about one percent of her T cells incorporated the virus into their DNA. In another case‚ an 18-year-old Arizona man with a rare metabolic disease participated in a controversial experiment which marked the first death attributed to gene therapy. Jesse Gelsinger‚ a high school graduate who episodically suffered from a serious genetic disorder that often leads
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Gene therapy for disease (: Most of us‚ don’t think there are many cures for a lot of diseases and types of medical treatment we didn’t think was possible basically that is what gene therapy is in a nut shell; with its potential to eliminate or prevent diseases such as cystic fibrosis and hemophilia. It could even find a cure for AIDS‚ cancer‚ and heart disease. Gene therapy could be a medical life saver. What is Gene therapy for disease? Genes are what make you ‚ you. We get half of our genes
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“Human genetic engineering is the alteration of an individual’s genotype with the aim of choosing the phenotype of a newborn or changing the existing phenotype of a child or adult. It holds the promise of curing genetic diseases like cystic fibrosis‚ and increasing the immunity of people to viruses. It is speculated that genetic engineering could be used to change physical appearance‚ metabolism‚ and even improve mental faculties like memory and intelligence”. (Wikipedia) There are many risks associated
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Identification of the problem: The Human Genome Project ranks right up there at the top of the scale of scientific advances. The Human Genome Project is useful in many ways and also can be misused in many ways. The problems of Human Genome Project are - Very expensive research Ethical issues The end results of the possible cure might not available to everyone Not natural or safe Who will be allowed access to such abilities Wrong hands and wrong purposes Side affects Discussion: To research
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to gene therapy. Firstly‚ it is difficult to target specific cells. However‚ researchers are continually developing more efficient vectors such as virosomes. Secondly‚ gene therapy can cause dangerous immune responses‚ as seen in the case of Jesse Gelsinger. However‚ researchers have begun to use vectors that don’t cause an immune response; such as adeno associated viruses‚ virosomes and liposomes. Scientists have also harvested cells and performed gene therapy outside the body (ex vivo). This method
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respected Critically evaluate Hippocratic oath What are the major suggestions of Nuremberg Code? State the context of Nuremberg trials. Write a paragraph on major suggestions of Helsinki Declaration. What message does gene therapy trial on Jesse Gelsinger convey? The fate of some of the bubble-babies put the biomedical engineering world in a dilemma. Why? If you were the judge who had to take the final decision on Terri Schiavo case‚ what could be your pronouncement? Explain (with supported
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modify our hair/eye color. God could not have addressed genetic engineering specifically in the Bible thousands of years ago‚ because the prophets who wrote the Bible did not have that technology available at the time. In September of 1999‚ Jesse Gelsinger was treated at University of Pennsylvania for an inherited enzyme deficiency. She suffered an extreme immune reaction and died 4 days after the gene therapy treatment. After several days‚ the researchers still had no idea what went wrong. That
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The last five decades have seen significant development in medical and biomedical technology and applications. The increase in research and development in fields such as biomechanics‚ biomaterials‚ cloning‚ tissue engineering‚ and medicine have spawned a whole new branch of philosophy aptly named bioethics. Bioethics‚ the study of the ethical and moral implications of biological research and biomedical advances‚ emerged in the early 1970s as its own discipline. As medical technology is improved
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Who’s watching the Watchdog? Who’s watching the Watchdog? What ethical issue is at the heart of the article? The ethical issue at the heart of the article is the Common Rules. The Common Rules govern the ethical practice for researchers using participants. Sometimes the guidelines are unclear and not entirely effective in protecting patients in research studies. “Current trends in research and it’s regulation continue to erode the requirement
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The clash between the animal rights activists and researchers over the issue of‚ whether animals should be allowed to be studied in research labs‚ or not‚ is constantly debated. The heavily accepted plea of the animal rights activists to remove animals from testing is a completely preposterous goal‚ and when looked further in to‚ have extreme flaws and negative adverse effects on scientific progress and the world. Because of this‚ scientific research on animals should continue until other sustainable
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