PCV = 196.24/1000 PCV = 0.196 (NR 0.4-0.54) B) Calculation of MCH (mean cell volume) MCH = Hb (g/dl) x 10 RBS (cells/l) x 10¯¹² Hb = 77g/l or 7.7g/dl
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February 14 Valuation in a Private Equity Setting Guest Speaker Morris Sandler Introduction to the US LBO Industry Private Equity Information Sources Required Reading Brazos Partners The CoMark LBO Case Due Note on Valuation in Private Equity Settings (HBS 9-297-050) Case 4 Brazos Partners The CoMark LBO The partners of a new midmarket buyout fund are working on a buyout of a closely held modular building company. Although originally structured as a stock deal‚ they have realized that an asset deal
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championships. Still‚ the tickets to see this legendary team play cost less than tickets to see a pretty good‚ but not iconic‚ UCONN Men’s Basketball team play. The team has dominated so much over the past couple of years‚ that you know the UCONN women huskies will win
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sickle-cell hemoglobin. In 1956‚ Vernon Ingram developed the technique of fingerprinting peptides in order to pinpoint the difference between HbA and HbS. center6985 Fig: oxyhemoglobin and deoxyhemoglobin center18923000 Ingram’s fingerprints of HbA and HbS revealed that their alpha subunits are identical but that their beta subunits differ by a vari- ation in one tryptic peptide. Sequencing studies eventually
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balanced to have a sustainable deficit. This is echoed by Morgan Stanley Chief Economist Stephen Roach who stated‚ “other countries must learn to grow the old fashioned way – drawing support from their home markets rather than free-riding on the US” (HBS p11). The US has run a current account deficit for over 30 years. This shows that deficits can be sustainable over time. However‚ as of 2005 and earlier‚ the US deficit has spiked to dangerous and unsustainable levels. As of 2008‚ the current account
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Fund‚ Inc (Abridge) Introduction Background of case Study Rick Melnick is an Associate Director of Financial Management at Harvard Business School (HBS). He had decision to make regarding the new funding policy under the management of Student Educational Loan Fund (SELF). SELF was established in 1961 to fund loans to HBS. Traditionally‚ HBS student loans required the borrower to pay semi-annually with variable interest rate policy. Under the new plan‚ the students would receive monthly paid
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The man is traveling alone alongside his native husky‚ who also does not like the idea of traveling in such cold weather. It is below fifty degrees and there is not one soul out on the road. The man has nine hours of hiking ahead of him and the temperature is only getting colder. He did
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club was a valuable experience‚ for he learned that there was no way to beat a man with a club. 6. Buck’s impression of Francois and Perrault were fair‚ wise‚ and respectable men. Chapter 2 1. Curly naively approached and acted friendly to a husky. The husky ripped her face open‚ and as Curly fell to the ground‚ all the other wild dogs closed in and killed her. Buck was hated Spitz for laughing at Curly’s tragic death. 2. Buck slept in a warm hole he dug in the snow. 3. Buck ate fast because of
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