STEVENS-JOHNSON SYNDROME: PATHOPHYSIOLOGY‚ ETIOLOGY‚ DIAGNOSIS AND MANAGEMENT. Roberto Carmona Florida International University Abstract: Steven Johnson Syndrome is an inmune disease charactherized by a detachment of the epidermis from dermis. It could be fatal and the pathophysilogy involves a complex hypersensitivity reaction with the participation of T lymphocytes that induce keratinocyte’s apoptosis. The syndrome can be cause by drigs‚ infections and malignancies. The diagnosis
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Abstract The article describes a technique for processing liquid radioactive waste water using membrane techniques to single out only radioactive waste components without affecting the salt ballast. This solution dramatically reduces the amount of radioactive concentrates to be long-term storage‚ and provides an opportunity to re-use treated water and chemicals. Keywords. Liquid radioactive waste‚ radioactive waste water purification‚ reverse osmosis‚ selective extraction of radionuclides. Introduction
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Muscle adaptations to the increase in energy demands at the start of exercise Introduction The transition from rest to exercise is associated with a huge upsurge in energy expenditure‚ due primarily to skeletal muscle contractions (Connett & Sahlin‚ 1996). Contractions require energy in the form of adenosine tri-phosphate (ATP). ATP stores in muscle are around 8mmol/l and are exhausted within 2s of exercise (Connett & Sahlin‚ 1996). To continue exercise and maintain ATP homeostasis‚ ATP
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A Seminar Report On “ORGANIC LIGHT EMITTING DIODE INDEX S.NO TOPIC PAGE NO 1) Introduction…………………………….……………….….………………6. 2) OLED vs LED……………………..…………………….……………..…..7 3) History………………………………………………….…………….……..8 4) Organic Light Emitting Diode……………………….……………….…….10 5) Structure of OLED………………….……………………..………………...11 6) OLED device operation and principle……........…………..………………...12 7) Working
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Abstract The scope of this paper focuses on Salbutamol as a drug and the mechanisms behind; 1) The drug function. 2) Development of drug resistance. 3) The clinical features of drug resistant individuals. 4) How to diagnose them. 5) Management of these patients. Salbutamol resistance Salbutamol is a beta 2 adrenergic receptor agonist that is short acting and used in the management of conditions that cause bronchospasms/bronchoconstriction. These conditions mainly include
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Session 28 Safety Pharmacology Studies for Human Pharmaceuticals This guidance was developed to help protect clinical trial participants and patients receiving marketed products from potential adverse effects of pharmaceuticals‚ while avoiding unnecessary use of animals and other resources. This guidance provides a definition‚ general principles‚ and recommendations for safety pharmacology studies. Pharmacology studies have been performed worldwide for many years as part of the nonclinical
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in our drinking water can have adverse effects on our body. You can measure the water hardness by EDTA titrations. EDTA is a disodium salt that stands for ethylenediaminetetraacetic acid and it is a chelating agent. Chelation is the process of a ligand forms a complex with a metal ion. Eriochrome Black T is an indicator you add to the water sample that will turn the water pink if metal ions exist. Through the process of titration‚ carefully adding EDTA to the water sample with the Eriochrome Black
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HCR240 Human Pathophysiology Lesson 1 Quiz This assignment is worth 40 points. Please make sure you have answered all questions prior to submitting. Once you click the submit button‚ you will not be able to return. Question 1 of 40 A 9-year-old patient is admitted to a pediatric unit with Duchenne muscular dystrophy. Which of the following traits was this condition inherited from? Sex-linked dominant Sex-influenced Sex-limited Sex-linked recessive Question 2 of 40 A 70-year-old
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noncompetitive inhibitor where the inhibitor binds to the opposite side of the active site‚ changing the shape of the enzyme‚ and stops it from being active. Cell signaling is also affected by the structure of the protein because in this activity‚ ligand binds specifically to receptor‚ causing it to catalyze reactions. If a gap junctions‚ for instance‚ is formed‚ then the shape of the junctions would allow for passages of regulatory ions or molecules‚ thus regulating the
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Liposomes Definition and background10 Liposomes were discovered in the early 1960’s and subsequently studied as cell membrane models. They have since gained recognition in the field of drug delivery. Liposomes are spherical vesicles which can be thought of as a hollow sphere they are composed of a bilayer membrane which entraps an aqueous core. The particle size of liposomes ranges from 20 nm to 10 μm in diameter. Liposomes vary in charge and in size depending on their manufacturing protocol
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