Activity: Action Potentials Name: Caitlin Magnacca Instructor: Date: 03.19.2015 Predictions Exceeding threshold depolarization at the trigger zone______the likelihood of generation of an action potential. increases Action potential amplitude decreases with distance Increasing frequency of stimulation to the trigger zone increases number of action potentials Materials and Methods Experiment 1: Effect of Stimulus Strength on Action Potential Generation Dependent Variable membrane potential Independent
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Angiotensin-II Receptor Blockers (ARBs): ARBs are a class of drugs that halt the action of Angiotensin-II by blocking the binding between Angiotensin-II and Angiotensin-II receptors. This leads to reduced blood pressure as the blood vessels get dilated. This reduced blood pressure helps to ease heart failure as it now becomes easier for the heart to pump this blood. Commonly used ARBs are Irbesartan‚ candesartan‚ Losartan‚ Olmesartan‚ Telmisartan‚ valsartan‚ and azilsartan. Mechanism Angiotensin-II
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MINIREVIEW Folate Receptor-Mediated Drug Targeting: From Therapeutics to Diagnostics ANDREW R. HILGENBRINK‚ PHILIP S. LOW Department of Chemistry‚ Purdue University‚ West Lafayette‚ Indiana 47907 Received 25 May 2005; accepted 27 June 2005 Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/jps.20457 ABSTRACT: Folate targeted drug delivery has emerged as an alternative therapy for the treatment and imaging of many cancers and inflammatory diseases. Due to its
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Overview “muscarinic receptor agonists” cholinergic agonists are drugs that act on acetylcholine receptors‚ thus causing excitation of the parasympathetic autonomic nervous system there are 2 types of acetylcholine receptors 1) NICOTINIC RECEPTORS - are receptor-mediated ion channels - 3 types RECEPTOR TYPE MUSCLE TYPE GANGLION TYPE LOCATION - neuromuscular junction - sympathetic autonomic ganglia - parasympathetic autonomic ganglia - CNS CNS TYPE - agonists of nicotinic receptors are discussed
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EVALUATION OF EFFECTS OF OVARIECTOMY AND TREATMENT WITH ESTROGEN-REPLACEMENT THERAPY OR SELECTIVE ESTROGEN RECEPTOR MODULATORS (SERM) ON VOIDING FUNCTION AND P2X RECEPTOR EXPRESSION IN THE FEMALE RAT TABLE OF CONTENTS Abbreviations Page 6 Abstract Page 6 Study 1 Page 10 Introduction Page 10 Menopause and the overactive bladder Page 10 Estrogens for the treatment of OAB in post menopausal women Page 12 SERM and tamoxifen Page 15
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9‚ 2013 Music’s potential as a positive stimulus for the brain Music’s potential as a positive stimulus for the brain Word Count: 1190 Ioannis
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1. What is modality? Modality is concerned with expressing opinions and attitudes. Modality in general is defined similarly in many reference books. For example Quirk‚ Greenbaum‚ Leech and Svartvik (1985) claim‚ that “at its most general‚ modality may be defined as the manner in which the meaning of a clause is qualified so as to reflect the speaker’s judgment of the likelihood of the proposition it expresses being true” (p. 219). However‚ the authors deal with the term modality mainly in connection
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Esthesioneuroblastoma is also referred to as olfactory neuroblastoma. This inherited gene passes on to the next generation and in some instances more than one tumor develops. As an autosomal recessive disorder‚ the offspring inherits two mutated genes and two normal genes– one from each parent. In some cases‚ the parents show no signs of the disorder verifying the normal genes as dominate. Even though this is a rare condition‚ more prevalent in adults‚ heredity increases the chances of developing
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Prostaglandin E2 EP3 receptor regulates cyclooxygenase-2 expression in the kidney Carlos P. Vio‚ Mariana Quiroz-Munoz‚ Catherina A. Cuevas‚ Carlos Cespedes and Nicholas R. Ferreri Am J Physiol Renal Physiol 303:F449-F457‚ 2012. First published 23 May 2012; doi: 10.1152/ajprenal.00634.2011 You might find this additional info useful... This article cites 55 articles‚ 29 of which you can access for free at: http://ajprenal.physiology.org/content/303/3/F449.full#ref-list-1 This article has been cited
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400 distinct odorant receptors Special proteins detecting different odors Complex olfactory system: Odorant receptors: identify different aromatic compounds and pheromones‚ and most dominant in ants Gustatory receptors: distinguish between different tastes and react to some pheromones Ionotropic glutamate receptors: narrowly tune to various poisonous and toxic compounds Two species will not have the same number of receptors‚ because of the difference of two species in terms of lifestyle Differences
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