INTRODUCTION A major obstacle in the successful treatment of cancer is the development of resistance mechanisms to drug treatment. Various cellular changes that have been implicated in the development of drug resistance in cancer cells include: the increased expressions of P-glycoprotein (a multidrug transport protein) and multidrug resistance-associated protein (MRP-1); increased levels of the cellular detoxification protein‚ glutathione; and changes in the expression of apoptosis associated
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face-threatening act. We recall that a face-threatening act is a message that can seem to challenge the image we want to project. Defensiveness is then the process of protecting our presenting self‚ our face. There are a few different defense mechanisms that people use. Rationalizations are logical but untrue explanations of behavior that is unacceptable to the self. An example of this is with my boyfriend‚ Spencer. Spencer asks me to help him with his laundry a lot since he never has time
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Mobile Care System With Alert Mechanism Ren-Guey Lee‚ Member‚ IEEE‚ Kuei-Chien Chen‚ Chun-Chieh Hsiao‚ and Chwan-Lu Tseng Abstract—Hypertension and arrhythmia are chronic diseases‚ which can be effectively prevented and controlled only if the physiological parameters of the patient are constantly monitored‚ along with the full support of the health education and professional medical care. In this paper‚ a role-based intelligent mobile care system with alert mechanism in chronic care environment is
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The introduction to the "theory of descriptions" was written by Bertrand Russell in an article titled "On Denoting" in 1905 and is one of the most studied chapters in analytic philosophy. It is said‚ "...the choice of whether to accept or reject Russell ’s theory has had profound consequences for our philosophy of language‚ epistemology‚ and metaphysics." One of Russell ’s motivations for developing the "theory of descriptions" was his abandonment of his "theory of denoting concepts‚" which is
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STRESS COPING MECHANISMS AMONG YOUTH (PGDM STUDENTS) 1. INTRODUCTION A word which we consistently heard and feared from the day we thought of doing management studies is “STRESS”. Management studies have been perceived as a hectic and stressful course from the inception of the same. Every individual has his own methods for coping up with the stress; like playing games‚ working out in gym‚ listening to music‚ doing yoga‚ chatting with friends etc.
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Santhosh Varadarajan Mekanism: Engineering Viral Marketing June 30th‚ 2014 In early 2011‚ Jason Harris‚ Mekanism’s president‚ and Pete Caban‚ CEO were considering converting Mekanism from a specialized‚ niche production company‚ to a full-service ad agency. At the time‚ Mekanism was a digital social media production company that developed viral marketing campaigns for various firms. They had great success seeing 68% annual growth in billings which was fasted than they had predicted. In 2010
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The five accounting cycles in an organization are: The revenue cycle‚ expenditure cycle‚ financing cycle‚ fixed assets cycle‚ and the conversion cycle. The revenue cycle is the set of activities in a business bringing about the exchange of goods or services with customers or consumers for cash‚ such as sales orders‚ accounts receivables‚ cash receipts (Hall‚ 2004)‚ and cost of goods sold. The expenditure cycle is an external exchange of information between vendors and the company. The expenditure
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Vitamin D HW205 Kaplan University Vitamin D is actually not classified as a vitamin. It is considered a prohormone and its active form functions as a hormone. In the earlier years Vitamin D was always associated directly with milk. As the progression of research has shown‚ Vitamin D is prominent in many foods. The most vitamin D rich foods are milk‚ margarine‚ fortified cereals‚ fortified orange juice‚ canned tuna and other fish such as mackerel and salmon‚ and some whole
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Pamela Reed House 2/24/11 Marketing Plan Special Topics 492 The BMW Company (2010 6 Series 650i Convertible) BMW has come a long reached many milestones since its introduction into the German market through much anticipation and a well thought out plans towards becoming the one of the most popular family of luxurious cars globally. Rapp-Motorenwerke was a firm that first invented aircraft engines and motorcycle engines in 1913 before the firm invented Austin Stevens’s cars. By merging with
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Heather Comp. 1 Steve McCurry Assignment Photo 1. An elderly man stares at you with a typical expression of one of the artists subjects‚ seeming to have no understanding of what would make them an interesting photograph. The main focus is placed on his aged face; his brown skin has an appearance of leather‚ with wrinkles so deep he almost looks to be made of something other than flesh. A neutral expression seems to convey he is neither joyed nor displeased with the position he has been handed
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