H2O‚ and most of it is carried by Hb in the RBC’s. The interaction of iron ions with O2 binds O2 to the Hb‚ forming ‘oxyhaemoglobin’‚ (HbO2). This happens when the pressure (concentration) of O2 is very high for example‚ in the lungs. Each Hb can bind four O2 (one molecule per haem). The reverse occurs in the body cells‚ where O2 pressure (concentration) is low: increase in oxygen concentration Hb + O2
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experienced develop in their work. Coaching refers to a more systematic process where one person takes another through an experiential learning cycle‚ with the intention of unlocking the individual’s potential to maximize their own performance.” (Winfield‚ 2011) Who benefits from coaching and mentoring? How do they benefit from coaching and mentoring? How can the school make coaching and mentoring more effective? How can you and your partners come together to achieve your goal? How can we use this
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Review Sheet Results (1) 1. List the hematocrits for the healthy male (sample 1) and female (sample 2) living in Boston (at sea level) and indicate whether they are normal or whether they indicate anemia or polycythemia. 1. The hematocrit value for the healthy male: 48 2. The hematocrit value for the healthy female: 44 Both values are normal because they are between the normal ranges: for males between 42-52% and for females between 42-47%. 2. Describe the difference between the hematocrits
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1. The MGI team process and root causes. The MGI team process seems ineffective because the team generated several conflicts and was unorganized because of the different perspectives‚ specifically those between the Russians and the HBS students. In addition‚ because each member had an ambiguous role‚ they needed to spend unproductive times on the meetings. According to Robbins and Judge (2012‚ p. 122)‚ by structuring teams‚ they can compete with each other more effectively and efficiently. Nevertheless
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Protein function • Chapter 5.1 • Myoglobin: structure‚ O2-binding • Hemoglobin: structure‚ cooperativity in O2binding‚ Hill constant‚ allosteric interactions‚ Bohr Effect‚ BPG-binding and effect • Abnormal Hemoglobins Functions of Proteins Fibrous proteins: collagen‚ keratin‚ silk - give tensile strength‚ shelter‚ protection Globular proteins: • Storage of ions and molecules – myoglobin‚ ferritin • Transport of ions and molecules – hemoglobin‚ serotonin transporter • Defense against pathogens –
Free Hemoglobin Protein
Male 72 yrs Hb 77g/l (NR 130-180) RBC 2.23 x 10¹²/l (NR 4.5-6.5) MCV 88fl (NR 76-96) WBC 98.2 x 10/l (NR 4-11) Platelets 28 x 10/l (NR 150-400) A) Calculation of PCV (packed cell volume or haematocrit) PCV = RBC (cells/l) x 10¯¹² x MCV (fl) RBC = 2.23 x 10¹²/l MCV = 88fl or 88 x 10/l PCV = 2.23 x 88 x10 PCV = 196.24/1000 PCV = 0.196 (NR 0.4-0.54) B) Calculation of MCH (mean cell volume) MCH = Hb (g/dl) x 10 RBS (cells/l) x 10¯¹² Hb = 77g/l or 7.7g/dl
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February 14 Valuation in a Private Equity Setting Guest Speaker Morris Sandler Introduction to the US LBO Industry Private Equity Information Sources Required Reading Brazos Partners The CoMark LBO Case Due Note on Valuation in Private Equity Settings (HBS 9-297-050) Case 4 Brazos Partners The CoMark LBO The partners of a new midmarket buyout fund are working on a buyout of a closely held modular building company. Although originally structured as a stock deal‚ they have realized that an asset deal
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sickle-cell hemoglobin. In 1956‚ Vernon Ingram developed the technique of fingerprinting peptides in order to pinpoint the difference between HbA and HbS. center6985 Fig: oxyhemoglobin and deoxyhemoglobin center18923000 Ingram’s fingerprints of HbA and HbS revealed that their alpha subunits are identical but that their beta subunits differ by a vari- ation in one tryptic peptide. Sequencing studies eventually
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balanced to have a sustainable deficit. This is echoed by Morgan Stanley Chief Economist Stephen Roach who stated‚ “other countries must learn to grow the old fashioned way – drawing support from their home markets rather than free-riding on the US” (HBS p11). The US has run a current account deficit for over 30 years. This shows that deficits can be sustainable over time. However‚ as of 2005 and earlier‚ the US deficit has spiked to dangerous and unsustainable levels. As of 2008‚ the current account
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Fund‚ Inc (Abridge) Introduction Background of case Study Rick Melnick is an Associate Director of Financial Management at Harvard Business School (HBS). He had decision to make regarding the new funding policy under the management of Student Educational Loan Fund (SELF). SELF was established in 1961 to fund loans to HBS. Traditionally‚ HBS student loans required the borrower to pay semi-annually with variable interest rate policy. Under the new plan‚ the students would receive monthly paid
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