Text Introduction In 2001‚ Sony Computer Entertainment published a game developed by Naughty Dog called “Jak and Daxter: Precursor’s Legacy”. This is the first game of the Jak trilogy and it is a challenging open-world platformer developed with the same cartoon-like style of Spyro and Crash Bandicoot. It is currently one of Play Station two’s greatest hits and it has been remastered for PS3 and PS4. Text Synopsis Ignoring the advice of the sage‚ our heroes journeyed to Misty Island in search of
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“Kevin‚” shouted his mom‚ “time for breakfast!” “Coming‚” said Kevin. He got out of bed and looked at his pet weasel‚ Daxter. He had named him after a character in the video game‚ “Jak and Daxter.” Daxter looked hungry. “I’ll bring you some bacon from downstairs‚” said Kevin. Kevin walked down the stairs. “There you are‚” said his dad‚ “how’s your hand?” “Still glowing‚” replied Kevin. Kevin’s right hand had been glowing ever since he was born. The doctors were still trying to figure out why. Kevin
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Polonius is much like that of Simon. Just like Simon‚ who finds out what the beast really is‚ Polonius listens in on Hamlet talking to his mother and figures out the truth about why Hamlet is really upset. Because he discovered this very much needed piece of information he is tragically killed by Hamlet. Just like Simon is killed by the group of boys before he even gets the chance to tell anyone about what he had discovered. Between the books of Shakespeare’s play Hamlet and Golding’s novel Lord
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defendant’s right to confront the witness against him. Since Ms. Aran elected not to testify at trial‚ all statements she made (excluding the excited utterance exception) should not have been used at trial. The testimony from the 911 operator‚ Mr. Daxter‚ and Ms. Esteed‚ however‚ were rightfully admitted because they were either not hearsay or hearsay exceptions under Rule 803 of the Federal Rules of Evidence. Fed. R. Evid.
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Hello‚ I am Daniel. Welcome to my semiotic analysis of the Opening Credits of “The Last of Us”. First‚ let’s introduce some terms. Semiotics is the study of signs. As defied by Chandler‚ *SHOW IMAGE* “A sign is a meaningful unit which is interpreted as ‘standing for’ something other than itself.” “…the signifier is the form which a sign takes… something which can be seen‚ heard‚ felt‚ smelt or tasted” and the “…signified is the mental concept represented by the signifier”. (Chandler‚ 2013). Denotation
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CHEMISTRY LEVEL 3C (CHM 315109) CORROSION THEORY SUMMARY & REVISION QUESTIONS (CRITERION 5) Tasmanian TCE Chemistry Revision Guides by Jak Denny are licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License INDEX: PAGES • INTRODUCTION • EFFECTS OF CORROSION • ELECTROCHEMICAL EFFECTS • FACTORS AFFECTING CORROSION • THE RUSTING OF IRON • IDENTIFYING ANODES & CATHODES • DIAGRAMMATIC SUMMARY • DIFFERENTIAL AERATION • DIFFERENT METALS IN CONTACT • CORROSION
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I n t r o d u c t i o n t o M a r k e t i n g B u s i n e s s 1 2 0 A marketing plan focusing on Sony’s Playstation 3. Marketing Plan: Sony Playstation 3 2 Executive Summary This marketing plan is looking at Sony’s Playstation 3 (PS3). This powerful piece of hardware is the cutting edge of gaming entertainment. The PS3 has been out for a little over a year‚ and in that time‚ it has proved to be a hardcore gamers dream. Sony got into the console gaming market in late 1994. The concept
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bond with the bond length of 1.8 Å. In addition to the hydrogen bonds‚ hydrophobic interaction was exhibited between phenyl ring of the 3a and Leu-855‚ Ala-880‚ Val-911‚ Leu-932‚ Leu-983 and Gly-993 amino acids. Binding interaction of the 3a with the JAK-2 is receptor shown in Figure 11B1 and 11B2. Compound 3a showed the binding energy value of -6.04 kcal/mol with the docked Bcl-2 receptor and it was interacted with the 14 active sites of amino acids namely Phe-63‚ Tyr-67‚ Asp-70‚ Phe-71‚ Met-74‚ Val-92
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Drug Approval in 2013 • PERFORMANCE OF IPOS: 2013 • DRUG LAUNCHES: 2014/15 • Unmet Need of Innovators - Launched and Pipeline Unpartnered Compounds • Competition can reduce the life span of innovative patented drugs- Competitive landscape of PI3K‚ Jak and BTK inhibitors in clinical development • Resisting resistance – Global threat and Action taken • Oral vs. Injectables – Oral drugs for MS‚ RA and Psoriasis • Targeting Unmet Need on Hematological Malignancies- RRMM‚ RRMDS In-depth Company
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Active compounds were profiled further for their ability to inhibit the activation and differentiation of human monocytes using disease-related stimuli. Inhibitors targeting NF-κB or Janus Kinase/Signal Transducer and Activator of Transcription (JAK/STAT) signaling emerged as “dissociated inhibitors” because they did not modulate IFN-α anti-viral effects against HSV-1 but potently inhibited other immune-related functions. This work describes a novel strategy to identify small molecule inhibitors
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