pharmacology of the cephalosporins is similar to that of the penicillins‚ excretion being principally renal. The principal side-effect of the cephalosporins is hypersensitivity and about 0.5–6.5% of penicillin-sensitive patients will also be allergic to the cephalosporins. If a cephalosporin is essential in patients with a history of immediate hypersensitivity to penicillin‚ because a suitable alternative antibacterial is not available‚ then cefixime‚ cefotaxime‚ ceftazidime‚ ceftriaxone‚ or cefuroxime can
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Phase 0 1 2 3 Also known as Microdosing Human Pharmacology Therapeutic Exploratory 2a 2b Therapeutic Confirmatory 3a 3b Objective PK /PD /Other Enable go/no-go decisions to be based on relevant human models instead of relying on sometimes inconsistent animal data. Safety & tolerability-Maximum tolerated dose PK PD safe dose range PK Safety Efficacy PK Safety Efficacy Safety Special studies (Qol‚ DDI‚ FDI) Sub group Efficacy Safety Special studies
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Faculty of Medicine MAHSA UNIVERSITY STUDY GUIDE Block: Genetics‚ Immunology & Molecular Medicine (GIM) Session: 2013/2014 Semester 1 (Year 1) MBBS PROGRAM Block Coordinator: Dr Selvi Palasubramaniam CONTENTS 1. Teaching Staff & Contacts 2 2. Academic calendars MBBS Session 2013 / 2014 3 3
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GRADED ASSIGNMENTS Data Assessment and Care Plan Nursing Care Plan Instructions: Prepare a plan of care for your patient. The plan of care must include a complete DATA ASSESSMENT with all pertinent data and interpretation of data completed. Based on the data‚ formulate an individualized care plan using (1) priority NANDA diagnosis and (2) secondary NANDA diagnoses. Each diagnosis requires at least (5) interventions‚ (5) rationales and (5) outcomes
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OUTLINE OF TOPICS IMMUNOLOGY AND SEROLOGY Dec 14‚ 2014 8:00 am – 12:00 nn Part 1: IMMUNOLOGY UNIT 1: INTRODUCTION 1. Historical Development 2. Definition of Terms UNIT II: IMMUNITY 1. Natural/Innate Immunity First line of Defense Anatomical/ Physical Barriers of Infections Second Line of Defense Physiological Barriers Biochemical Factors Cellular Factors Phagocytosis Third Line of Defense Immune response 2. Acquired/Adaptive Immunity Active Acquired Immunity Passive Acquired Immunity Humoral Immunity
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irrational‚ disabling fear as a mental disorder (e.g. agoraphobia)‚ in chemistry to describe chemical aversions (e.g. hydrophobic)‚ in biology to describe organisms that dislike certain conditions (e.g. acidophobia)‚ and in medicine to describe hypersensitivity to a stimulus‚ usually sensory (e.g. photophobia). In common usage they also form words that describe dislike or hatred of a particular thing or subject. The suffix is antonymic to -phil-. For more information on the psychiatric side‚ including
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GASTRO ESOPHAGEAL REFLUX DISEASE (GERD) General Description of GERD It is one of the most common diseases‚ greatly affecting health care and contributing to the expenditure in the United States of nearly 12 billion dollars per year for antacid medications. GERD affects nearly equal proportions of men and women‚ but a male predominance occurs in esophagitis and Barrett’s esophagus. Increasing age is an important factor in the prevalence of GERD complications‚ probably the result of cumulative
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INTRODUCTION : Imipramine belongs to a group of medicines called tricyclic antidepressants. It affects chemicals in the brain that may become unbalanced. It is generally used to treat symptoms of depression. However‚ it is also used to treat a completely unrelated condition in children‚ known as nocturnal enuresis (night-time bedwetting). TRADE NAMES : TofranilAntidepAntipresMicrodepPraminGENERIC NAME : Imipramine hydrochloride ACTION : Antidepressant AVAILABLE FORMS : Tablets (imipramine
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Generic Name: meperidineBrand Name(s): Demerol | Pregnancy Category: C | Route of Administration: IM‚ SUBCUT | Drug Category: opioids analgesic | Indication: labor analgesia | Normal Dosage:Labor analgesia Adult: 50-100 mg given when contractions regularly spaced repeat q1-3h prn | Side Effects:CNS: drowsiness‚ dizziness‚ confusion‚ HA‚ sedation‚ euphoria‚ increased intracranial pressure‚ seizures‚ respiratory depression‚ anaphylaxis | Nursing Considerations/Teachings/Interventions: Nursing
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CBC w/ Differential CBC w/ Differential Fight infection Attack foreign material 4500-17000 Lifespan= hours-days Fight infection Attack foreign material 4500-17000 Lifespan= hours-days WBC Elevated: Infection‚ tissue necrosis‚ bone marrow malignancies‚ inflammation Decreased: infection‚ medications that suppress or weaken the immune system or bone marrow WBC Elevated: Infection‚ tissue necrosis‚ bone marrow malignancies‚ inflammation Decreased: infection‚ medications that suppress
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