Outline of Lecture Topics: fL t T i 1. Immune Responses 1 Immune Responses 2. Classes of Immunosuppressive Drugs Bertram G Katzung‚ 11th Edition. Chapter 55‚ pp 963-986. Immunosuppressive Immunosuppressive Drugs drugs g 1. IMMUNE RESPONSES A. Normal Immune Responses Protect host from infections‚ pathogens‚ and to eliminate disease. Protection from infection and disease is provided by the collaborative efforts of the innate and adaptive disease is provided by the collaborative efforts of the innate and adaptive Immunity
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ntthoai@hcmiu.edu.vn NTTH-HCMIU-IMMUN-2013 Introduction to IMMUNOLOGY- An X soup • What is Immunology? What is Immune System (IS)? • History of Immunology • Cells and Soluble Mediators of IS= ? • Immune Response- Pathogens (Ags): Innate and Adaptive Immunity- Collaboration NTTH-HCMIU-IMMUN-2013 Introduction to IMMUNOLOGY What is Immunology? What is Immune System (IS)? Immunology is the study of our protection from foreign macromolecules or invading organisms and our responses to
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Mindanao Medical Foundation College P. Villanueva St.‚ Davao City Course Syllabus Course Title: Immunology and Serology Course Description: Immunology is the study of the human body’s immune response to foreign antigens and disease. Serology is the study of constituents in serum that can be used for detection of disease and monitoring of therapy through serological laboratory testing. Course Credits: 4 Units Vision Statement: Mindanao Medical Foundation College is a private‚
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because the bubonic plague is a very serious and deadly disease. Extending our knowledge of it will only benefit us. If I were to ask a question pertaining to Y. pestis it would be if subjecting a subject to a weaker strain of the virus would create an immune defense against it and if it would be able to get passed down through genetics. I would hypothesis that given the advances in medicine and technology it would be possible. My experiment would be conducted in a small secluded part of the world using
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However‚ C. trachomatis is capable of evading the host innate and adaptive immune response using many different mechanisms while resides in the genital epithelial cell [42–46]. Studies using a prospective cohort of women in high risk for chlamydia infection show that efficient immune response that correlate with protection against infection or reduced risk for reinfection‚ consist of the production of IFN-γ by peripheral-blood
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important role in explaining to patients the novel risk assessment and the treatment strategies and ongoing clinical trials they will go through (Heeger P.S. and Dinavahi MD.R‚ 2012). Human immune system is divided into innate and adaptive. Innate immunity is rapid but with no memory and little specificity. Innate immunity surrounds cellular components (eg. dentritic cells- DCs and natural killer cells -NKCs) and molecular components (eg. toll-like receptors- TLRs). Microbial products or endogenous
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Chapter 21 The Immune System: Innate and Adaptive Body Defenses Innate and Adaptive Defenses (Fig. 21.1‚ pg. 767) Body Defenses against Infection (Fig. 21.1‚ pg. 767) * Immunity * Resistance to disease * Pathogen * disease causing agent * bacteria‚ viruses‚ etc * Innate (nonspecific) Defenses * responds quickly * general defenses * protects against many pathogens * First line of defense * skin and mucosae prevent entry of microorganisms
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Innate Targeting of Pathogens Pathogen Examples Facts Pattern recognition alerted by Viruses flu‚ small pox‚ HIV‚ polio‚ Ebola‚ rhinovirus‚ hepatitis‚ measles Can only reproduce inside cells Foreign nucleic acids (double stranded RNA‚ single stranded DNA‚ foreign methylation patterns)‚ reduced antigen presentation by infected cells So viruses are usually recognized by something unusual in their nucleic acids.(Double RNA‚ normally‚ RNA is a single strain) Bacteria
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also known as NK cells‚ are primarily a supportive type of cell which aids in protecting you from distinct infections and even cancer‚ as these cells target tumor cells.1 The natural killer cell plays a severe role in administering the innate and adaptive immune response to pathogens‚ injury‚ and stress. Natural killer cells acquired their name from the fact that they are propagated naturally by the body and their sole purpose is to search for and suppress destructive cells. When a destructive cell
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Immunity Objectives 1) Describe the cell functions of the Immune System: Lymphocytes- small white blood cells that are responsible for much of the work of the immune system. Three types: Natural Killer Cells-NK cells provide rapid responses to virally infected cells and respond to tumor formation. NK cells are unique bc they have the ability to recognize stressed cells in the absence of antibodies and MHC‚ allowing for a much faster immune reaction. Trigger phagocytes to the site. Doesn’t recognize
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