Grignard Reaction: Synthesis of Triphenylmethanol Hai Liu TA: Ara Austin Mondays: 11:30-2:20 Abstract: In this experiment‚ phenylmagnesium bromide‚ a Grignard reagent was synthesized from bromobenzene and magnesium strips in a diethyl ether solvent. The Grignard reagent was then converted to triphenylmethanol‚ a tertiary alcohol with HCl. The reaction for phenylmagnesium bromide was: The reaction for Grignard to triphenylmethanol was: In the formation of the Grignard reagent
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Phenylmagnesium bromide was then transformed into a tertiary alcohol called triphenylmethanol‚ through addition of another compound called benzophenone‚ as well as additional ether. The end product of triphenylmethanol was analyzed via NMR and IR. Figure 1: Preparation of the Grignard agent by combining bromobenzene with magnesium and ether to produce phenylmagnesium bromide. Figure 2: Production of triphenylmethanol by combining benzophenone and the Grignard reagent. Introduction Grignard reagents
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in the formation of triphenylmethanol from phenyl magnesium bromide and benzophenone. A recrystallization was performed to purify the Grignard product by dissolving the product in methanol. From here‚ a melting point range of 147.0 °C to 150.8 °C was obtained. The purified product yielded an IR spectrum with major peaks of 3471.82 cm-1‚ 3060.90 cm-1‚ 1597.38 cm-1‚ and 1489.64 cm-1‚ which helped to testify whether the identity of the product matched the expected triphenylmethanol. The identity of the
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reaction Abstract: In this laboratory‚ triphenylmethanol was synthesised from reacting benzophenone and bromobenzene using Grignard reaction. As the reaction was to set up to produce a Grignard reagent and then recrystallize it to obtain pure sample. The percentage yield obtained was 55% and its melting point was 161 co which is within the literature value 160-163 co. In addition to that the IR spectroscopy confirmed the molecule structure to be triphenylmethanol. Introduction: The Grignard reagents
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Procedure: The experimental laboratory procedures were divided into two categories. First the formation of phenylmagnesium bromide‚ and second the reaction of the phenylmagnesium bromide with the carbonyl compound. However‚ before any of this could be done‚ the refluxing apparatus for the Grignard reaction was to be flame dried until no moisture remained inside because any water would cause the reagent to decompose and an alkane to form. The reaction would subsequently fail. Drierite was placed
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Grignard Synthesis of Tirphenylmethanol David Szuminsky Organic Chemistry Lab II Shaopeng Zhang Monday 1PM 2/10/14 & 2/24/14 - Abstract A sample of triphenylmethanol was prepared using Grignard synthesis techniques. Reflux was used in order to speed up the reaction and the final product was purified using recrystallization methods. The percent recovery and percent yield were 80.46% and 47.526%‚ respectively. A melting point range of 85-87oC was obtained from
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The Grignard Synthesis of Triphenylmethanol Abstract: Grignard synthesis of triphenylmethanol was achieved by use of the Grignard reagent phenyl magesium brominde. The organometallic grignard reagent was synthesized by use of a reflux apparatus recrystallization techniques. Once synthesized it was used in a Grignard reaction that involved nucleophilic addition to a carbonyl in order to make triphenylmethanol. The final product was solidified and recrystallized and spectral data was
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Mechanism for coupling reactions In this experiment‚ a Grignard reagent was prepared and reacted with benzophenone to synthesize triphenylmethanol‚ a tertiary alcohol (Figure 4). The Grignard reagent was prepared with dry magnesium turnings‚ bromobenzene and anhydrous ether. To isolate the alcohol‚ dilute acid was used to convert the magnesium salt to free alcohol and the mixture was washed
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Name Lab Section GTA Station 1. Grignard Reaction Post-lab report Fill out the appropriate sections below. Show all work. Your calculated answers need to match the answers in the table. Also‚ attach the benzophenone and product spectra. Indicate appropriate stretches including differences in both spectra. Results | | Amounts and units | |Initial
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| Reactions of Grignard Reagents with Carbonyls | | | Tuesday 1:30 | 2/28/2012 | | Introduction This experiment explores the reactivity pattern for the addition of Grignard reagents to three different carbonyl groups: a ketone‚ an ester‚ and a carbonate. Grignard reagents are organometallic compounds that have a carbon-metal bond‚ such as carbon-magnesium. Grignard reagents are formed from the reaction of an alkyl‚ cycloalkyl‚ or aryl halide and magnesium metal in dry ether
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